Method and apparatus for treatment of atrial fibrillation

• US 5,562,708 A
• Filed: 04/21/1994
• Issued: 10/08/1996
• Est. Priority Date: 04/21/1994
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Combs, William J., Duffin, Edwin G., Rao, T. V.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US08/230,577
• Time in Patent Office: 901 Days
• Field of Search: 607/14, 607/148, 607/4, 607/5, 607/9, 607/129
• US Class Current: 607/4
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

A pacemaker system adapted to deliver pacing pulses in the presence of fibrillation. The pacing pulses are delivered via large surface area electrodes of the type normally used to accomplish defibrillation or cardioversion using high voltage pulses. An extended pulse train is delivered in order to gradually entrain greater portions of heart tissue, until a sufficient percentage of tissue is entrained to interrupt fibrillation. The invention is believed most applicable to treatment of atrial fibrillation.

Claims

1. An anti-fibrillation pacemaker, comprising:

means for detecting the presence of fibrillation in said chamber;

electrode means for simultaneously delivering pacing pulses to multiple sites dispersed over a chamber of a patient'"'"'s heart; and

pulse generator means responsive to the detection of fibrillation for providing a series of cardiac pacing pulses to said electrode means to simultaneously stimulate said multiple sites until fibrillation is terminated.

2. A pacemaker according to claim 1 wherein said pulse generator means comprises means for providing said pacing pulses unsynchronized to depolarizations of said chamber.

3. A pacemaker according to claim 1 wherein said electrode means comprises an epicardial electrode lead.

4. A pacemaker according to claim 1 or claim 2 wherein said pulse generator means comprises means for generating pulses of 0.05 joules or less for application to said chamber.

5. A pacemaker according to claim 1 or claim 2 wherein said pulse generator means comprises means for generating pulses of 5 millijoules or less for application to said chamber.

6. A method of treating fibrillation, comprising:

mounting an electrode on or in a chamber of a patient'"'"'s heart, such that said electrode is located adjacent multiple sites dispersed over said chamber;

detecting the presence of fibrillation;

response to the detection of fibrillation, providing a series of cardiac pacing pulses to said electrode to simultaneously stimulate said multiple sites, unsynchronized to depolarizations of said chamber, to terminate fibrillation.

7. A method according to claim 6 wherein said mounting step comprises mounting an epicardial electrode lead having a single electrode surface extending over said chamber.

8. A method according to claim 6 wherein said mounting step comprises mounting an epicardial electrode lead having multiple electrode surfaces dispersed over said chamber.

9. A method according to claim 6 or claim 7 or claim 8 wherein said step of providing pacing pulses comprises generating pulses of 0.05 joules or less for application to said chamber.

10. A method according to claim 6 or claim 7 or claim 8 wherein said step of providing pacing pulses comprises generating pulses of 5 millijoules or less for application to said chamber.

11. A method according to claim 6 or claim 7 or claim 8 wherein said mounting step comprises mounting said electrode to an atrium of said patient'"'"'s heart.

12. A method of treating fibrillation, comprising:

mounting an electrode lead having an electrode on or in a chamber of a patient'"'"'s heart, such that said electrode is located adjacent multiple sites dispersed over said chamber;

detecting the presence of fibrillation;

responsive to the detection of fibrillation, providing a series of cardiac pacing pulses to said electrode to simultaneously stimulate said multiple sites to terminate fibrillation.

13. A method according to claim 12 wherein said mounting step comprises mounting an epicardial electrode lead having a single electrode extending over said chamber.

14. A method according to claim 12 wherein said mounting step comprises mounting an epicardial electrode lead having multiple electrodes dispersed over said chamber.

15. A method according to claim 12 wherein said step of providing pacing pulses comprises generating pulses of 0.05 joules or less for application to said chamber.

16. A method according to claim 12 wherein said step of providing pacing pulses comprises generating pulses of 5 millijoules or less for application to said chamber.

17. A method according to claim 12 wherein said mounting step comprises mounting said electrode to an atrium of said patient'"'"'s heart.