Method for determining the functional residual capacity of lungs and a ventilator for practicing said method

• US 5,540,233 A
• Filed: 10/24/1994
• Issued: 07/30/1996
• Est. Priority Date: 10/22/1993
• Status: Expired due to Term

• Current Assignee: Maquet Critical Care AB (Getinge AB)
• Original Assignee: Siemens-Elema AB (Siemens AG)
• Inventors: Castor, Rolf, Brauer, Stefan, Larsson, Anders, Olsson, Sven G.
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US08/327,990
• Time in Patent Office: 645 Days
• Field of Search: 128/716, 128/719, 128/725
• US Class Current: 600/538
• CPC Class Codes: A61B 5/0813 Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
• CPC Class Codes: A61B 5/091 Measuring volume of inspired or expired gases, e.g. to determine lung capacity

Abstract

In a method and a ventilator device for measuring the functional residual capacity, FRC, of lungs, a trace gas is mixed with a breathing gas in a gas mixer and the mixture os fed into the lungs via an inspiratory tube. When a predetermined concentration of trace gas is achieved in the lungs, the supply of trace gas is stopped, and a washout phase starts. During the washout phase, the concentration of trace gas in expired gas and the flow of expired gas are measured. The measurement values are sent to an analyzer which calculates the volume of trace gas in the lungs. Functional residual capacity can then be determined from the calculated volume of trace gas. The trace gas is preferably SF₆.

Claims

1. A method for determining the functional residual capacity of lungs, comprising the steps of:

supplying a predetermined concentration of a trace gas to a breathing gas and feeding said breathing gas with said predetermined concentration of said trace gas into the lungs through a gas meter during a wash-in phase;

measuring the concentration of said trace gas in gas inspired by and expired from the lungs with said gas meter;

stopping the supply of said trace gas when the concentration of said trace gas measured in the expired gas becomes identical to the concentration measured in the inspired gas;

starting a washout phase;

measuring the concentration of said trace gas in the expired gas in said washout phase with said gas meter until the measured concentration falls below a predetermined threshold value;

measuring the flow of expired gas for every respiratory cycle in said washout phase; and

at an end of said washout phase, calculating the volume of said trace gas expired during the washout phase from the measured concentration of said trace gas in the expired gas and the measured flow of expired gas, and calculating the functional residual capacity of the lungs by dividing said volume, of said trace gas by said concentration of said trace gas.

2. A method as claimed in claim 1, comprising the additional step of setting said gas meter to a null level for the concentration of said trace gas at said predetermined concentration.

3. A method as claimed in claim 1, comprising the additional steps of:

storing measurement values obtained during the washout phase in a memory;

measuring a signal drift of said gas meter; and

correcting the stored measurement values for the measured signal drift before calculating said volume.

4. A method as claimed in claim 1 wherein the step of measuring the concentration of said trace gas in the inspired gas comprises measuring the concentration of said trace gas in the inspired gas during said washout phase followed by measuring a volume of residual trace gas and thereby identifying a re-breathed volume of trace gas, and correcting the calculated volume of trace gas by compensating for said re-breathed volume of trace gas.

5. A method for determining the functional residual capacity of lungs, comprising the steps of:

feeding a breathing gas comprising a predetermined concentration of a trace gas into the lungs through a gas meter during a wash-in phase;

measuring an inspired concentration of said trace gas in gas inspired by the lungs and an expired concentration of said trace gas expired from the lungs with said gas meter during said wash-in phase until the concentration of said trace gas in the inspired gas is the same as the concentration of said trace gas in the expired gas;

measuring an inspired flow of gas for each respiratory cycle in the wash-in phase;

measuring an expired flow of gas for each respiratory cycle in said wash-in phase;

calculating a volume of inspired trace gas in said wash-in phase from the measured inspired concentration of said trace gas and the measured inspired flow of gas and calculating a volume of expired trace gas from the measured expired concentration of said trace gas and the measured expired flow of gas; and

calculating a volume of said trace gas in the lungs by subtracting the volume of expired trace gas from the volume of inspired trace gas, and calculating the functional residual capacity of the lungs by dividing said volume of trace gas in the lungs by said expired concentration of said trace gas.

6. An apparatus for ventilating a patient comprising:

ventilator means for supplying breathing gas to and carrying expired gas away from the lungs of said patient;

a gas source, connected to said ventilator means, for supplying a trace gas mixed with said breathing gas to the lungs of said patient during a wash-in phase during the inspiratory phase of a plurality of respiratory cycles until the lungs contain a predetermined concentration of the trace gas;

gas meter means, through which the mixture of said breathing gas and said trace gas passes, for measuring the concentration of said trace gas during the wash-in phase and during a subsequent washout phase in the expiratory phase of said plurality of respiratory cycles until the concentration of said trace gas measured during the washout phase falls below a predetermined threshold value;

flow meter means for measuring expiratory flow during said washout phase; and

analyzer means supplied with said measured values for the trace gas concentration and expiratory flow during said washout phase, for determining the volume of trace gas leaving the lungs and, from said volume of trace gas leaving the lungs, determining the functional residual capacity of the lungs.

7. An apparatus as claimed in claim 6 wherein said analyzer means comprises a memory in which measurement values for the concentration of said trace gas and the flow of expired gas are stored during said washout phase.