Device and method for heating tissue in a patient's body

• US 5,540,679 A
• Filed: 07/01/1994
• Issued: 07/30/1996
• Est. Priority Date: 10/05/1992
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Corporation
• Inventors: Fram, Daniel B., Rowe, Donald S., Berns, Ellison, Ropiak, Susan M.
• Primary Examiner(s): Thaler, Michael H.
• Assistant Examiner(s): PEFFLEY, MICHAEL F
• Application Number:
  US08/270,060
• Time in Patent Office: 760 Days
• Field of Search: 607/100-105, 607/115, 607/116, 607/122, 606/27-33, 606/41, 606/42, 606/191-194
• US Class Current: 606/27
• CPC Class Codes: A61B 18/082 Probes or electrodes therefor
• CPC Class Codes: A61B 2017/00039 Electric or electromagnetic phenomena other than conductivity, e.g. capacity, inductivity, Hall effect
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00973 pedal-operated
• CPC Class Codes: A61B 2017/22062 to be filled with liquid
• CPC Class Codes: A61B 2018/046 in liquid form
• CPC Class Codes: A61B 2090/3933 Liquid markers
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

A balloon catheter is provided that includes a catheter shaft constructed for insertion into a blood vessel, a balloon mounted on the catheter shaft, and a heating device located within the balloon and arranged for heating fluid inside the balloon to permit heating of tissue by thermal conduction from the fluid to the tissue through a wall of the balloon. The balloon catheter is inserted into a blood vessel and the balloon is passed through the right atrium of the heart and into the coronary sinus of the heart. The balloon is inflated with the fluid, and the fluid is heated inside the balloon through use of the heating device, to cause heat to pass from the fluid to surrounding tissue by thermal conduction through the wall of the balloon.

Claims

1. A method of ablating electrically conductive pathways of a heart, comprising the steps of:

providing a balloon catheter comprising a catheter shaft constructed for insertion into a blood vessel, a balloon mounted on said catheter shaft, and a heating device located within said balloon for heating fluid inside said balloon to permit controlled heating of tissue by thermal conduction from said fluid to said tissue through a wall of said balloon,

said balloon having a compliance such that said balloon, when placed within the coronary sinus of said heart and inflated, is conformable to the wall of said coronary sinus over the entire wall-facing circumference of said balloon at each point along the length of said balloon without substantially dilating any portion of said coronary sinus contacted by said balloon, even when said balloon, inflated within said coronary sinus, has a diameter ratio over the length of said balloon exceeding 1.5 to 1,

inserting said balloon catheter into a blood vessel and causing said balloon to pass through the right atrium of said heart and into the coronary sinus of said heart,

selecting an inflated length of said balloon so as to enable said balloon to create a lesion having a size suitable for ablation of said electrically conductive pathways, and selecting an inflation pressure that will cause said balloon, when inflated with said fluid to said inflation pressure, to have said inflated length,

inflating said balloon with said fluid to said inflation pressure, said balloon conforming to the wall of said coronary sinus over the entire wall-facing circumference of said balloon at each point along the length of said balloon without substantially dilating any portion of said coronary sinus contacted by said balloon, said balloon, when inflated within said coronary sinus, having a diameter ratio over the length of said balloon exceeding 1.5 to 1, and

causing tissue necrosis while controlling the extent thereof, by heating said fluid inside said balloon through use of said heating device, to cause heat to pass from said fluid to surrounding tissue by thermal conduction through said wall of said balloon, said thermal conduction through said wall of said balloon resulting in said tissue necrosis.

2. A method in accordance with claim 1, wherein said fluid is heated with an intensity and duration sufficient to cause ablation of anomalous electrical fibers in said heart.

3. A method in accordance with claim 1, further comprising the step of:

performing electrophysiologic mapping by means of a plurality of electrophysiologic mapping electrodes mounted on said catheter shaft,

whereby electrophysiologic mapping and heating treatment are performed without exchange of catheter devices.

4. A method in accordance with claim 1, further comprising the step of providing feedback information to assist in control of said heating of tissue.

5. A method of ablating electrically conductive pathways of a heart, comprising the steps of:

providing a balloon catheter comprising a catheter shaft constructed for insertion into a blood vessel, a balloon mounted on said catheter shaft, and a heating device located within said balloon for heating fluid inside said balloon to permit controlled heating of tissue by thermal conduction from said fluid to said tissue through a wall of said balloon,

said balloon comprising a membrane of silicone rubber to ensure that said balloon is highly deformable under stress, said balloon having a compliance such that said balloon, when placed within the coronary sinus of said heart and inflated, is conformable to the wall of said coronary sinus without substantially dilating said coronary sinus,

inserting said balloon catheter into a blood vessel and causing said balloon to pass through the right atrium of said heart and into the coronary sinus of said heart,

selecting an inflated length of said balloon so as to enable said balloon to create a lesion having a size suitable for ablation of said electrically conductive pathways, and selecting an inflation pressure that will cause said balloon, when inflated with said fluid to said inflation pressure, to have said inflated length,

inflating said balloon with said fluid to said inflation pressure, said balloon conforming to the wall of said coronary sinus without substantially dilating said coronary sinus, and

causing tissue necrosis while controlling the extent thereof, by heating said fluid inside said balloon through use of said heating device, to cause heat to pass from said fluid to surrounding tissue by thermal conduction through said wall of said balloon, said thermal conduction through said wall of said balloon resulting in said tissue necrosis.

6. A method of ablating electrically conductive pathways of a heart, comprising the steps of:

providing a balloon catheter comprising a catheter shaft constructed for insertion into a blood vessel, a balloon mounted on said catheter shaft, and a heating device located within said balloon for heating fluid inside said balloon to permit controlled heating of tissue by thermal conduction from said fluid to said tissue through a wall of said balloon,

said balloon having a compliance such that the volume of said balloon exhibits at least a one-fold increase when the pressure within said balloon is increased by one-fold starting at a gauge pressure of one-half atmosphere, said compliance being such that said balloon, when placed within the coronary sinus of said heart and inflated, is conformable to the wall of said coronary sinus without substantially dilating said coronary sinus,

inserting said balloon catheter into a blood vessel and causing said balloon to pass through the right atrium of said heart and into the coronary sinus of said heart,

selecting an inflated length of said balloon so as to enable said balloon to create a lesion having a size suitable for ablation of said electrically conductive pathways, and selecting an inflation pressure that will cause said balloon, when inflated with said fluid to said inflation pressure, to have said inflated length,

inflating said balloon with said fluid to said inflation pressure, said balloon conforming to the wall of said coronary sinus without substantially dilating said coronary sinus, and

causing tissue necrosis while controlling the extent thereof, by heating said fluid inside said balloon through use of said heating device, to cause heat to pass from said fluid to surrounding tissue by thermal conduction through said wall of said balloon, said thermal conduction through said wall of said balloon resulting in said tissue necrosis.