Cardiac wall motion-based automatic capture verification system and method

• US 5,549,652 A
• Filed: 11/15/1993
• Issued: 08/27/1996
• Est. Priority Date: 11/15/1993
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Moberg, Sheldon B., McClure, Kelly H.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US08/152,659
• Time in Patent Office: 1,016 Days
• Field of Search: 607/5, 607/6, 607/7, 607/8, 607/28, 607/27, 607/11
• US Class Current: 607/28
• CPC Class Codes: A61N 1/36578 controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

An improved implantable cardiac stimulating device that performs cardiac wall motion-based automatic capture verification system is provided. Pacing pulses of varying energy content are administered to a patient'"'"'s heart, and the response of the patient'"'"'s heart is sensed by a cardiac wall motion sensor. The cardiac wall motion sensor provides a signal which is analyzed to determine the patient'"'"'s capture threshold, defined as the minimum amount of electrical stimulation required to evoke a cardiac contraction. The device then sets the amount of electrical stimulation at a level safely above the measured capture threshold. Capture verification may be performed at predetermined time intervals, on demand, or upon the occurrence of a significant cardiac event. Capture verification can also be performed on every pacing pulse delivered by the implantable cardiac stimulating device.

Claims

1. An implantable cardiac stimulating device for administering pacing pulses to cardiac tissue through an implantable stimulation lead, the device comprising:

a pacing pulse generator for generating the pacing pulses;

input circuitry for receiving a signal representative of cardiac wall motion; and

control circuitry, coupled to the pacing pulse generator and the input circuitry, for regulating the pacing pulse generator and for evaluating the signal representative of cardiac wall motion to determine when the pacing pulses evoke cardiac contractions.

2. The implantable cardiac stimulating device of claim 1, wherein:

the signal representative of cardiac wall motion is a cardiac wall acceleration signal; and

the input circuitry comprises means for receiving the cardiac wall acceleration signal.

3. The implantable cardiac stimulating device of claim 2, wherein the control circuitry further comprises:

means for detecting an excursion in the cardiac wall acceleration signal within a predetermined period of time following delivery of a selected pacing pulse, the excursion indicating that the selected pacing pulse evoked a cardiac contraction.

4. The implantable cardiac stimulating device of claim 1, wherein the control circuitry comprises:

means for adjusting an amount of electrical stimulation provided by the pacing pulses in response to an indication present in the signal representative of cardiac wall motion that a preceding pacing pulse did not evoke a cardiac contraction.

5. The implantable cardiac stimulating device of claim 4, wherein the control circuitry further comprises:

means for increasing the amount of electrical stimulation provided by the pacing pulses by a predetermined amount following every pacing pulse that does not evoke a cardiac contraction.

6. The implantable cardiac stimulating device of claim 1, wherein the control circuitry comprises:

means for determining a minimum amount of electrical stimulation that evokes a cardiac contraction.

7. The implantable cardiac stimulating device of claim 6, wherein the means for determining a minimum amount of electrical stimulation comprises:

means for decreasing an amount of electrical stimulation provided by the pacing pulses from a sufficient amount of electrical stimulation known to evoke a cardiac contraction until the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

8. The implantable cardiac stimulating device of claim 7, wherein the means for decreasing the amount of electrical stimulation provided by the pacing pulses comprises:

means for decrementing the amount of electrical stimulation provided by the pacing pulses from the sufficient amount of electrical stimulation by a predetermined amount until the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

9. The implantable cardiac stimulating device of claim 8, wherein the control circuitry further comprises:

means for resetting the amount of electrical stimulation provided by the pacing pulses to the minimum amount of electrical stimulation that evokes a cardiac contraction after the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

10. The implantable cardiac stimulating device of claim 9, wherein the control circuitry further comprises:

means for adding a safety margin to the minimum amount of electrical stimulation.

11. The implantable cardiac stimulating device of claim 7, wherein the control circuitry further comprises:

means for dithering a rate at which the pacing pulses are delivered.

12. The implantable cardiac stimulating device of claim 6, wherein the control circuitry further comprises:

means for determining the minimum amount of electrical stimulation at predetermined time intervals.

13. The implantable cardiac stimulating device of claim 6, further comprising:

means for programming the minimum amount of electrical stimulation.

14. The implantable cardiac stimulating device of claim 6, wherein:

the implantable cardiac stimulating device further comprises a high energy shock generator, coupled to the control circuitry, for administering therapeutic shocks through shocking electrodes; and

the control circuitry further comprises means for determining the minimum amount of electrical stimulation after a therapeutic shock is administered.

15. The implantable cardiac stimulating device of claim 1, wherein the control circuitry comprises:

means for distinguishing cardiac asystole from ventricular fibrillation.

