17-formyl-5,6-trans-vitamin D compounds
First Claim
Patent Images
1. A compound having the formula:
- ##STR12## where Y1 is hydrogen or a hydroxy-protecting group, and R1 represents hydrogen, hydroxy or protected hydroxy.
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Accused Products
Abstract
The invention is drawn to 17-formyl vitamin D compounds having the following formula ##STR1## The compounds are intermediates in the production of 5,6-trans-(E)-20(22)-Dehydrovitamin D compounds which are useful for the treatment of diseases where bone formation is desired, such as osteoporosis, and for the treatment of diseases characterized by abnormal cell differentiation or cell proliferation, such as psoriasis.
12 Citations
1 Claim
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1. A compound having the formula:
- ##STR12## where Y1 is hydrogen or a hydroxy-protecting group, and R1 represents hydrogen, hydroxy or protected hydroxy.
Specification
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Current AssigneeWisconsin Alumni Research Foundation (University of Wisconsin System)
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Original AssigneeWisconsin Alumni Research Foundation (University of Wisconsin System)
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InventorsDeLuca, Hector F., Sicinski, Rafal R.
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Primary Examiner(s)Prior, Kimberly J.
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Application NumberUS08/147,663Time in Patent Office1,077 DaysField of Search552/653, 556/436, 556/449, 556/482, 568/445US Class Current552/653CPC Class CodesA61P 43/00 Drugs for specific purposes...C07C 401/00 Irradiation products of cho...C07J 71/0042 Nitrogen only
