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Three-dimensional bone marrow cell and tissue culture system

  • US 5,541,107 A
  • Filed: 04/06/1995
  • Issued: 07/30/1996
  • Est. Priority Date: 04/18/1986
  • Status: Expired due to Term
First Claim
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1. A three-dimensional bone marrow cell culture comprising hematopoietic cells cultured on a living stromal tissue prepared in vitro, said living stromal tissue comprising stromal cells and connective tissue proteins naturally secreted by the stromal cells attached to and substantially enveloping a framework composed of a biocompatible, non-living material formed into a three-dimensional structure having interstitial spaces bridged by the stromal cells.

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