Method for rapid temporal control of molecular transport across tissue
First Claim
1. A method for measuring a blood component content of blood, comprising the steps of:
- a) electroporating a portion of epidermis to cause an aqueous fluid to be directed through the electroporated epidermis to a surface of the epidermis; and
b) measuring the blood component content of the aqueous fluid for correlation with a known aqueous fluid blood component content associated with a known concentration of blood component in the blood, thereby measuring the blood component concentration of the blood.
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Abstract
A method is disclosed for treating tissue in response to a stimulus generated by the tissue. In one embodiment, the method transdermally treats an organism in response to a stimulus. In this embodiment, the medication is applied to epidermis of the organism, and the epidermis is electroporated in response to a stimulus, whereby the medication passes through the epidermis at a rate sufficient to alter the stimulus, thereby transdermally treating the organism. In another embodiment, the method measures a blood component content of blood. A portion of epidermis is electroporated to cause an aqueous fluid to be directed through an electroporated epidermis to a surface of the epidermis. Thereafter, the blood component content of the aqueous fluid is measured for correlation with a known aqueous fluid blood component content associated with a known concentration of blood component in the blood. The blood component concentration of the blood can thereby be measured. In still another embodiment, the method includes directing a medication to the tissue which can alter the stimulus when the tissue is electroporated, and electroporating the tissue in response to a stimulus, whereby the medication passes through the tissue in an amount sufficient to alter the stimulus, thereby treating the organism.
127 Citations
5 Claims
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1. A method for measuring a blood component content of blood, comprising the steps of:
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a) electroporating a portion of epidermis to cause an aqueous fluid to be directed through the electroporated epidermis to a surface of the epidermis; and b) measuring the blood component content of the aqueous fluid for correlation with a known aqueous fluid blood component content associated with a known concentration of blood component in the blood, thereby measuring the blood component concentration of the blood. - View Dependent Claims (2, 3, 4, 5)
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Specification