Method and apparatus for cardiovascular diagnosis

• US 5,542,421 A
• Filed: 08/30/1994
• Issued: 08/06/1996
• Est. Priority Date: 07/31/1992
• Status: Expired due to Term

• Current Assignee: Frederick Erdman Association
• Original Assignee: Frederick Erdman Association
• Inventors: Erdman, Frank H.
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): NASSER, ROBERT L
• Application Number:
  US08/297,899
• Time in Patent Office: 707 Days
• Field of Search: 128/633, 128/664-6, 128/736, 128/748, 128/690, 128/691, 128/687, 128/632, 128/774
• US Class Current: 600/477
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02422 within occluders
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/441 Skin evaluation, e.g. for skin disorder diagnosis
• CPC Class Codes: A61B 5/4884 inducing physiological or psychological stress, e.g. applications for stress testing
• CPC Class Codes: A61B 5/6825 Hand
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure

Abstract

A non-invasive method and apparatus for sensing relative blood conditions in extremities, such as using photoelectric dermachromography to measure differential blood flow and/or pooling between extremities, for the purpose of diagnosing cardiovascular conditions. Reflective colorimeters are employed for performing comparative light reflection rheology (LRR). The resting, steady-state LRR for both the left and right palms are simultaneously measured when both arms are in a raised, steady-state condition, and again when both arms are in a lowered, steady-state condition, thereby providing a repeatable measurement of overall vasomotor tone, the tone of the smooth muscles of the arterial walls. Two portable light gauges are used, each including a plurality of light sources such as light-emitting diodes (LEDs) arranged around at least one light detector. Each gauge is removably attachable to the palms of the hands of the patient whose vasomotor tone is to be determined. The gauges are removably attached to the palms so that the hands are movable, and measurements are taken of both hands in a raised, substantially steady-state UP condition, and then again while both hands are in a lowered, substantially steady-state DOWN condition. After a series of these UP and DOWN measurements are taken, the gauges are switched and another series of UP and DOWN measurements with the gauges reversed are taken. Each gauge is independently calibrated by using standardized reference scales.

Claims

1. A method of determining cardiovascular conditions comprising the steps of:

removably attaching a sensor to a surface of each of a pair of extremities of a patient for measuring a physical parameter indicative of cardiovascular conditions;

measuring said parameter substantially simultaneously on both extremities while both extremities are in a raised, steady-state condition;

measuring said parameter substantially simultaneously on both extremities while both extremities are in a lowered, steady-state condition;

comparing the measurements obtained in the raised, steady-state condition with the measurements obtained in the lowered, steady-state condition to determine cardiovascular conditions; and

recording the result of said comparing step.

2. A method in accordance with claim 1, wherein said surface of each of a pair of extremities is the palm of each hand of a patient.

3. A method in accordance with claim 2, wherein each sensor exerts a substantially equal force on each palm.

4. A method in accordance with claim 1, further including performing said steps of attaching said sensors, measuring said parameter while extremities are in said raised condition, measuring said parameter while extremities are in said lowered condition, and comparing said measurements with said sensors in a first orientation relative to respective extremities, said method further comprising repeating said steps of attaching said sensor unit, measuring said parameter while extremities are in said raised condition, measuring said parameter while extremities are in said lowered condition, and comparing said measurements with said sensors in a second configuration which is the reverse of said first configuration, prior to said recording step.

5. A method according to claim 1, further comprising the step of:

calibrating the sensor for measuring the parameter.

6. A method according to claim 5, wherein said step of calibrating the sensor includes removably attaching said sensor to an inanimate object having a known physical parameter.

7. A method according to claim 6, wherein said step of calibrating the sensor further includes maintaining a temperature of said inanimate object at a temperature approximate to that of said patient.

8. A non-invasive method for determining vasomotor tone comprising the steps of:

removably attaching a light sensor unit to a surface of each of a pair of extremities of a patient for measuring a light reflection parameter of each of the extremities;

measuring the light reflection parameter of the surfaces of the extremities substantially simultaneously on both extremities while both extremities are in a raised, steady-state condition;

measuring the light reflection parameter of the surfaces of the extremities substantially simultaneously on both extremities while both extremities are in a lowered, steady-state condition;

comparing the light reflection parameter measurements obtained in the raised, steady-state condition with the light reflection parameter measurements obtained in the lowered, steady-state condition to determine vasomotor tone; and

recording the determined vasomotor tone.

9. A method in accordance with claim 8, wherein said surface of each of said pair of extremities is the palm of each hand of a patient.

10. A method in accordance with claim 9, wherein each sensor unit exerts a substantially equal force on each palm.

11. A method in accordance with claim 8, further including performing said steps of attaching said light sensor unit, measuring said parameter while extremities are in a raised condition, measuring said parameter while extremities are in a lowered condition, and comparing said measurements with said light sensor unit in a first configuration,

said method further comprising repeating said steps of attaching said light sensor unit, measuring said parameter while extremities are in a raised condition, measuring said parameter while extremities are in a lowered condition, and comparing said measurements with said light sensor unit in a second configuration which is the reverse of said first configuration, prior to said recording step.

12. A method according to claim 8, further comprising the step of:

calibrating the sensor unit for measuring the parameter.

13. A method according to claim 12, wherein said step of calibrating the sensor unit includes removably attaching said sensor unit to an inanimate object having a known physical parameter.

14. A method according to claim 13, wherein said step of calibrating the sensor unit further includes maintaining a temperature of said inanimate object at a temperature approximate to that of said patient.

15. A non-invasive method of determining cardiovascular conditions comprising the steps of:

sensing, at a surface of each of a pair of extremities of a patient, a physical parameter indicative of cardiovascular conditions;

sensing said parameter substantially simultaneously on both extremities while both extremities are in a raised, steady-state condition;

sensing said parameter substantially simultaneously on both extremities while both extremities are in a lowered, steady-state condition;

comparing the sensed parameter obtained in the raised, steady-state condition with the sensed parameter obtained in the lowered, steady-state condition to determine cardiovascular conditions; and

recording results of said comparing step.

16. A method according to claim 15, wherein said sensing step is performed by a sensor unit which includes a light gauge and said physical parameter is a light reflection parameter.

17. A method according to claim 16, wherein each sensor unit exerts a substantially equal force on each extremity.

18. A method according to claim 16, further comprising the step of reversing an orientation of the sensor units relative to respective extremities and repeating said steps of attaching said sensor units, measuring said parameter while both extremities are in said raised condition, measuring said parameter while both extremities are in said lowered condition, comparing the measurements obtained in the raised condition with the measurements obtained in the lowered condition with said sensor units in said reversed orientation prior to recording the results of said comparing step.

19. A method according to claim 16, further comprising the step of:

calibrating the sensor unit for measuring the parameter.

20. A method according to claim 19, wherein said step of calibrating the sensor unit includes removably attaching said sensor unit to an inanimate object having a known physical parameter.

21. A method according to claim 20, wherein said step of calibrating the sensor unit further includes maintaining a temperature of said inanimate object at a temperature approximate to that of said patient.

22. In an Erdman Therapy method to improve blood flow rates for patients with high vasomotor tone through application of heat, massage, or ultrasound therapies, and to improve blood flow rates for patients with low vasomotor tone through cold applications on spinal muscles or on portions of spinal muscles, the improvement comprising the steps of:

removably attaching a sensor unit to a surface of each of a pair of extremities of a patient for measuring a physical parameter indicative of cardiovascular conditions;

measuring said parameter substantially simultaneously on both extremities while both extremities are in a raised, steady-state condition;

measuring said parameter substantially simultaneously on both extremities while both extremities are in a lowered, steady-state condition;

comparing the measurements obtained in the raised, steady-state condition with the measurements obtained in the lowered, steady-state condition; and

implementing a therapy based on the results of said comparing step.

23. A method according to claim 22, wherein said sensor unit includes a light gauge and said physical parameter is a light reflection parameter.

