Oxygen producing bandage and method

• US 5,578,022 A
• Filed: 04/12/1995
• Issued: 11/26/1996
• Est. Priority Date: 04/12/1995
• Status: Expired due to Term

• Current Assignee: Neogenix, Llc
• Original Assignee: Daniel A. Scherson, Melvyn I. Burk
• Inventors: Scherson, Daniel A., Burk, Melvyn I.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US08/421,679
• Time in Patent Office: 594 Days
• Field of Search: 604/303, 604/20, 604/304, 604/23, 604/305, 604/48, 604/306, 604/289, 604/307, 604/290, 604/308, 607/50, 128/640
• US Class Current: 604/304
• CPC Class Codes: A61F 13/05 specially adapted for use with sub-pressure or over-pressure therapy, wound drainage or wound irrigation, e.g. for use with negative-pressure wound therapy [NPWT]
• CPC Class Codes: A61F 13/069 Decubitus ulcer bandages
• CPC Class Codes: A61F 2013/00157 for burns or skin transplants A61F2013/00187 takes precedence; not adhering to the wound A61F2013/00217
• CPC Class Codes: A61F 2013/0017 possibility of applying fluid
• CPC Class Codes: A61F 2013/00365 use
• CPC Class Codes: A61F 2013/00519 for treating burn
• CPC Class Codes: A61F 2013/00902 containing means
• CPC Class Codes: A61F 2013/0097 oxygen content

Abstract

A portable, self-contained device is described for the topical application of oxygen to promote the healing of skin wounds. The device is comprised of a wound dressing that incorporates an electrochemical, chemical, or thermal means of generating high purity oxygen. The device can regulate the supply of oxygen to an area above the wound at various concentrations, pressures and dosages. The device is driven by a built in or accessory power source. Ambient air is brought into contact with a gas permeable cathode. Oxygen present in the air is reduced at the cathode to negative ions (i.e. peroxide, superoxide or hydroxyl ions) and/or their unprotonated and protonated neutral species. One or more of these species diffuse through an electrolyte and are then oxidized at a gas permeable anode to produce a high concentration of oxygen directly above the wound. Oxygen can also be depleted from that same area by reversing the polarity of the power source allowing the supply of oxygen to the wound to be modulated, thereby controlling the rate of healing.

Claims

1. A device for supplying oxygen for topical treatment of skin wounds, comprising:

a wound dressing patch adapted for receipt over a skin wound treatable with oxygen; and

an oxygen generating device incorporated within the wound dressing patch for supplying oxygen to the skin wound.

2. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein a supply of oxygen may be modulated between 0% and 100% oxygen concentration.

3. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein the oxygen generating device generates oxygen electrochemically and includes:

a cathode for reducing oxygen in a feed gas to negative ions and/or neutral species;

an electrolyte for diffusing the negative ions and/or neutral species therethrough; and

an anode communicating with the electrolyte for oxidizing the negative ions and/or neutral species to produce a high concentration oxygen for supply to the skin wound.

4. A device for supplying of oxygen for topical treatment of skin wounds, according to claim 3, wherein the production of oxygen occurs according to a one, two or four electron process.

5. A device for suppling oxygen for topical treatment of skin wounds, according to claim 3, wherein the negative ions are peroxide ions in their various unprotonated and protonated forms.

6. A device for supplying oxygen for topical treatment of skin wounds, according to claim 3, wherein the negative ions are superoxide ions including their protonated form.

7. A device for supplying oxygen for topical treatment of skin wounds, according to claim 3, wherein the negative ions are hydroxyl ions and the overall process involves electrolysis of water.

8. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein the oxygen generating device generates oxygen according to an electrochemical process and includes a power source which applies a potential difference between a cathode and anode to concentrate oxygen from ambient air.

9. A device for supplying oxygen for topical treatment of skin wounds, according to claim 8, wherein the power source is incorporated into the patch.

10. A device for supplying oxygen for topical treatment of skin wounds, according to claim 9, wherein the power source is a bipolar battery incorporated into the device.

11. A device for supplying oxygen for topical treatment of skin wounds, according to claim 9, wherein a zinc/air battery incorporated into the device supplies power to conduct the concentration of oxygen from air according to a one, two or four electron process.

12. A device for supplying oxygen for topical treatment of skin wounds, according to claim 8, wherein the power source is external to the patch.

13. A device for supplying oxygen for topical treatment of skin wounds, according to claim 8, wherein the power source is selected from the group consisting of capacitors, supercapacitors, photovoltaic cells, batteries, and alternating current power.

14. A device for supplying oxygen for topical treatment of skin wounds, according to claim 8, wherein polarity on the power source is reversible to modulate a concentration of oxygen.

15. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein the oxygen generating device generates oxygen according to a thermally induced reaction.

16. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein the oxygen generating device generates oxygen according to a chemically induced reaction.

17. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein the oxygen generating device supplies oxygen to the skin wound at various pressures ranging from below atmospheric pressure to above atmospheric pressure.

18. A device for supplying oxygen for topical treatment of skin wounds, according to claim 17, wherein the pressures range from about 0.5 atmospheres to about 5 atmospheres.

19. A device for supplying oxygen for topical treatment of skin wounds, according to claim 17, wherein the pressures range from about 0.75 atmospheres to about 2.5 atmospheres.

20. A device for supplying oxygen for topical treatment of skin wounds, according to claim 17, wherein the pressures range from about 0.95 to about 1.1 atmospheres.

