Method and apparatus for treating stenosis or other constriction in a bodily conduit

• US 5,556,389 A
• Filed: 03/31/1994
• Issued: 09/17/1996
• Est. Priority Date: 03/31/1994
• Status: Expired due to Fees

• Current Assignee: Interventional Therapies L L C
• Original Assignee: Samuel F. Liprie
• Inventors: Liprie, Samuel F.
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): SMITH, CHALIN A
• Application Number:
  US08/220,681
• Time in Patent Office: 901 Days
• Field of Search: 604/96, 604/101, 604/264, 604/265, 604/280, 604/165, 604/169, 604/19, 604/20, 604/246, 604/247, 604/249, 600/191, 600/192, 600/194, 600/3, 600/7, 128/657, 128/772
• US Class Current: 604/264
• CPC Class Codes: A61B 2017/22002 preventing restenosis
• CPC Class Codes: A61M 2025/1047 having centering means, e.g. balloons having an appropriate shape
• CPC Class Codes: A61M 2025/1079 having radio-opaque markers in the region of the balloon
• CPC Class Codes: A61M 2025/1086 having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
• CPC Class Codes: A61M 2025/1093 having particular tip characteristics
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: A61M 25/104 used for angioplasty
• CPC Class Codes: A61N 2005/1003 having means for centering a radioactive source within the lumen, e.g. balloons
• CPC Class Codes: A61N 5/1002 Intraluminal radiation therapy

Abstract

An apparatus and method for treating an occlusion or constriction, such as a stenosis in a blood vessel or other conduit in the body, as well as an apparatus and method for treating a tumor or cancerous area occurring around a conduit or duct in the body. The apparatus includes a catheter provided with a ribbed balloon encircling a portion near its distal end. When inserted into the body over a guide wire and transported to the site of the stenosis, the balloon is inflated one or more times and, due to the ribbed balloon, blood perfuses around the catheter during the treatment. A radioactive source of material is inserted through the catheter to the site of the stenosis or cancer where it is maintained in position for a period of time to reduce the occurrence of re-stenosis or cancer. A guide wire provided with a removable core can be utilized to properly maneuver the catheter to the site of the stenosis or cancer.

Claims

1. A device for treating an occlusion or a constriction in a vessel or other conduit in the body, comprising:

a flexible, elongated, hollow catheter having a distal end and a proximal end, said catheter provided with a first aperture at said distal end and a second aperture at the proximal end;

a ribbed balloon having a distal end and a proximal end encircling a portion of the catheter proximate to said distal end;

a first conduit extending along the exterior surface of said catheter from said proximal end of said catheter to said ribbed balloon;

a source for inflating said ribbed balloon connected to conduit for inflating said ribbed balloon pretreating the inclusion or constriction while allowing liquid to flow around a portion of said ribbed balloon with said ribbed balloon is inflated;

a flexible, elongated guide wire maneuvered to the site of the occlusion or constriction prior to said catheter being maneuvered to the site of the occlusion or constriction, wherein said guide wire travels through the interior of said catheter, said guide wire comprising a hollow conduit and a removable inner core; and

a means for injecting a contrast dye into the body for determining the location of said catheter and said guide wire in the body, wherein said means for injecting a contrast dye injects the contrast dye through said hollow conduit of said guide wire.

2. The device in accordance with claim 1, further including a sealing means and provided in the interior of said catheter between the portion of said catheter encircled by said ribbed balloon and said first aperture for preventing bodily fluids from entering a portion of said catheter, said sealing means consisting of a one-way valve provided with a flap and tensioned hinge which allows said guide wire to pass through.

3. The device in accordance with claim 2, wherein said one-way valve is provided with a funnel-shaped entrance to facilitate said guide wire passing through said one-way valve.

4. The device in accordance with claim 2, wherein said sealing means consists of a plurality of elastic membranes separated by a filter which allows said guide wire to pass through.

5. The device for treating an occlusion or a constriction in a vessel or other conduit in the body, comprising:

a flexible, elongated, hollow catheter having a distal end and a proximal end, said catheter provided with a first aperture at said distal end and a second aperture at said proximal end;

a ribbed balloon having a distal end and a proximal end encircling a portion of said catheter proximate to said distal end;

a first conduit extending along the exterior surface of said catheter from said proximal end of the catheter to said ribbed balloon;

a source for inflating said ribbed balloon connected to said conduit for inflating said ribbed balloon for treating the occlusion or constriction while allowing liquid to flow around a portion of said ribbed balloon when said ribbed balloon is inflated;

an elongated, flexible member having a proximal end and a distal end, said distal end of said flexible member provided with at least one radioactive source maneuvered to the site of the occlusion or constriction after said ribbed balloon has been inflated at least once;

a flexible, elongated guide wire maneuvered to the site of the occlusion or constriction prior to said catheter being maneuvered to the site of the occlusion or constriction, wherein said guide wire travels through the interior of said catheter, and is removed from the interior of said hollow catheter prior to said elongated, flexible member being inserted into said hollow catheter, said guide wire comprising a hollow conduit and inner core which is removed after said guide wire reaches the site of the occlusion or constriction; and

a mean for injecting a contrast dye into the body for determining the location of said catheter and said guide wire in the body, said means for injecting the contrast dye injects the contrast dye through said hollow conduit of said guide wire.

6. The device in accordance with claim 5, further including a sealing means provided in the interior of said catheter between the portion of said catheter encircled by said ribbed balloon and said first aperture for preventing bodily fluids from entering a portion of said catheter, said sealing means consisting of a one-way valve to be provided with a flap and tension hinge which allows said guide wire to pass through.

7. The device in accordance with claim 6, wherein said one-way valve is provided with a funnel-shaped entrance to facilitate said guide wire passing through said one-way valve.

8. The device in accordance with claim 6, wherein said sealing means consists of a plurality of elastic membranes separated by a filter which allows said guide wire to pass through.