Artificial kidney

• US 5,545,131 A
• Filed: 11/30/1994
• Issued: 08/13/1996
• Est. Priority Date: 04/28/1994
• Status: Expired due to Fees

• Current Assignee: RenalTech International LLC
• Original Assignee: White Eagle International Technologies, LP
• Inventors: Davankov, Vadim A.
• Primary Examiner(s): CLARKE, ROBERT A
• Application Number:
  US08/346,871
• Time in Patent Office: 622 Days
• Field of Search: 604/4, 604/6, 604/29, 210/646-648
• US Class Current: 604/5.04
• CPC Class Codes: A61M 1/3679 by absorption A61M1/3675 takes precedence

Abstract

An artificial kidney system comprises an artificial kidney forming container having an inlet blood port connectable with a patient'"'"'s artery and an outlet blood port connectable with a patient'"'"'s vein so that blood from the patient'"'"'s artery can flow through the inlet port into the container, then through an inner space of the container and then through the outlet blood port into the patient'"'"'s vein, the inner space of the container being filled with an adsorbent for removing harmful and toxic compounds from a stream of blood flowing in the inner space from the inlet blood port to the outlet blood port, the container being provided with a separate chamber formed inside the inner space and limited by a semi-permeable polymeric ultrafiltration-type membrane which allows water and dissolved small molecules to be transported from blood into the chamber, and suction element connectable with the separate chamber so that the water and the dissolved small molecules are transported from blood into the separate chamber and further outside of the container under the action of suction of the suction element.

Claims

1. An artificial kidney system, comprising an artificial kidney forming container having an inlet blood port connectable with a patient'"'"'s artery and an outlet blood port connectable with a patient'"'"'s vein so that blood from the patient'"'"'s artery can flow through said inlet port into said container, then through an inner space of said container and then through said outlet blood port into the patient'"'"'s vein, said inner space of said container being filled with an adsorbent for removing harmful and toxic compounds from a stream of blood flowing in said inner space from said inlet blood port to said outlet blood port, said container being provided with a separate chamber formed inside said inner space and limited by a semi-permeable polymeric ultrafiltration-type membrane which allows water and dissolved small molecules to be transported from blood into said chamber;

suction means connected with said separate chamber so that the water and the dissolved small molecules are transported from blood into said separate chamber and further outside of said container under the action of suction of said suction means, said container having a urine outlet communicated with said separate chamber; and

artificial ureter forming tube means connecting said urine outlet of said container with said suction means so that urine with the water and dissolved small molecules is withdrawn from said separate chamber through said artificial ureter forming tube means, said suction means including a vacuum providing vessel, said artificial ureter tube means having one end connected with said urine outlet port and another end introduced into an interior of said vacuum vessel, said vacuum vessel being formed as an elastic vessel which is squeezable by a patient and restorable under elastic action of said vessel so as to form vacuum in its interior.

2. An artificial kidney as defined in claim 1, wherein said suction means include a vacuum providing vessel, said artificial ureter tube means having one end connected with said urine outlet port and another end introduced into an interior of said vacuum vessel.

3. An artificial kidney as defined in claim 2, wherein said separate chamber has a permeable wall, said semi-permeable polymeric ultrafiltration-type membrane being arranged on said permeable wall.

4. An artificial kidney as defined in claim 3, wherein said permeable wall of said separate chamber is composed of porous material.

5. An artificial kidney as defined in claim 1;

and further comprising two porous filter elements, one of said filter elements being located between said inlet port and said inner space of said container and the other of said filter elements being located between said outlet port and said inner space of said container.

6. An artificial kidney as defined in claim 1;

and further comprising an arterial cannula implantable in an artery of a patient and a venous cannula implantable in a vein of a patient, said arterial cannula being connectable with said blood inlet port while said venous cannula is connectable with said blood outlet port of said container, said cannulae being also connectable with one another in an inoperative position of the artificial kidney system.

7. An artificial kidney as defined in claim 1, wherein said vacuum vessel has an opening provided with a seal;

and further comprising a hollow needle connectable with said another end of said artificial ureter forming tube means and piercing said seal so as to communicate said artificial ureter tube means with the interior of said vacuum vessel.

8. An artificial kidney system, comprising an artificial kidney forming container having an inlet blood port connectable with a patient'"'"'s artery and an outlet blood port connectable with a patient'"'"'s vein so that blood from the patient'"'"'s artery can flow through said inlet port into said container, then through an inner space of said container and then through said outlet blood port into the patient'"'"'s vein, said inner space of said container being filled with an adsorbent for removing harmful and toxic compounds from a stream of blood flowing in said inner space from said inlet blood port to said outlet blood port, said container being provided with a separate chamber formed inside said inner space and limited by a semi-permeable polymeric ultrafiltration-type membrane which allows water and dissolved small molecules to be transported from blood into said chamber;

suction means connected with said separate chamber so that the water and the dissolved small molecules are transported from blood into said separate chamber and further outside of said container under the action of suction of said suction means, said container having a urine outlet communicated with said separate chamber;

artificial ureter forming tube means connecting said urine outlet of said container with said suction means so that urine with the water and dissolved small molecules is withdrawn from said separate chamber through said artificial ureter forming tube means, said vacuum vessel having an opening provided with a seal; and

a hollow needle connectable with said another end of said artificial ureter forming tube means and piercing said seal so as to communicate said artificial ureter tube means with the interior of said vacuum vessel.

9. An artificial kidney as defined in claim 8, wherein said suction means include a vacuum providing vessel, said artificial ureter tube means having one end connected with said urine outlet port and another end introduced into an interior of said vacuum vessel.

10. An artificial kidney as defined in claim 9, wherein said vacuum vessel is formed as an elastic vessel which is squeezable by a patient and restorable under elastic action of said vessel so as to form vacuum in its interior.

11. An artificial kidney as defined in claim 8, wherein said separate chamber has a permeable wall, said semi-permeable polymeric ultrafiltration-type membrane being arranged on said permeable wall.

12. An artificial kidney as defined in claim 11, wherein said permeable wall of said separate chamber is composed of porous material.

13. An artificial kidney as defined in claim 8;

and further comprising two porous filter elements, one of said filter elements being located between said inlet port and said inner space of said container and the other of said filter elements being located between said outlet port and said inner space of said container.

14. An artificial kidney as defined in claim 8;

and further comprising an arterial cannula implantable in an artery of a patient and a venous cannula implantable in a vein of a patient, said arterial cannula being connectable with said blood inlet port while said venous cannula is connectable with said blood outlet port of said container, said cannulae being also connectable with one another in an inoperative position of the artificial kidney system.