Cardiac pacer which compensates for effects of abrupt changes in heart rate

• US 5,545,185 A
• Filed: 12/23/1994
• Issued: 08/13/1996
• Est. Priority Date: 12/23/1994
• Status: Expired

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Stephen Denker
• Inventors: Denker, Stephen
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US08/363,139
• Time in Patent Office: 599 Days
• Field of Search: 607/14, 607/4, 607/9
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

Clinical studies of heart patients have demonstrated that ventricular tachyarrhythmia often is preceded by a foreshortened cardiac cycle length followed by a relatively long compensatory pause, thus producing in an abrupt short-to-long cycle length change. An implantable apparatus for preventing tachyarrhythmia measures the cardiac cycle length and detects the occurrence of a foreshortened cardiac cycle length more than a predefined amount between consecutive cycles. When a normal heart beat does not occur within a predefined period of time after such an abrupt change in cycle length, the resulting compensatory pause is eliminated by a cardiac pacer applying an appropriately timed electrical pulse to produce a contraction of the heart. The apparatus also includes a defibrillator to shock the heart in the event that the preventive pacing is not effective.

Claims

1. A method of preventing tachycardia comprising the steps of:

selecting threshold value for a change in heart cycle length from one heart cycle to a subsequent heart cycle;

selecting a time period, which is longer than the subsequent heart cycle;

measuring heart cycle lengths of an animal;

deriving a change in the heart cycle length from one heart cycle to a subsequent heart cycle;

comparing the change in the heart cycle length to the threshold value to detect when the heart cycle length decreases;

detecting when a new heart beat fails to occur within the time period which commences after the subsequent heart cycle;

if a new heart beat fails to occur within the time period after the change in heart cycle length exceeds the threshold value, commence treating the animal with a cardiac pacing technique to prevent tachycardia from occurring.

2. The method as recited in claim 1 wherein the step of deriving derives a change in heart cycle length between two consecutive heart cycles.

3. The method as recited in claim 1 wherein the cardiac pacing technique comprises applying an electrical pulse to a heart of the animal.

4. The method as recited in claim 1 wherein the cardiac pacing technique comprises:

applying an electrical pulse to a heart of the animal; and

applying subsequent electrical pulses to the heart of the animal whenever a heart beat fails to occur within the time period following a preceding electrical pulse.

5. The method as recited in claim 1 wherein the cardiac pacing technique comprises:

applying an electrical pulse to a heart of the animal; and

thereafter

a) increasing the time period to an increased time period;

b) applying a subsequent electrical pulse to the heart of the animal if a heart beat fails to occur within the increased time period.

6. The method recited in claim 5 wherein steps (a) and (b) are repeated until at least one spontaneous heart beat occurs.

7. The method as recited in claim 1 further comprising applying cardioversion/defibrillation to the animal, if after the a cardiac pacing technique, the animal fails have a normal heart rate.

8. The method as recited in claim 2 wherein a determination is made that the change in heart rate cycle length exceeds the threshold value when the subsequent heart cycle has a length which is 80 percent or less of a length of the one heart cycle.

9. The method as recited in claim 1 wherein comparing the change in the heart cycle length determines when the subsequent heart cycle length is shorter than the one heart cycle.

10. The method as recited in claim 1 wherein the time period is at least 1.2 times a length of the subsequent heart cycle.

11. The method as recited in claim 1 wherein the step of selecting a time period comprises multiplying a length of the subsequent heart cycle by a value that is greater than one.

12. The method as recited in claim 11 wherein the value is at least 1.20.

13. An apparatus for preventing tachycardia in a heart of an animal, said apparatus comprising:

a cardiac pacer which responds to a control signal by applying an electrical pulse to the animal to contract the heart;

a mechanism that measures the cardiac cycle length;

a detector coupled to said mechanism to produce a first indication when the cardiac cycle length decreases more than a predefined amount from one cycle to a subsequent cycle;

a processor which responds to the first indication by producing a second indication when a new heart beat fails to occur within a predefined time period after the subsequent cycle, where the predefined time period is longer than the subsequent cycle; and

an evaluator that responds to the second indication by sending the control signals to the cardiac pacer to perform a cardiac pacing technique to prevent tachycardia from occurring.

14. The apparatus as recited in claim 13 further comprising a telemetry circuit for altering the predefined amount.

15. The apparatus as recited in claim 13 further comprising a telemetry circuit for altering the predefined period of time.

16. The apparatus as recited in claim 13 further comprising a defibrillator which is responsive to said evaluator for applying a shock to the heart if a normal heart rhythm fails to occur after a given number of electrical pulses are applied by said cardiac pacer.

17. A method of preventing tachycardia comprising:

measuring a first length of a first heart cycle;

measuring a second length of a second heart cycle which occurs after the first heart cycle;

determining when the second length is shorter than the first length by at least a predefined amount;

deriving a time period as a function of the second length, where the time period is longer than the second length;

detecting when a new heart beat fails to occur within the time period following the second heart cycle and in response thereto producing an indication of such occurrence; and

responding to the indication by commencing treatment of the animal with a cardiac pacing technique to prevent tachycardia from occurring.

18. The method as recited in claim 17 wherein the second heart cycle consecutively follows the first heart cycle.

19. The method as recited in claim 17 wherein the cardiac pacing technique comprises:

(a) applying an electrical pulse to a heart of the animal; and

thereafter

(b) increasing the time period to an increased time period;

(c) applying a subsequent electrical pulse to the heart of the animal if a heart beat fails to occur within the increased time period; and

(d) repeating steps (b) and (c) until at least one spontaneous heart beat occurs.