Low profile perfusion catheter

• US 5,542,926 A
• Filed: 03/08/1994
• Issued: 08/06/1996
• Est. Priority Date: 06/30/1993
• Status: Expired due to Term

• Current Assignee: CardioVascular Dynamics, Inc. (Radiance Medical Systems, Inc.)
• Original Assignee: CardioVascular Dynamics, Inc. (Radiance Medical Systems, Inc.)
• Inventors: Crocker, Michael
• Primary Examiner(s): McDermott, Corrine M.
• Assistant Examiner(s): GRING, NOELLE K
• Application Number:
  US08/208,617
• Time in Patent Office: 882 Days
• Field of Search: 604/95, 604/96, 604/97, 604/98, 604/99, 604/100, 604/101, 604/102, 604/103, 606/194
• US Class Current: 604/102.02
• CPC Class Codes: A61M 2025/1063 having only one lumen used for guide wire and inflation, e.g. to minimise the diameter
• CPC Class Codes: A61M 2025/1075 having a balloon composed of several layers, e.g. by coating or embedding
• CPC Class Codes: A61M 2025/1097 with perfusion means for enabling blood circulation only while the balloon is in an inflated state, e.g. temporary by-pass within balloon
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

Disclosed is a Low Profile Perfusion Catheter, for use in coronary angioplasty applications. Preferably, the catheter is provided with an inflatable dilatation balloon, and a perfusion lumen extending therethrough. The diameter of the perfusion lumen is enlargable from a first, reduced diameter to a second, enlarged diameter. In one embodiment, an axially movable tubular support is movable within the lumen from a proximal, insertion position to a distal perfusion position. In another embodiment, the support is radially expandable. In a further embodiment, a porus drug delivery balloon is provided.

Claims

1. A catheter comprising:

an elongate, flexible tubular body;

a drug permeable delivery balloon on the tubular body in fluid communication with a first inflation lumen extending through the tubular body, said delivery balloon enlargeable from a first reduced outer diameter to a second, enlarged outer diameter;

a perfusion conduit extending through said delivery balloon, at least a portion of said perfusion conduit expandable from a first reduced diameter to a second enlarged diameter;

at least one influent port proximal to said balloon, said influent port extending through the wall of the tubular body and communicating with said perfusion conduit;

at least one effluent port distal to said balloon, said effluent port extending through the wall of the tubular body and communicating with said perfusion conduit; and

a support located within said perfusion conduit for reversibly maintaining the perfusion conduit in the second, enlarged diameter;

wherein said support is axially movable from a first, proximal position to a second, distal position, thereby expanding the perfusion conduit from the first, reduced diameter to the second, enlarged diameter.

2. A catheter as in claim 1, wherein said delivery balloon comprises a plurality of perforations for expressing said drug.

3. A catheter as in claim 2, wherein said perforations are between about 100μ

and about 300μ

in diameter.

4. A catheter as in claim 1, further comprising an inflation balloon in fluid communication with a second inflation lumen disposed within said delivery balloon.

5. A catheter as in claim 4, wherein said inflation balloon is secured to said delivery balloon so that deflation of said inflation balloon causes a reduction in diameter of said delivery balloon.

6. A catheter as in claim 5, further comprising a proximal seal between said inflation balloon and said delivery balloon, and a distal seal between said inflation balloon and said delivery balloon.

7. A catheter as in claim 1, further comprising an elongate flexible push wire extending through and axially movably disposed within said tubular body, for manipulating said support.

8. A catheter comprising:

an elongate, flexible tubular body;

an inflatable dilatation balloon on the tubular body in fluid communication with a first inflation lumen;

a drug delivery balloon on the tubular body in fluid communication with a second delivery lumen, said delivery balloon disposed about the dilatation balloon;

a perfusion conduit extending through said delivery balloon, at least a portion of said perfusion conduit expandable from a first reduced diameter to a second enlarged diameter;

at least one influent port proximal to said dilatation balloon, said influent port extending through the wall of the tubular body and communicating with said perfusion conduit;

at least one effluent port distal to said dilatation balloon, said effluent port extending through the wall of the tubular body and communicating with said perfusion conduit; and

a support located within said perfusion conduit for selectively maintaining the perfusion conduit in the second, enlarged diameter;

wherein said support is axially movable from a first, proximal position to a second, distal position, thereby expanding the perfusion conduit from the first, reduced diameter to the second, enlarged diameter.

9. A catheter comprising:

an elongate, flexible tubular body having an inflation lumen extending axially therethrough;

an inflatable balloon on the tubular body in fluid communication with the inflation lumen, said balloon enlargeable from a first reduced outer diameter to a second, enlarged outer diameter;

a perfusion conduit extending through said balloon, at least a portion of said perfusion conduit expandable from a first reduced diameter to a second enlarged diameter;

at least one influent port proximal to said balloon, said influent port extending through the wall of the tubular body and communicating with said perfusion conduit;

at least one effluent port distal to said balloon, said effluent port extending through the wall of the tubular body and communicating with said perfusion conduit; and

a support located within the catheter for selectively maintaining the perfusion conduit in the second, enlarged diameter;

wherein said support is axially movable from a first, proximal position to a second, distal position, thereby expanding the perfusion conduit from the first, reduced diameter to the second, enlarged diameter.