16. The implantable cardiac stimulating device of claim 15, wherein the means for distinguishing cardiac asystole from ventricular fibrillation comprises:

means for causing the pacing pulse generator to generate a test pacing pulse during a period when the signal representative of cardiac wall motion indicates an occurrence of an undetermined one of cardiac asystole and ventricular fibrillation; and

means for monitoring the signal representative of cardiac wall motion for a predetermined period of time following delivery of the test pacing pulse to detect an excursion representing a cardiac contraction, the excursion being indicative of cardiac asystole and an absence of the excursion being indicative of ventricular fibrillation.

17. The implantable cardiac stimulating device of claim 15, further comprising a high energy shock generator, coupled to the control circuitry, for administering a therapeutic shock through shocking electrodes when the control circuitry detects ventricular fibrillation.

18. An implantable system for administering pacing therapy to cardiac tissue in accordance with a patient'"'"'s capture threshold, the system comprising:

a cardiac wall motion sensor for providing a signal representative of cardiac wall motion;

a pacing pulse generator;

pacing electrodes for delivering pacing pulses generated by the pacing pulse generator to cardiac tissue; and

control circuitry for evaluating the signal representative of cardiac wall motion to determine the patient'"'"'s capture threshold and for causing the pacing pulse generator to generate pacing pulses that provide an amount of electrical stimulation determined in accordance with the patient'"'"'s capture threshold.

19. The implantable system of claim 18, wherein the signal representative of cardiac wall motion is a cardiac wall acceleration signal.

20. The implantable system of claim 19, wherein the control circuitry comprises:

means for detecting an excursion in the cardiac wall acceleration signal within a predetermined period of time following delivery of a selected pacing pulse, the excursion indicating that the selected pacing pulse provided an amount of electrical stimulation that exceeded the patient'"'"'s capture threshold.

21. The implantable system of claim 18, wherein the control circuitry comprises:

means for adjusting the amount of electrical stimulation provided by the pacing pulses in response to an indication present in the signal representative of cardiac wall motion that a preceding pacing pulse did not evoke a cardiac contraction.

22. The implantable system of claim 21, wherein the control circuitry further comprises:

means for increasing the amount of electrical stimulation provided by the pacing pulses by a predetermined amount following every pacing pulse that does not evoke a cardiac contraction.

23. The implantable system of claim 18, wherein the control circuitry comprises:

means for determining a minimum amount of electrical stimulation that evokes a cardiac contraction.

24. The implantable system of claim 23, wherein the means for determining a minimum amount of electrical stimulation comprises:

means for decreasing an amount of electrical stimulation provided by the pacing pulses from a sufficient amount of electrical stimulation known to evoke a cardiac contraction until the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

25. The implantable system of claim 24, wherein the means for decreasing the amount of electrical stimulation provided by the pacing pulses comprises:

means for decrementing the amount of electrical stimulation provided by the pacing pulses from the sufficient amount of electrical stimulation by a predetermined amount until the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

26. The implantable system of claim 25, wherein the control circuitry further comprises:

means for resetting the amount of electrical stimulation provided by the pacing pulses to the minimum amount of electrical stimulation that evokes a cardiac contraction after the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

27. The implantable system of claim 26, wherein the control circuitry further comprises:

means for adding a safety margin to the minimum amount of electrical stimulation.

28. The implantable system of claim 24, wherein the control circuitry further comprises:

means for dithering a rate at which the pacing pulses are delivered.

29. The implantable system of claim 23, wherein the control circuitry further comprises:

means for determining the minimum amount of electrical stimulation at predetermined time intervals.

30. The implantable system of claim 23, further comprising a telemetry circuit, coupled to the control circuitry, for receiving an instruction from an external programmer that causes the control circuitry to determine the minimum amount of electrical stimulation.

31. The implantable system of claim 23, wherein:

the implantable system further comprises a high energy shock generator for administering therapeutic shocks through shocking electrodes; and

the control circuitry further comprises means for determining the minimum amount of electrical stimulation after a therapeutic shock is administered.

32. The implantable system of claim 18, wherein the control circuitry comprises:

means for distinguishing cardiac asystole from ventricular fibrillation.

33. The implantable system of claim 32, wherein the means for distinguishing cardiac asystole from ventricular fibrillation comprises:

means for causing the pacing pulse generator to generate a test pacing pulse during a period when the signal representative of cardiac wall motion indicates an occurrence of an undetermined one of cardiac asystole and ventricular fibrillation; and

means for monitoring the signal representative of cardiac wall motion for a predetermined period of time following delivery of the test pacing pulse to detect an excursion representing a cardiac contraction, the excursion being indicative of cardiac asystole and an absence of the excursion being indicative of ventricular fibrillation.

