Vascular prosthesis for the substitution or internal lining of blood vessels of medium or large diameter and device for its application

• US 5,554,183 A
• Filed: 01/13/1995
• Issued: 09/10/1996
• Est. Priority Date: 01/19/1994
• Status: Expired due to Term

• Current Assignee: Stefano Nazari
• Original Assignee: Stefano Nazari
• Inventors: Nazari, Stefano
• Primary Examiner(s): Milano, Michael J.
• Application Number:
  US08/372,746
• Time in Patent Office: 606 Days
• Field of Search: 623/1, 623/12, 604/96, 604/104-107, 606/108, 606/140, 606/157, 606/158, 606/198, 606/194, 606/191
• US Class Current: 623/1.49
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/9517 handle assemblies therefor
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/828 Means for connecting a plurality of stents allowing flexibility of the whole structure
• CPC Class Codes: A61F 2002/9505 having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
• CPC Class Codes: A61F 2002/9511 the retaining means being filaments or wires

Abstract

Vascular prosthesis for the substitution or internal lining of blood vessels of medium and large diameter and to a device for its application which includes a tubular body of biocompatible material that is associated with, at least at one longitudinal end, at least one body at annular development, that is disposed substantially coaxial to the tubular body and that is radially expandable for the engagement of the tract of the tubular body, which contains the body at annular development, against the inner walls of a blood vessel proximal to the segment of the vessel to be substituted, or internally lined, with the prosthesis. The body at annular development includes at least one loop of at least one wire elastically flexible, which is slideably mounted on a support associated to a lateral portion of the tubular body. This wire is slideable with respect to the support mentioned before to vary the amplitude of the loop and tools are predisposed to contrast the wire sliding in respect to the support in order to maintain the expansion or contraction, given to the loop by means of the controlled sliding of the wire relatively to the support, at ceasing of the force generating the sliding.

Claims

1. Vascular prosthesis for substitution or internal lining of a segment of a blood vessel of medium or large diameter, comprising

a tubular body made of biocompatible material, said tubular body defining a lateral wall, a first and a second longitudinal end thereof and a longitudinal axis thereof;

at least one radially expandable body disposed substantially coaxial to said tubular body and perimetrically connected to said tubular body, said expandable body comprising

a support extending longitudinally along an axis between a first and a second longitudinal end thereof, said axis being substantially parallel to the axis of the tubular body, said support having a plurality of lateral holes, said plurality of lateral holes including at least a first lateral hole and a second lateral hole proximal to said first lateral hole, and at least a third lateral hole and a forth lateral hole proximal to said third hole, said third and fourth holes being longitudinally spaced with respect to said first and second holes; and

at least one elastically flexible wire slidingly mounted on said support for radial expansion and contraction of said expandable body, said wire entering the support through said first longitudinal end thereof, said wire then coming out from the support through said first lateral hole and reentering the support through said third lateral hole so as to define a first tract of said wire inclined with respect to a plane perpendicular to said axis of said tubular body and a second tract of said wire in a plane perpendicular to said axis of said tubular body, said wire further coming out again from the support through said forth lateral hole and reentering the support through said second lateral hole so as to define a third tract of said wire substantially in the same plan as the second tract, and a forth tract of said wire inclined with respect to a plan perpendicular to the axis of said tubular body, said second tract and said third tract forming substantially an annular loop, said wire coming out then from the support through said first longitudinal end thereof, thereby expansion and contraction of said tubular body is obtained when said wire slides with respect to said support, said wire being frictionally engaged to said support in said first, second, third and fourth lateral hole,

said expandable body being connected to said tubular body by repeated passages of said wire along said first, second, third and forth tract through the wall of said tubular body, thereby a radial expansion of said tubular body is obtained when said expandable body is expanded, said expandable body being disposed at said first end of said tubular body.

2. Vascular prosthesis, according to claim 1, wherein said expandable body comprises at least two wires, each of said at least two wires defining a first tract of said wire inclined with respect to a plane perpendicular to said axis of said tubular body, a second tract of said wire in a plane perpendicular to said axis of said tubular body, a third tract of said wire substantially in the same plan as the second tract, and a forth tract of said wire inclined with respect to a plan perpendicular to the axis of said tubular body, said second tract and said third tract forming substantially an annular loop, said first, second, third and forth tracts of said first wire being longitudinally spaced from and substantially parallel to said first, second, third and forth tracts of said second wire.

