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Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity

  • US 5,578,315 A
  • Filed: 12/01/1993
  • Issued: 11/26/1996
  • Est. Priority Date: 12/01/1993
  • Status: Expired due to Fees
First Claim
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1. A mucosal adhesive dosage unit adapted to use for treatment of oral cavity infection selected from a) the forms consisting of a dosage unit wherein mucoadhesive polymer layer having intermixed pharmaceuticals is adhered to a protective backing layer, and b) a tablet comprising a mucosal adhesive polymer mixture having intermixed pharmaceuticals;

  • said mucosal adhesive dosage unit adhering to the oral mucosal tissue for at least about 12 hours,said mucosal adhesive dosage unit having a therapeutic dosage amount of one or more antimicrobial agents and one or more anti-inflammatory agents,said dosage unit releasing the antimicrobial agent and anti-inflammatory agent at a substantially constant rate for at least 12 hours to treat infection in the oral mucosa.

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