Method and apparatus for inducing the permeation of medication into internal tissue
First Claim
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1. An apparatus for selectively inducing the permeation of liquid to a targeted portion of internal tissue in the body of a patient comprising:
- at least one external electrode positioned outside of the patient'"'"'s body, said external electrode means adapted to extend circumferentially about a portion of the patient'"'"'s body;
a catheter having an elongate shaft, the catheter having proximal and distal ends;
means extending along the shaft for delivering said liquid from the proximal end to the distal region of the catheter;
means for emitting said liquid from the catheter;
an internal electrode carried by the catheter at the distal end of the catheter;
conductor means extending through the catheter shaft and being electrically connected to the internal electrode, the proximal end of the conductor being connectible to a source of electrical energy; and
means for inducing an electric field between said internal electrode and said at least one external electrode so that fluid emitted from the distal end of the catheter will flow in a direction extending from the internally placed electrode outwardly toward the external electrode.
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Abstract
A method and apparatus for selectively treating a targeted portion of internal body tissue of a patient by providing an internal electrode at a point adjacent the tissue to be treated and electrodes external to the patient'"'"'s body. Fluid containing Ionic molecules is supplied to a location between the internal electrode and the external electrodes and an electric field radiating outwardly from the internal electrode to the external electrodes is created so that said fluid flows outwardly away from said internal electrode into the tissue to be treated.
123 Citations
10 Claims
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1. An apparatus for selectively inducing the permeation of liquid to a targeted portion of internal tissue in the body of a patient comprising:
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at least one external electrode positioned outside of the patient'"'"'s body, said external electrode means adapted to extend circumferentially about a portion of the patient'"'"'s body; a catheter having an elongate shaft, the catheter having proximal and distal ends; means extending along the shaft for delivering said liquid from the proximal end to the distal region of the catheter; means for emitting said liquid from the catheter; an internal electrode carried by the catheter at the distal end of the catheter; conductor means extending through the catheter shaft and being electrically connected to the internal electrode, the proximal end of the conductor being connectible to a source of electrical energy; and means for inducing an electric field between said internal electrode and said at least one external electrode so that fluid emitted from the distal end of the catheter will flow in a direction extending from the internally placed electrode outwardly toward the external electrode.
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2. An apparatus as defined in claim 2 wherein the balloon is formed from a substantially inelastic material.
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4. A catheter for selectively inducing the permeation of liquid to a targeted portion of internal tissue in the body of a patient comprising:
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an elongate shaft having proximal and distal ends; means extending along the shaft for delivering said liquid from the proximal end of the catheter to the distal region of the catheter; a flexible, inflatable balloon mounted to the distal end of the catheter shaft, the balloon formed from a substantially inelastic material, the balloon having a plurality of pores formed therethrough to enable the liquid to flow out of the pores; an internal electrode carried by the catheter at the distal end of the catheter; conductor means extending through the catheter shaft and being electrically connected to the internal electrode, the proximal end of the conductor being connectible to a source of electrical energy. - View Dependent Claims (3, 5)
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6. An apparatus for selectively inducing the permeation of liquid to a targeted portion of a blood vessel in the body of a patient comprising:
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at least one external electrode adapted to be positioned outside of the patient'"'"'s body; a catheter having an elongated flexible shaft dimensioned for insertion into the human vascular system, the catheter having proximal and distal ends, means extending along the shaft for delivering said liquid from the proximal to the distal region of the catheter and for emitting said liquid from the catheter; an internal electrode carried by the catheter at the distal end of the catheter; a plurality of external electrodes adapted to be positioned circumferentially about a portion of the patient'"'"'s body; conductor means extending through the catheter shaft and being electrically connected to the internal electrode, the proximal end of the conductor being connectible to a source of electrical energy; and means for inducing an electric field between said internal electrode and said at least one external electrode so that fluid emitted from the distal end of the catheter will flow in a direction extending from the internally placed electrode outwardly toward the external electrode. - View Dependent Claims (7, 8)
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9. A catheter for selectively inducing the permeation of liquid to a targeted portion of a blood vessel in the body of a patient comprising:
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an elongated flexible shaft dimensioned for insertion into the human vascular system, said shaft having proximal and distal ends; means extending along the shaft for delivering said liquid from the proximal end of the catheter to the distal region of the catheter; a flexible, inflatable balloon mounted to the distal end of the catheter shaft the balloon is formed from a substantially inelastic material and has a plurality of pores formed therethrough to enable the liquid to flow out of the pores; an internal electrode carried by the catheter at the distal end of the catheter; and conductor means extending through the catheter shaft and being electrically connected to the internal electrode, the proximal end of the conductor being connectible to a source of electrical energy. - View Dependent Claims (10)
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Specification