Variable ratio blood-additive solution device and delivery system
First Claim
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1. A method for mixing blood and solution, for monitoring and for dispensing the mixture toward a site of perfusion comprising:
- (a) providing at least one source of blood and at least one source of solution;
(b) flowing said blood and flowing said solution together to form a flowing mixture having a predetermined ratio corresponding to the flow rates of said blood and said solution;
(c) delivering said flowing mixture of blood and solution at a predetermined rate of flow to a site of perfusion; and
(d) monitoring a ratio of blood to solution in said mixture by a method which comprises;
measuring the rate of flow within at least two of said flowing blood, said flowing solution, and said flowing mixture for calculation of the ratio of blood to solution.
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Abstract
A method and apparatus for delivering on command any ratio of blood to blood-additive solution of a blood/solution mixture during cardio vascular and cardiac perfusion procedures and more particularly to intermittently and/or continuously delivering on command any ratio of blood to cardioplegia solution of a blood/cardioplegia mixture during cardiac surgery.
53 Citations
18 Claims
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1. A method for mixing blood and solution, for monitoring and for dispensing the mixture toward a site of perfusion comprising:
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(a) providing at least one source of blood and at least one source of solution; (b) flowing said blood and flowing said solution together to form a flowing mixture having a predetermined ratio corresponding to the flow rates of said blood and said solution; (c) delivering said flowing mixture of blood and solution at a predetermined rate of flow to a site of perfusion; and (d) monitoring a ratio of blood to solution in said mixture by a method which comprises; measuring the rate of flow within at least two of said flowing blood, said flowing solution, and said flowing mixture for calculation of the ratio of blood to solution. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for delivering cardioplegia to a perfusion site comprising:
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(a) providing at least one source of blood and at least one source of solution; (b) providing a mixing site in communication with said at least one source of blood and said at least one source of solution; (c) selectively controlling the rate of flow of said at least one source of blood and said at least one source of solution to said mixing site to provide a blood and solution mixture having a predetermined ratio of blood to solution; (d) delivering said blood and solution mixture to a site of perfusion; (e) monitoring a ratio of blood to solution within said mixture by measuring a rate of flow within at least two of said blood flow, said solution flow, and said mixture flow; and
,(f) converting each flow rate measurement into an electronic signal corresponding to the measured rate of flow and which is readable by a computer. - View Dependent Claims (8, 9, 10, 11)
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12. A method for delivering at a consistent flow rate a blood-additive solution having a predetermined ratio selected within the range of all blood to all solution with respect to a given total volume for warm or cold cardioplegia treatment of a patient during open heart surgery comprising:
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(a) providing at least one source of blood and at least one source of solution; (b) providing a mixing site; (c) delivering blood from said at least one source of blood at a selectively variable controlled flow rate defining at least one first flow path to said mixing site; (d) delivering solution from said at least one source of solution at a selectively variable controlled flow rate defining at least one second flow path to said mixing site; (e) mixing said blood and said solution together at said mixing site to form a mixture having a predetermined ratio corresponding to the flow rates of said blood and said solution; (f) delivering said mixture of blood and solution at a predetermined rate of flow defining at least one third flow path to a site of perfusion; and (g) monitoring a ratio of blood to solution in said mixture by a method which comprises; (i) measuring the pressure of said mixture of blood and solution during delivery within said at least one third flow path to said site of perfusion; (ii) converting said pressure to an electronic signal corresponding to the pressure measured and which is readable by a computer; (iii) measuring the rate of flow within at least two of said at least one first flow path, said at least one second flow path, and said at least one third flow path; and (iv) converting each said flow measurement into an electronic signal corresponding to the measured rate of flow and which is readable by a computer for calculation of the ratio of blood to solution in said mixture. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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Specification