3. Vascular prosthesis, according to claim 2, comprising means for positioning said first wire in respect to said second wire.

4. Vascular prosthesis, according to claim 3, wherein said means for positioning include segments of wire connecting said annular loops defined by said first and second wire in order to keep them in substantially parallel planes.

5. Vascular prosthesis, according to claim 2, wherein ends of said first and second wire extending externally from said first end of said support are jointed to a cylinder for maneuvering said wires, said cylinder being mobile along an axis thereof, said axis being parallel to said axis of said support, thereby causing a sliding of said wire with respect to said support to obtain a first, second, third and fourth tract amplitude variation thereby allowing to expand and contract said expandable body and said tubular body.

6. Vascular prosthesis, according to claim 5, wherein said cylinder and a portion of said wire extending from said cylinder to said support are disposed externally to said tubular body.

7. Vascular prosthesis, according to claim 1, wherein said support is substantially cylindric.

8. Vascular prosthesis, according to claim 1, wherein said tubular body comprises a first portion disposed at said first end of said tubular body, and a second portion substantially coaxial with said first portion, said first portion being connected at an axial end of said second portion, said expandable body being connected to said first portion.

9. Vascular prosthesis, according to claim 1, wherein said wires are of harmonic stainless steel.

10. Vascular prosthesis for substitution or internal lining of a segment of a blood vessel of medium or large diameter, comprising

a tubular body made of biocompatible material, said tubular body defining a lateral wall, a first and a second longitudinal end thereof and a longitudinal axis thereof;

a first radially expandable body and a second radially expandable body, said first and second expandable body being disposed substantially coaxial to said tubular body and perimetrically connected to said tubular body, each of said first and second expandable body comprising

a support extending longitudinally along an axis between a first and a second longitudinal end thereof, said axis being substantially parallel to the axis of the tubular body, said support having a plurality of lateral holes, said plurality of lateral holes including at least a first lateral hole and a second lateral hole proximal to said first lateral hole, and at least a third lateral hole and a forth lateral hole proximal to said third hole, said third and fourth holes being longitudinally spaced with respect to said first and second holes; and

at least one elastically flexible wire slidingly mounted on said support for radial expansion and contraction of said expandable body, said wire entering the support through said first longitudinal end thereof, said wire then coming out from the support through said first lateral hole and reentering the support through said third lateral hole so as to define a first tract of said wire inclined with respect to a plane perpendicular to said axis of said tubular body and a second tract of said wire in a plane perpendicular to said axis of said tubular body, said wire further coming out again from the support through said forth lateral hole and reentering the support through said second lateral hole thereby forming a third tract of said wire substantially in the same plan as the second tract, and a forth tract of said wire inclined with respect to a plan perpendicular to the axis of said tubular body, said second tract and said third tract forming substantially an annular loop, said wire coming out then from the support through said first longitudinal end thereof, thereby expansion and contraction of said tubular body is obtained when said wire slides with respect to said support, said wire being frictionally engaged to said support in said first, second, third and fourth lateral hole, said first and second expandable body being connected to said tubular body by repeated passages of said wire along said first, second, third and forth tract through the wall of said tubular body, thereby a radial expansion of said tubular body is obtained when said first and second expandable body are expanded,

said first expandable body being connected to said tubular body in a first region of said tubular body proximal to said first longitudinal end of said tubular body and said second expandable body being connected to said tubular body in a second region of said tubular body proximal to said second end of said tubular body.

11. Vascular prosthesis, according to claim 10, wherein each of said first expandable body and said second expandable body comprises at least two wires, each of said at least two wires defining a first tract of said wire inclined with respect to a plane perpendicular to said axis of said tubular body, a second tract of said wire in a plane perpendicular to said axis of said tubular body, a third tract of said wire substantially in the same plan as the second tract, and a forth tract of said wire inclined with respect to a plan perpendicular to the axis of said tubular body, said second tract and said third tract forming substantially an annular loop, said first, second, third and forth tracts of said first wire being longitudinally spaced from and substantially parallel to said first, second, third and forth tracts of said second wire.

12. Vascular prosthesis, according to claim 11, comprising means for positioning said first wire in respect to said second wire.

13. Vascular prosthesis, according to claim 12, wherein said means for positioning include segments of wire connecting said annular loops defined by said first and second wire in order to keep them in substantially parallel planes.

