Subcutaneous drug delivery device
First Claim
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1. A subcutaneous drug delivery device comprising:
- a) a housing with a bore extending along a longitudinal axis of the housing and a track extending parallel to the bore, said track having an elongate housing slot extending along the longitudinal axis;
b) a piston having a distal end;
c) a cannula mounted concentric with the piston within the bore and extending along the longitudinal axis thereof with a distal end of the cannula extending beyond the distal end of the piston, the cannula having a cannula notch at the cannula distal end for supporting a drug, the cannula notch having a distal surface which extends distally outward and away from the housing to form an inclined surface upon which the drug can be pushed up for laterally ejecting the drug;
d) a driving member slideably engaged in said track for longitudinal movement therein, the driving member having a hole formed therein;
e) a piston drive pin for engaging the driving member hole for advancing the piston, the piston drive pin extending from the piston in a direction perpendicular to the longitudinal axis through the housing slot and the driving member hole;
such that, as the driving member is moved distally along the track toward the piston distal end, the hole in the driving member is engaged by the piston drive pin and the piston is extended until the distal end of the piston reaches the distal surface of the cannula notch whereupon the piston distally pushes the drug up the inclined distal surface of the cannula notch to eject the drug laterally from the cannula notch.
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Accused Products
Abstract
A subcutaneous drug delivery device having a driving member for advancing a piston, concentrically enclosed by a cannula, to deliver a drug pellet to a subcutaneous tissue site. The piston has a recessed distal platform upon which the pellet rests for delivery when the distal end of the piston is exposed beyond the cannula.
153 Citations
22 Claims
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1. A subcutaneous drug delivery device comprising:
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a) a housing with a bore extending along a longitudinal axis of the housing and a track extending parallel to the bore, said track having an elongate housing slot extending along the longitudinal axis; b) a piston having a distal end; c) a cannula mounted concentric with the piston within the bore and extending along the longitudinal axis thereof with a distal end of the cannula extending beyond the distal end of the piston, the cannula having a cannula notch at the cannula distal end for supporting a drug, the cannula notch having a distal surface which extends distally outward and away from the housing to form an inclined surface upon which the drug can be pushed up for laterally ejecting the drug; d) a driving member slideably engaged in said track for longitudinal movement therein, the driving member having a hole formed therein; e) a piston drive pin for engaging the driving member hole for advancing the piston, the piston drive pin extending from the piston in a direction perpendicular to the longitudinal axis through the housing slot and the driving member hole; such that, as the driving member is moved distally along the track toward the piston distal end, the hole in the driving member is engaged by the piston drive pin and the piston is extended until the distal end of the piston reaches the distal surface of the cannula notch whereupon the piston distally pushes the drug up the inclined distal surface of the cannula notch to eject the drug laterally from the cannula notch. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A subcutaneous drug delivery device comprising:
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a) a housing with a bore extending along a longitudinal axis of the housing and a track extending parallel to the bore, said track having an elongate housing slot extending along the longitudinal axis; b) a piston having a distal end; c) a cannula mounted concentric with the piston within the bore and extending along the longitudinal axis thereof with a distal end of the cannula extending beyond the distal end of the piston, the cannula having a cannula notch at the cannula distal end for supporting a drug, the cannula notch having a distal surface which extends distally outward and away from the housing to form an inclined surface upon which the drug can be pushed up for laterally ejecting the drug; d) a driving member slideably engaged in said track for longitudinal movement therein, the driving member having a hole formed therein; e) a piston drive pin for engaging the driving member hole for advancing the piston, the piston drive pin extending from the piston in a direction perpendicular to the longitudinal axis through the housing slot and the driving member hole; f) an outer tube mounted concentric with the cannula and extending along the longitudinal axis, the outer tube being secured to the housing and being capable of enclosing the cannula notch; g) an elongate driving member slot extending along the longitudinal axis, the driving member slot having a notch formed therein; and h) a cannula drive pin for engaging the notch in the driving member slot for advancing the cannula, the cannula drive pin extending through the housing slot and the driving member slot; such that, as the driving member is moved distally along the track toward the piston distal end, the notch in the driving member slot is engaged by the cannula drive pin and the hole in the driving member is engaged by the piston drive pin, the cannula and the piston being extended in unison until the cannula notch is extended beyond the outer tube, and as the driving member is extended further, the piston is extended until the distal end of the piston reaches the distal surface of the cannula notch whereupon the piston distally pushes the drug up the inclined distal surface of the cannula notch to eject the drug laterally from the cannula notch. - View Dependent Claims (8, 9, 10)
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11. A method for delivering a drug to a site within the body of an individual comprising:
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assembling a cannula concentrically about a piston along a longitudinal axis, the piston extending within a longitudinal bore of a housing for longitudinal movement along said bore, the cannula having a notch at a distal end of the cannula, the cannula notch having a distal surface; providing a drug within the cannula notch; mounting an outer tube concentrically about the cannula along the longitudinal axis, the outer tube being secured to the housing and being capable of enclosing the cannula notch; engaging a piston drive pin extending perpendicularly from the piston with a driving member having a hole formed therein, the driving member being mounted on a track in the housing for longitudinal movement, the track having an elongate housing slot; engaging a cannula drive pin extending perpendicularly from the cannula with the driving member, the cannula drive pin extending through the housing slot and through a driving member slot, the driving member slot having a notch formed therein; advancing the driving member along the track toward the piston distal end, such that the notch in the driving member slot is engaged by the cannula drive pin and the hole in the driving member is engaged by the piston drive pin, the cannula extending until the cannula notch is extended beyond the outer tube, the piston extending until the distal end of the piston reaches the distal surface of the cannula notch whereupon the piston pushes the drug against the distal surface of the cannula notch to eject the drug laterally from the cannula notch. - View Dependent Claims (12)
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13. A method for delivering a drug to a site within the body of an individual comprising:
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a) assembling a cannula concentrically about a piston along a longitudinal axis, the piston extending within a longitudinal bore of a housing for longitudinal movement along said bore, the cannula having a notch at a distal end of the cannula, the cannula notch having a distal surface; b) providing a drug within the cannula notch; c) mounting an outer tube concentrically about the cannula along the longitudinal axis, the outer tube being secured to the housing and being capable of enclosing the cannula notch; d) engaging a piston drive pin extending perpendicularly from the piston with a driving member having a hole formed therein, the driving member being mounted on a track in the housing for longitudinal movement, the track having an elongate housing slot; e) engaging a cannula drive pin extending perpendicularly from the cannula with the driving member, the cannula drive pin extending through the housing slot and through a driving member slot, the driving member slot having a notch formed therein; f) advancing the driving member along the track toward the piston distal end, such that the notch in the driving member is engaged by the cannula drive pin and the hole in the driving member is engaged by the piston drive pin, the cannula and the piston being extended in unison until the cannula notch is extended beyond the outer tube, and as the driving member is extended further, the piston is extended until the distal end of the piston reaches the distal surface of the cannula notch whereupon the piston pushes the drug against the distal surface of the cannula notch to eject the drug laterally from the cannula notch. - View Dependent Claims (14)
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15. A method for delivering a drug to a site within the body of an individual comprising:
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a) assembling a cannula concentrically about a piston along a longitudinal axis, the piston extending within a longitudinal bore of a housing for longitudinal movement along said bore, the cannula having a notch at a distal end of the cannula, the cannula notch having a distal surface which extends distally outward and away from the housing to form an inclined surface upon which drugs can be pushed up and laterally ejected; b) providing a drug within the cannula notch; c) engaging a piston drive pin extending perpendicularly from the piston with a driving member having a hole formed therein, the driving member being mounted on a track in the housing for longitudinal movement, the track having an elongate housing slot; d) advancing the driving member along the track toward the piston distal end, the hole in the driving member engaging the piston drive pin, the piston extending until the distal end of the piston reaches the distal surface of the cannula notch whereupon the piston distally pushes the drug up the inclined distal surface of the cannula notch to eject the drug laterally from the cannula notch.
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16. A biological agent delivery device comprising:
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a cannula having a distal end and a proximal end, the cannula having a longitudinally extending wall with a notch formed in said wall near the distal end for containing a biological agent, the cannula notch having a distal surface which extends distally outward and away from the proximal end of the cannula to form an inclined surface; and a displacement member disposed within the wall of the cannula for movement relative to the cannula to push the biological agent up the inclined distal surface of the cannula notch to deliver the biological agent laterally from the cannula notch. - View Dependent Claims (17, 18, 19)
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20. A product delivery device comprising:
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a cannula having a distal end and a proximal end, the cannula having a longitudinally extending wall with a notch formed in said wall near the distal end for containing a product, the cannula notch having a distal surface which extends distally outward and away from the proximal end of the cannula to form an inclined surface; and a displacement member disposed within the wall of the cannula for movement relative to the cannula to push the product up the inclined distal surface of the cannula notch to deliver the product laterally from the cannula notch. - View Dependent Claims (21, 22)
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Specification