24. A method according to claim 22, further comprising the step of recording said result of said comparing step.

25. A method according to claim 22, wherein each sensor unit exerts a substantially equal force on each extremity.

26. A method according to claim 22, further comprising the step of reversing an orientation of the sensor units relative to respective extremities and repeating said steps of attaching said sensor units, measuring said parameter while both extremities are in said raised condition, measuring said parameter while both extremities are in said lowered condition, comparing the measurements obtained in the raised condition with the measurements obtained in the lowered condition with said sensor units in said reversed orientation prior to implementing the therapy based on the results of said comparing step.

27. A method according to claim 22, further comprising the step of:

calibrating the sensor unit for measuring the parameter.

28. A method according to claim 27, wherein said step of calibrating the sensor unit includes removably attaching said sensor unit to an inanimate object having a known physical parameter.

29. A method according to claim 28, wherein said step of calibrating the sensor unit further includes maintaining a temperature of said inanimate object at a temperature approximate to that of said patient.

30. In an Erdman Therapy method to improve blood flow rates for patients with high vasomotor tone through application of heat, massage, or ultrasound therapies, and to improve blood flow rates for patients with low vasomotor tone through cold applications on spinal muscles or on portions of spinal muscles, the improvement comprising the steps of:

sensing, at a surface of each of a pair of extremities of a patient, a physical parameter indicative of cardiovascular condition;

sensing said parameter substantially simultaneously on both extremities while both extremities are in a raised, steady-state condition;

sensing said parameter substantially simultaneously on both extremities while both extremities are in a lowered, steady-state condition;

comparing the sensed parameter obtained in the raised, steady-state condition with the sensed parameter obtained in the lowered, steady-state condition; and

implementing a therapy based on results of said comparing step.

31. A device comprising:

at least two light sensor units removably attachable to extremities of a patient for measuring a light reflection parameter;

controller means for controlling said light sensor units during the performance of light reflection parameter measurements;

comparing means for comparing a light reflection parameter measurement made substantially simultaneously on two extremities of a patient while both extremities of a patient are in a raised, steady-state condition with a light reflection parameter measurement made substantially simultaneously on both extremities of a patient while both extremities of a patient are in a lowered, steady-state condition; and

indicating means for indicating a result of said comparing step.

32. A device according to claim 31, wherein each of said at least two light sensor units includes a light emitter means for emitting light and a light detector means for receiving light.

33. A device according to claim 32, wherein said light emitter means includes a plurality of light emitting diodes.

34. A device according to claim 32, wherein said light emitter means includes an light supplying optical fiber operatively connected to a light emitter located remote to said at least two light sensor units.

35. A device according to claim 32, wherein said light detector means includes an optical fiber operatively connected to receive said light reflection parameter and transmit said light reflection parameter to a light detector located remote to said at least two light sensor units.

36. A device according to claim 31, wherein said comparing means includes a graphic display of said light reflection parameter measurement made substantially simultaneously on two extremities of a patient while both extremities of a patient are in said raised, steady-state condition with a light reflection parameter measurement made substantially simultaneously on both extremities of a patient while both extremities of said patient are in said lowered, steady-state condition, and wherein said indicating means includes a scale adjacent to said graph display.

37. A device according to claim 31, wherein said comparing means includes means for subtracting said light reflection parameter measurement made substantially simultaneously on two extremities of a patient while both extremities of a patient are in a raised, steady-state condition from a light reflection parameter measurement made substantially simultaneously on both extremities of a patient while both extremities of a patient are in a lowered, steady-state condition, and wherein said indicating means includes a display of results of said subtraction.

38. A device in accordance with claim 31, further comprising:

calibrating means for calibrating the light sensor units for measuring the light reflection parameter.

39. A device according to claim 38, wherein said calibration means includes inanimate objects having known light reflection parameter.

40. A device according to claim 39, wherein said calibration means further includes means for maintaining said inanimate objects at a predetermined temperature approximate to a temperature of said patient.