14. Vascular prosthesis, according to claim 11, wherein ends of said first and second wire extending externally from said first end of said support are jointed to a cylinder for maneuvering said wires, said cylinder being mobile along an axis thereof, said axis being parallel to said axis of said support, thereby causing a sliding of said wire with respect to said support to obtain a first, second, third and fourth tract amplitude variation thereby allowing to expand and contract said expandable body and said tubular body.

15. Vascular prosthesis, according to claim 14, wherein said cylinder and a portion of said wires extending from said cylinder to said support are disposed externally to said tubular body.

16. Vascular prosthesis, according to claim 10, wherein said support is substantially cylindric.

17. Vascular prosthesis for substitution or internal lining of a segment of a blood vessel of medium or large diameter, comprising

a tubular body made of biocompatible material, said tubular body defining a lateral wall, a first and a second longitudinal end thereof and a longitudinal axis thereof;

a first radially expandable body and a second radially expandable body, said first and second expandable body being disposed substantially coaxial to said tubular body and perimetrically connected to said tubular body, each of said first and second expandable body comprising

a support extending longitudinally along an axis between a first and a second longitudinal end thereof, said axis being substantially parallel to the axis of the tubular body, said support having a plurality of lateral holes, said plurality of lateral holes including at least first lateral hole and a second lateral hole proximal to said first lateral hole, and at least a third lateral hole and a forth lateral hole proximal to said third hole, said third and fourth holes being longitudinally spaced with respect to said first and second holes; and

at least one elastically flexible wire slidingly mounted on said support for radial expansion and contraction of said expandable body, said wire entering the support through said first longitudinal end thereof, said wire then coming out from the support through said first lateral hole and reentering the support through said third lateral hole so as to define a first tract of said wire inclined with respect to a plane perpendicular to said axis of said tubular body and a second tract of said wire in a plane perpendicular to said axis of said tubular body, said wire further coming out again from the support through said forth lateral hole and reentering the support through said second lateral hole thereby forming a third tract of said wire substantially in the same plan as the second tract, and a forth tract of said wire inclined with respect to a plan perpendicular to the axis of said tubular body, said second tract and said third tract forming substantially an annular loop, said wire coming out then from the support through said first longitudinal end thereof, thereby expansion and contraction of said tubular body is obtained when said wire slides with respect to said support, said wire being frictionally engaged to said support in said first, second, third and fourth lateral hole, said first and second expandable body being connected to said tubular body by repeated passages of said wire along said first, second, third and forth tract through the wall of said tubular body, thereby a radial expansion of said tubular body is obtained when said first and second expandable body are expanded,

said first expandable body and said second expandable body being connected to said tubular body at said first longitudinal end of said tubular body, said support of said first expandable body being placed diametrically opposite to said support of said second expandable body.

18. Vascular prosthesis, according to claim 17, wherein each of said first expandable body and said second expandable body comprises at least two wires, each of said at least two wires defining a first tract of said wire inclined with respect to a plane perpendicular to said axis of said tubular body, a second tract of said wire in a plane perpendicular to said axis of said tubular body, a third tract of said wire substantially in the same plan as the second tract, and a forth tract of said wire inclined with respect to a plan perpendicular to the axis of said tubular body, said second tract and said third tract forming substantially an annular loop, said first, second, third and forth tracts of said first wire being longitudinally spaced from and substantially parallel to said first, second, third and forth tracts of said second wire.

19. Vascular prosthesis, according to claim 18, comprising means for positioning said first wire in respect to said second wire.

20. Vascular prosthesis, according to claim 19, wherein said means for positioning include segments of wire connecting said annular loops defined by said first and second wire in order to keep them in substantially parallel planes.

21. Vascular prosthesis, according to claim 18, wherein ends of said first and second wire extending externally from said first end of said support are jointed to a cylinder for maneuvering said wires, said cylinder being mobile along an axis thereof, said axis being parallel to said axis of said support, thereby causing a sliding of said wire with respect to said support to obtain a first, second, third and fourth tract amplitude variation thereby allowing to expand and contract said expandable body and said tubular body.

22. Vascular prosthesis, according to claim 21, wherein said cylinder and a portion of said wires extending from said cylinder to said support are disposed externally to said tubular body.

23. Vascular prosthesis, according to claim 17, wherein said support is substantially cylindric.