Apparatus for measuring oxygen saturation

• US 5,575,285 A
• Filed: 12/14/1994
• Issued: 11/19/1996
• Est. Priority Date: 12/21/1993
• Status: Expired due to Fees

• Current Assignee: KOWA Company Limited
• Original Assignee: KOWA Company Limited
• Inventors: Watanabe, Tsuyoshi, Ishikawa, Muneharu, Takanashi, Satohiko, Yamamoto, Tetsuya
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/355,516
• Time in Patent Office: 706 Days
• Field of Search: 128/633, 128/664, 356/41
• US Class Current: 600/323
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7253 characterised by using transforms
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

An apparatus for non-invasively measuring the oxygen saturation in the blood of a subject comprises light sources for irradiating a sample of blood in tissue with at least a first light beam and a second light beam having different wavelengths. A switching device drives the light sources and sequentially switches the irradiation of the sample of blood between the first and second laser beams. A photoelectric detector detects light transmitted through or reflected from the sample of blood and provides an electrical output signal indicative of the intensity of the detected light. A converter converts the electrical output signal of the photoelectric detecting device to a power spectrum, and a processor processes the power spectrum and calculates the oxygen saturation of the sample of blood. The blood oxygen saturation in the blood can be measured with high accuracy based on the detection of the light intensity transmitted through or reflected from the blood, regardless of the presence or absence of a pulsed blood flow. Additionally, by irradiating the subject by switching between laser beams of two wavelengths, the subject receives less irradiation than when two lasers are used at the same time. Thus even if the amount of irradiation at each wavelength is slightly increased, the accuracy measurement can be improved without adversely affecting the subject.

Claims

1. An apparatus for non-invasive measurement of oxygen saturation in a sample of blood in tissue of a subject, the apparatus comprising:

light means for irradiating a sample of blood in tissue of a subject with at least a first laser beam and a second laser beam;

switching means for driving the light means and sequentially switching the irradiation of the sample of blood between the first and second laser beams;

photoelectric detecting means for detecting light transmitted through or reflected from the sample of blood and providing an electrical output signal indicative of an intensity of the detected light; and

measuring means for measuring the oxygen saturation of the sample of blood from the electrical output signal of the detecting means, the measuring means comprising converter means for converting the electrical output signal of the detecting means to a power spectrum, and processing means for processing the power spectrum and calculating the oxygen saturation of the sample of blood.

2. An apparatus as claimed in claim 1;

wherein the first and second laser beams have different wavelengths.

3. An apparatus as claimed in claim 2;

wherein the wavelength of the first laser beam is in the region of 680 nm and the wavelength of the second laser beam is in the region of 805 nm.

4. An apparatus as claimed in claim 1;

wherein the converter means converts the electrical output signal to a power spectrum by fast Fourier transformation.

5. An apparatus as claimed in claim 1;

further comprising means disposed between the light means and the photoelectric detecting means for reflecting and focusing the first and second laser beams onto the sample of blood.

6. An apparatus as claimed in claim 5;

wherein the means for reflecting and focusing comprises a beam splitter and a prism for reflecting the laser beams, and at least one lens for focusing the laser beams onto the sample of blood.

7. An apparatus for non-invasive measurement of oxygen saturation in a sample of blood in tissue of a subject, the apparatus comprising:

light means for irradiating a sample of blood in tissue of a subject with at least a first light beam and a second light beam, the first and second light beams having different wavelengths;

switching means for driving the light means and sequentially switching the irradiation of the sample of blood between the first and second light beams;

photoelectric detecting means for detecting light transmitted through or reflected from the sample of blood and providing an electrical output signal indicative of an intensity of the detected light;

converter means for converting the electrical output signal of the detecting means to a power spectrum; and

processing means for processing the power spectrum and calculating the oxygen saturation of the sample of blood.

8. An apparatus as claimed in claim 7;

wherein the wavelength of the first light beam is in the region of 680 nm and the wavelength of the second light beam is in the region of 805 nm.

9. An apparatus as claimed in claim 7;

wherein the converter means converts the electrical output signal to a power spectrum by fast Fourier transformation.

10. An apparatus as claimed in claim 7;

further comprising means disposed between the light means and the photoelectric detecting means for reflecting and focusing the first and second light beams onto the sample of blood.

11. An apparatus as claimed in claim 10;

wherein the means for reflecting and focusing comprises a beam splitter and a prism for reflecting the laser beams, and at least one lens for focusing the laser beams onto the sample of blood.

12. A method of non-invasively measuring the oxygen saturation in a sample of blood in tissue of a subject, the method comprising the steps of:

sequentially directing at least a first laser beam and a second laser beam onto a sample of blood in tissue of a subject, the first and second laser beams having different wavelengths;

detecting light transmitted or reflected from the sample of blood and providing an electrical output signal indicative of an intensity of the detected light; and

measuring the oxygen saturation of the sample of blood from the electrical output signal by converting the electrical output signal indicative of the intensity of the detected light to a power spectrum, processing the power spectrum, and calculating the oxygen saturation of the sample of blood from the processed power spectrum.

13. A method as claimed in claim 12;

wherein the electrical output signal is converted to a power spectrum by fast Fourier transformation.

14. A method as claimed in claim 12;

wherein the light transmitted or reflected from the sample of blood is detected by a photoelectric detector.

15. A method of non-invasively measuring the oxygen saturation in the blood of a subject, the method comprising the steps of:

sequentially directing at least a first light beam and a second light beam onto a sample of blood in tissue of a subject, the first and second light beams having different wavelengths;

photodetecting light transmitted or reflected from the sample of blood and providing an electrical output signal indicative of an intensity of the detected light; and

converting the electrical output signal indicative of the intensity of the detected light to a power spectrum, processing the power spectrum, and calculating the oxygen saturation of the sample of blood from the processed power spectrum.

16. A method as claimed in claim 15;

wherein the electrical output signal is converted to a power spectrum by fast Fourier transformation.