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Compounds effective in the treatment of circadian rhythms and related disorders, the novel pharmaceutical preparations and novel method of application

  • US 5,552,428 A
  • Filed: 02/15/1994
  • Issued: 09/03/1996
  • Est. Priority Date: 06/24/1992
  • Status: Expired due to Fees
First Claim
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1. A compound having the ability to combat chronopathology of jet lag or delayed sleep phase syndrome of the formula:

  • ##STR7## wherein a) R=isopropyl R1 =CH3 R2 =Hb) R=cyclohexyl R1 =CH3 R2 =Hc) R=methyl R1 =cyclopropyl R2 =Hd) R=phenyl R1 =cyclopropyl R2 =He) R=Br R1 =cyclopropyl R2 =Hf) R=Br R1 =CH3 R2 =Br(g) R=I R1 =cyclopropyl R2 =Hor(h) R=Br R1 =CH3 R2 =H.

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