Infusion device for soft tissue
First Claim
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1. An infusion device for infusion of a therapeutic substance into soft tissue, said device comprising:
- a receptacle for said therapeutic substance, said receptacle having a therapeutic substance emitting membrane, said membrane having an internal and an external surface, said internal surface being in contact with said therapeutic substance and having a plurality of pits spaced apart between 50 and 2,000 microns, said pits being between 50 and 2,000 microns across; and
a polymeric open-celled foam between 10 microns and 2,000 microns in thickness bonded to a substantial portion of said external surface of said membrane, said pits extending at least partially into said foam and at most 100 microns beyond said foam.
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Abstract
An implant is provided with an open-celled silicone elastomer foam outer layer. The implant may be formed by compressively deforming beads mixed with liquid elastomer in a mold containing a preformed support structure. The elastomer is cured and the beads dissolved out. Infusion and sensor catheters covered with the foam provide improved transport rates and faster response.
395 Citations
7 Claims
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1. An infusion device for infusion of a therapeutic substance into soft tissue, said device comprising:
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a receptacle for said therapeutic substance, said receptacle having a therapeutic substance emitting membrane, said membrane having an internal and an external surface, said internal surface being in contact with said therapeutic substance and having a plurality of pits spaced apart between 50 and 2,000 microns, said pits being between 50 and 2,000 microns across; and a polymeric open-celled foam between 10 microns and 2,000 microns in thickness bonded to a substantial portion of said external surface of said membrane, said pits extending at least partially into said foam and at most 100 microns beyond said foam. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification