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Method for the long term reduction of body fat stores, insulin resistance, hypersinsulinemia and hyperglycemia in vertebrates

  • US 5,554,623 A
  • Filed: 05/26/1994
  • Issued: 09/10/1996
  • Est. Priority Date: 05/10/1988
  • Status: Expired due to Term
First Claim
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1. A method for modifying and regulating at least one of lipid and glucose metabolism in a vertebrate animal or human subject in need of such treatment comprising:

  • administering a prolactin stimulator to said subject on a timed daily basis at a predetermined time of day in a dosage amount sufficient to increase hormonal prolactin level in the blood of said subject; and

    continuing said administration for a period of time sufficient to modify and reset on a long-term basis the subject'"'"'s daily prolactin cycle to cause it to mimic the peak of the daily prolactin cycle of a lean healthy member of the same species, thereby achieving in said subject at least one of the following modifications in lipid and glucose metabolism;

    decrease in insulin resistance, reduction in fat stores, suppression of hyperinsulinemia and reduction of hyperglycemia.

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