Cardiac arrhythmia detection system for an implantable stimulation device and method

• US 5,560,369 A
• Filed: 09/22/1994
• Issued: 10/01/1996
• Est. Priority Date: 12/01/1992
• Status: Expired due to Term

• Current Assignee: Siemens Pacesetter, Inc. (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: McClure, Kelly H., Bornzin, Gene A.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/310,688
• Time in Patent Office: 740 Days
• Field of Search: 128/696, 128/697, 128/702, 128/704, 128/705, 128/708, 128/901, 128/902, 128/, 604/4, 604/5, 604/14, 604/27
• US Class Current: 600/518
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: Y10S 128/901 Suppression of noise in electric signal

Abstract

A cardiac event and arrhythmia detection system and method detects arrhythmic cardiac activity or other information from an electrogram signal of a heart. The system senses the electrogram signal through an electrogram lead, preliminarily processes the signal, and converts it to a plurality of discrete digital signals, each of which represents the magnitude of the electrogram signal at a prescribed sample time. The discrete digital signals are applied to both a cardiac event detector and a morphology detector. The morphology detector detects selected changes in the morphology (shape) of the electrogram signal, wherein such changes automatically control the sensitivity (gain and/or threshold) used to detect cardiac events. The occurrence of a prescribed amount of change in the detected morphology over time indicates the occurrence of a prescribed arrhythmic cardiac condition.

Claims

1. An implantable cardiac arrhythmia detection system for detecting the presence of rhythmic and arrhythmic cardiac activity in a heart, the system including an implantable lead that transmits an electrogram signal from the heart, the system comprising:

means, coupled to the implantable lead, for determining an average magnitude of the electrogram signal; and

means for detecting when the average magnitude exceeds a prescribed threshold, wherein a change less than a prescribed amount indicates the presence of rhythmic cardiac activity and a change greater than the prescribed amount indicates the presence of pathological arrhythmic cardiac activity in the heart.

2. The implantable system, as set forth in claim 1, wherein the determining means comprises:

means for determining an average magnitude for a prescribed portion of the electrogram signal.

3. The implantable system, as set forth in claim 2, wherein the determining means further comprises:

means for rectifying the electrogram signal; and

means for determining an average magnitude for the rectified electrogram signal.

4. The implantable system, as set forth in claim 2, wherein the determining means further comprises:

converting means for sampling and converting the electrogram signal from the implantable lead to a plurality of unsigned digitized samples;

counting means for counting each of the plurality of samples and providing as an output a number of samples; and

processing means for accumulating the magnitude of each of the unsigned digitized samples of the electrogram signal, and for dividing the accumulated magnitude by the number of samples.

5. The implantable system, as set forth in claim 2, wherein the determining means further comprises:

timing means for determining the prescribed portion of the electrogram signal, the prescribed portion corresponding to a quiescent portion of the electrogram;

converting means for sampling and converting the electrogram signal from the implantable lead to a plurality of unsigned digitized samples during the prescribed portion of the electrogram signal;

counting means for counting each of the plurality of samples and providing as an output a number of samples; and

processing means for summing the magnitude of each of the unsigned digitized samples of the electrogram signal during the prescribed portion, and for dividing the accumulated magnitude by the number of samples.

6. The implantable system, as set forth in claim 2, further comprising means for detecting at least one cardiac cycle, wherein the prescribed portion of the electrogram signal corresponds to the at least one cardiac cycle.

7. The implantable system, as set forth in claim 2, further comprising means for detecting a quiescent portion of the electrogram, wherein the prescribed portion of the electrogram signal corresponds to the quiescent portion of the electrogram.

8. The implantable system, as set forth in claim 7, wherein the means for detecting a quiescent portion of the electrogram comprises:

event detecting means for detecting the occurrence of an R-wave in the electrogram signal;

delay means for initiating a delay period following the detection of an R-wave; and

timing means for determining a prescribed time interval following the delay period, the prescribed time interval corresponding to a time interval in which R-waves are not expected to occur.

9. The implantable system of claim 2, wherein the means for detecting when the baseline signal exceeds a prescribed threshold comprises:

event detecting means for detecting the occurrence of an R-wave in the electrogram signal;

peak detecting means for detecting a peak value of the R-wave; and

means for determining the quotient of the peak value divided by the average baseline value and producing as an output an arrhythmia flag whenever the quotient exceeds a prescribed amount.

10. The implantable system, as set forth in claim 2, further comprising:

means for defining the prescribed portion of the electrogram signal as a portion of the electrogram signal which is expected to be quiescent.

11. The implantable system, as set forth in claim 2, further comprising:

means for defining the prescribed portion of the electrogram signal as a complete cardiac cycle containing the electrogram, wherein during normal sinus rhythm, the average magnitude over the entire cardiac cycle approximates the quiescent portion of the electrogram.

12. A method for detecting the presence of rhythmic cardiac activity and arrhythmic cardiac activity, comprising the steps of:

(a) sensing an electrogram signal;

(b) determining an average magnitude of the electrogram signal; and

(c) detecting a change in the average magnitude by a prescribed amount, a change less than the prescribed amount indicating the presence of rhythmic activity and a change greater than the prescribed amount indicating the presence of arrhythmic activity.