34. The implantable system of claim 32, further comprising a high energy shock generator, coupled to the control circuitry, for administering a therapeutic shock through shocking electrodes when the control circuitry detects ventricular fibrillation.

35. A method of regulating an amount of electrical stimulation provided by pacing pulses delivered to cardiac tissue from an implantable cardiac stimulating device in accordance with a patient'"'"'s capture threshold, comprising the steps of:

generating a signal representative of cardiac wall motion;

evaluating the signal representative of cardiac wall to determine the patient'"'"'s capture threshold; and

adjusting the amount of electrical stimulation provided by the pacing pulses in accordance with the patient'"'"'s capture threshold.

36. The method of claim 35, wherein the generating step comprises the step of generating a cardiac wall acceleration signal.

37. The method of claim 36, wherein the evaluating step comprises the step of:

detecting an excursion in the cardiac wall acceleration signal within a predetermined period of time following delivery of a selected pacing pulse, the excursion indicating that the selected pacing pulse provided an amount of electrical stimulation that exceeded the patient'"'"'s capture threshold.

38. The method of claim 35, wherein the adjusting step comprises the step of:

increasing the amount of electrical stimulation provided by the pacing pulses by a predetermined amount following every pacing pulse that does not exceed the patient'"'"'s capture threshold.

39. The method of claim 35, wherein the adjusting step comprises the step of:

decreasing the amount of electrical stimulation provided by the pacing pulses from a sufficient amount of electrical stimulation known to evoke a cardiac contraction until the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

40. The method of claim 39, wherein the decreasing step comprises the step of:

decrementing the amount of electrical stimulation provided by the pacing pulses from the sufficient amount of electrical stimulation by a predetermined amount until the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

41. The method of claim 40, wherein the adjusting step further comprises the step of:

resetting the amount of electrical stimulation provided by the pacing pulses to an amount of electrical stimulation that exceeds the patient'"'"'s capture threshold after the signal representative of cardiac wall motion indicates a failure of a pacing pulse to evoke a cardiac contraction.

42. The method of claim 41, wherein the adjusting step further comprises the step of:

adding a safety margin to the minimum amount of electrical stimulation.

43. An implantable cardiac stimulating system for distinguishing cardiac asystole from ventricular fibrillation, comprising:

means for generating a signal representative of cardiac wall motion;

means for delivering electrical stimulation to cardiac tissue during a period when the signal representative of cardiac wall motion indicates an undetermined one of cardiac asystole and ventricular fibrillation, the electrical stimulation being sufficient to evoke a cardiac contraction during cardiac asystole; and

means for monitoring the signal representative of cardiac wall motion for a predetermined period of time following delivery of the electrical stimulation to detect an excursion representing a cardiac contraction, the excursion being indicative of cardiac asystole and an absence of the excursion being indicative of ventricular fibrillation.

44. The system of claim 43, wherein the means for generating a signal representative of cardiac wall motion comprises an accelerometer.

45. A method of distinguishing cardiac asystole from ventricular fibrillation, comprising the steps of:

generating a signal representative of cardiac wall motion;

delivering electrical stimulation to cardiac tissue during a period when the signal representative of cardiac wall motion indicates an undetermined one of cardiac asystole and ventricular fibrillation, the electrical stimulation being sufficient to evoke a cardiac contraction during cardiac asystole; and

monitoring the signal representative of cardiac wall motion for a predetermined period of time following delivery of the electrical stimulation to detect an excursion representing a cardiac contraction, the excursion being indicative of cardiac asystole and an absence of the excursion being indicative of ventricular fibrillation.

46. An implantable cardiac stimulating device for administering pacing pulses to cardiac tissue through an implantable stimulation lead, the device comprising:

a pacing pulse generator for generating the pacing pulses;

a cardiac wall acceleration sensor for producing a cardiac wall acceleration signal corresponding to a mechanical cardiac contraction;

detecting means for detecting the absence of a cardiac wall acceleration signal corresponding to loss of capture;

control circuitry, coupled to the pacing pulse generator and the detecting means, for controlling the pacing pulse generator and for automatically increasing an amount of electrical stimulation energy provided by the pacing pulses whenever the cardiac wall acceleration signal indicates loss of capture.

47. The implantable cardiac stimulating device of claim 46, wherein the control circuitry further comprises:

means for automatically detecting capture threshold.

48. The implantable cardiac stimulating device of claim 47, wherein the control circuitry further comprises:

means for automatically adjusting the amount of electrical stimulation provided by the pacing pulses to a safety margin above the detected capture threshold.