Method and apparatus for ultrasound medical treatment

• US 5,553,618 A
• Filed: 03/14/1994
• Issued: 09/10/1996
• Est. Priority Date: 03/12/1993
• Status: Expired due to Term

• Current Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Original Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: Okamoto, Kazuya, Suzuki, Takuji, Aida, Satoshi, Fujimoto, Katsuhiko, Izumi, Mamoru, Shibata, Mariko, Ishibashi, Yoshiharu, Saitoh, Shiroh
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US08/209,528
• Time in Patent Office: 911 Days
• Field of Search: 128/653.1, 128/653.2, 128/660.03, 601/2-4, 607/97
• US Class Current: 600/411
• CPC Class Codes: A61B 2017/00694 with means correcting for movement of or for synchronisation with the body
• CPC Class Codes: A61B 2017/00707 Dummies, phantoms; Devices simulating patient or parts of patient
• CPC Class Codes: A61B 2017/00716 simulating physical properties
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/504 with a counterweight
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 6/506 for diagnosis of nerves
• CPC Class Codes: A61B 8/00 Diagnosis using ultrasonic, sonic or infrasonic waves imaging of objects using sonar G01S15/00
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: G01R 33/28 Details of apparatus provided for in groups G01R33/44 - G01R33/64
• CPC Class Codes: G01R 33/4804 Spatially selective measurement of temperature or pH

Abstract

An ultrasound medical treatment system capable of determining the hot spot at high spatial resolution, and preventing the displacement of the hot spot from the focal point. In the system, the imaging device for obtaining image data of a treatment portion containing a treatment target and an irradiation device for applying radiation onto the treatment target are controlled in such a manner that the imaging device is controlled to obtain hot spot detection image data after the irradiation device is controlled to apply radiation at a prescribed level, so that a hot spot indicating a change due to a temperature change caused by the radiation at the prescribed level can be detected from the hot spot detection image data. The irradiation device is then controlled to apply a treatment radiation at a treatment level higher than the prescribed level according to the detected hot spot.

Claims

1. A medical treatment apparatus, comprising:

an imaging device to obtain image data of a treatment portion containing a treatment target;

an irradiation device to apply radiation onto the treatment target; and

a control device to control said imaging device and said irradiation device, said control device controlling said irradiation device to apply the radiation at a prescribed level and then controlling said imaging device to obtain hot spot detection image data, said control device detecting from the hot spot detection image data a hot spot indicating a change due to a temperature change caused by the radiation at the prescribed level, and said control device controlling said irradiation device to adjust a focal point of said irradiation device according to the detected hot spot and applying treatment radiation at a treatment level higher than the prescribed level.

2. The apparatus of claim 1, wherein said control device controls said imaging device to obtain reference image data before said irradiation device applies the radiation at the prescribed level, and

said control device detects the hot spot by comparing the hot spot detection image data with the reference image data.

3. The apparatus of claim 1, wherein said control device obtains the hot spot by extracting a portion of the hot spot detection image data that exceeds a prescribed threshold for said change due to the temperature change.

4. The apparatus of claim 1, wherein said control device controls said irradiation device to apply the radiation at the prescribed level so as not to damage the treatment target.

5. The apparatus of claim 4, wherein said control device controls said irradiation device to apply the radiation at the prescribed level for which a survival rate defined by the following equation is greater than a prescribed value:

##EQU2## where T.sub.φ

is a temperature before the radiation, Δ

T(t) is a time profile of a temperature change, Ea is an empirical activation energy, A is a proportional constant, R is a gas constant, and S is the survival rate.

6. A method of medical treatment, comprising the steps of:

applying radiation at a prescribed level onto a treatment target, said applying step being carried out by an irradiation device;

obtaining hot spot detection image data of a treatment portion containing the treatment target after said applying step, said obtaining step being carried out by an imaging device;

detecting a hot spot from the hot spot detection image data, the hot spot indicating a change due to a temperature change caused by the radiation at the prescribed level; and

carrying out a treatment by adjusting a focal point of said irradiation device in response to the detected hot spot and applying treatment radiation at a treatment level higher than the prescribed level.

7. The method of claim 6, further comprising the step of obtaining reference image data before said applying step, and

wherein said detecting step detects the hot spot by comparing the hot spot detection image data with the reference image data.

8. The method of claim 6, wherein said detecting step detects the hot spot by extracting a portion of the hot spot detection image data exceeding a prescribed threshold for said change due to the temperature change caused by said applying step.

9. The method of claim 6, wherein the prescribed level at which the radiation is applied at said applying step is a level that does not damage the treatment target.

10. The method of claim 9, wherein the prescribed level at which the radiation is applied at said applying step is a level for which a survival rate defined by the following equation is greater than a prescribed value:

##EQU3## where T.sub.φ

is a temperature before the radiation, Δ

T(t) is a time profile of a temperature change, Ea is an empirical activation energy, A is a proportional constant, R is a gas constant, and S is the survival rate.