21. A device for supplying oxygen for topical treatment of skin wounds, according to claim 1, wherein the device is comprised of a plurality of layers.

22. A device for supplying oxygen for topical treatment of skin wounds, according to claim 21, wherein one of said plurality of layers comprises a battery.

23. A device for supplying oxygen for topical treatment of skin wounds, according to claim 21, wherein one of said plurality of layers comprises a medicinal.

24. A device for supplying oxygen for topical treatment of skin wounds, according to claim 21, wherein one of said plurality of layers comprises a sensor.

25. A device for supplying oxygen for topical treatment of skin wounds, according to claim 24, wherein the sensor includes control circuitry to promote optimal healing.

26. A device for supplying oxygen for topical treatment of skin wounds, according to claim 21, wherein one of said plurality of layers comprises an oxygen concentrator.

27. A method for treating skin wounds using an electrochemical cell, comprising the steps of:

bringing ambient air into contact with a gas permeable cathode;

reducing oxygen present in the air to negatively charged ions or neutral species at the cathode;

diffusing the negatively charged ions or neutral species through an electrolyte to a gas permeable anode;

oxidizing the negatively charged ions or neutral species to oxygen at the anode; and

modulating a supply of oxygen to a skin wound.

28. A method for treating skin wounds using an electrochemical cell, according to claim 27, comprising the additional step of:

fully occluding a bandage incorporating the cathode, electrolyte and anode to skin surrounding a skin wound.

29. A method for treating skin wounds using an electrochemical cells according to claim 27, comprising the additional steps of:

killing anaerobic bacteria;

inhibiting toxic formation by anaerobic bacteria; and

controlling or preventing aerobic bacterial infection through concentrated oxygen.

30. A method for treating skin wounds using an electrochemical cell, according to claim 27, wherein the supply of oxygen to a skin wound modulates between 0% and 100% oxygen concentration at various pressures ranging from below atmospheric pressure to above atmospheric pressure.

31. A method for treating skin wounds using an electrochemical cell, according to claim 30, comprising the additional step of:

supplying oxygen to a skin wound at pressures ranging between about 0.5 atmospheres and about 5 atmospheres.

32. A method for treating skin wounds using an electrochemical cell, according to claim 27, including the additional step of providing a power source to an electrochemical cell such that the method employs a one, two or four electron process.

33. A method for treating skin wounds, comprising the steps of:

placing an oxygen generating wound dressing patch over a skin wound, a power source supplying energy to the patch;

bringing air into contact with a cathode incorporated in the wound dressing patch;

reducing oxygen present in the air to negative ions or neutral species at the cathode;

diffusing the negative ions and/or neutral species through an electrolyte to an anode, the electrolyte and anode incorporated in the wound dressing patch;

converting the negative ions and/or neutral species to dioxygen at the anode; and

passing the dioxygen out the anode to the skin wound.

34. A method for treating skin wounds, according to claim 33, wherein the dioxygen is passed from the anode to the skin wound.

35. A method for treating skin wounds, according to claim 33, wherein the dioxygen is directed away from the skin wound upon a reversal of polarity in the power source.

36. A method for treating skin wounds, according to claim 33, wherein the negative ions may be selected from peroxide ions, super oxide ions or hydroxyl ions.

37. A method for treating skin wounds, comprising the steps of:

placing an oxygen generating wound dressing patch over a skin wound;

generating oxygen within the wound dressing-patch; and

supplying oxygen to the skin wound.

38. A method for treating skin wounds, according to claim 37, including the additional step of:

generating oxygen according to an electrochemical process.

39. A method for treating skin wounds, according to claim 37, including the additional step of:

generating oxygen according to a thermally induced oxygen release reaction.

40. A method for treating skin wounds, according to claim 37, including the additional step of:

generating oxygen according to a chemically induced reaction.

41. A method for treating skin wounds, according to claim 37, including the additional step of:

supplying oxygen to the skin wound at pressures ranging from about 0.5 atmospheres to about 5 atmospheres.

42. A method for treating skin wounds, according to claim 37, comprising the additional step of:

controlling a rate of wound healing by increasing or decreasing the oxygen tension in tissues that stimulate healing.

43. A device for supplying oxygen to skin, comprising:

a dressing adapted for receipt over an area of skin; and

an oxygen generating device incorporated within the dressing for supplying a topical treatment of oxygen to the skin.

44. A device for supplying oxygen to skin, according to claim 43, wherein the oxygen generating device generates oxygen electrochemically.

45. A device for supplying oxygen to a skin wound, comprising:

a dressing adapted for receipt over a skin wound treatable with oxygen; and

an oxygen generating device incorporated within the dressing for supplying oxygen to the skin wound according to an electrochemical process, the oxygen generating device including a power source which applies a potential difference between a cathode and an anode to concentrate oxygen from ambient air.

46. A device for supplying oxygen to a skin wound, comprising:

a dressing adapted for receipt over a skin wound treatable with oxygen; and

an oxygen generating device incorporated within the dressing for supplying oxygen to the skin wound electrochemically including;

a cathode for reducing oxygen in a feed gas to negative ions and/or neutral species;

an electrolyte for diffusing the negative ions and/or neutral species therethrough; and

an anode communicating with the electrolyte for oxidizing the negative ions and/or neutral species to produce a high concentration of oxygen for supply to the skin wound.