Method of delivering liquid to a patient via a disposable pumping cassette having a flow control & pressure monitoring member

• US 5,586,868 A
• Filed: 06/25/1995
• Issued: 12/24/1996
• Est. Priority Date: 05/13/1994
• Status: Expired due to Term

• Current Assignee: Hospira Incorporated (Pfizer Inc.)
• Original Assignee: Abbott Laboratories Incorporated
• Inventors: Lawless, Michael W., Kaul, Ashok, Soberon, Peter A., Hermann, Robert A., Hoerner, Gregory G., Minick, Steven E., Kreinick, Stephen J.
• Primary Examiner(s): Thorpe, Timothy
• Assistant Examiner(s): McAndrews, Jr., Roland G.
• Application Number:
  US08/494,986
• Time in Patent Office: 548 Days
• Field of Search: 417/53, 417/63, 417/478, 417/479, 417/480, 604/153, 128/DIG. 12
• US Class Current: 417/53
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 39/281 Automatic tube cut-off devices, e.g. squeezing tube on detection of air
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: F04B 43/0054 particularities of the flexible members
• CPC Class Codes: F04B 43/02 having plate-like flexible members, e.g. diaphragms F04B43/14 takes precedence
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

A disposable pumping cassette having an integral auxiliary flow control and pressure monitoring member is used for delivering a medicinal fluid to a patient. The pumping cassette includes an elastomeric member mounted in a rigid body having an inlet and an outlet. An inlet valve and an outlet valve on the cassette are opened, and the flow control is positioned to allow the medicinal fluid to flow freely through the cassette, priming it before the outlet is connected to the patient. The cassette is then coupled to an associated pump driver, closing the flow control to disable free fluid flow through the cassette, and the outlet of the cassette is coupled in fluid communication with the patient'"'"'s body. The medicinal fluid is drawn into a pumping chamber formed in the rigid body as a plunger of the associated pump driver is drawn up from the elastomeric membrane at a recess formed in the rigid body. The plunger is then advanced downwardly, forcing the elastomeric membrane into the pumping chamber to deliver the medicinal fluid to the patient. The pressure of the fluid delivered to the patient is monitored through contact of the auxiliary flow control member with the elastomeric membrane over an outlet channel of the cassette.

Claims

1. A method of delivering a fluid to a patient, comprising the steps of:

a. providing a disposable pumping cassette having a pumping chamber, an inlet valve, and an outlet valve;

b. priming said cassette with the fluid to be administered to the patient;

c. coupling the cassette to an associated pump driver;

d. advancing a plunger of the associated pump driver to force the fluid through the cassette, past the outlet valve, and thus, to deliver the fluid to the patient;

e. providing an auxiliary flow control member on the cassette to control free fluid flow through the cassette and to monitor fluid pressure when the cassette is installed in the pump; and

f. monitoring the pressure of the fluid discharged from said outlet valve.

2. The method of claim 1, further comprising the step of monitoring the pressure of the fluid at the inlet port of the casette.

3. The method of claim 1, wherein the auxiliary flow control member is selectively operable in one of an open position in which the fluid flows freely through the cassette, and a closed position in which the free flow of the fluid is interrupted, further comprising the step of enabling the user to select one of the open and closed positions of the auxiliary flow control member position.

4. The method of claim 3, further comprising the step of providing a cassette engagement surface on the associated pump driver that automatically changes the auxiliary flow control member to the closed position when the cassette is coupled to the associated pump driver, if the auxiliary flow control member was previously in the open position.

5. The method of claim 4, wherein the auxiliary flow control member comprises a switch that s rocked between the open position and the closed position.

6. The method of claim 1, wherein the cassette further comprises an elastomeric member that is positioned inside said cassette and that overlies the inlet valve, outlet valve and pumping chamber, said auxiliary flow control member acting upon said elastomeric member to control fluid flow through the cassette and to monitor fluid pressure.

7. The method of claim 6, wherein the auxiliary flow control member overlies an outlet pressure port formed in the cassette and disposed downstream of the outlet valve.

8. The method of claim 6, wherein the cassette further comprises a pump port that provides access through a surface of the cassette to a portion of the elastomeric member overlying the pump chamber inside said cassette, said pump port being disposed so that when the cassette is coupled to the associated pump driver, the plunger reciprocates against the elastomeric member through said port to force fluid from the pumping chamber through the outlet valve.

9. The method of claim 8, wherein the inlet valve and the outlet valve comprise flapper check valves formed on the elastomeric membrane, said inlet and outlet valves only allowing the fluid to flow through the cassette in one direction, said one direction being into the inlet valve, through the pumping chamber, and out the outlet valve.

10. The method of claim 4, further comprising the step of using the auxiliary flow control member to displace the elastomeric membrane sufficiently to force the flapper check valve comprising the outlet valve closed to inhibit a free flow of the fluid through the cassette.

11. The method of claim 10, wherein the step of monitoring the pressure of the fluid discharged from the outlet valve includes the step of providing a pressure sensor in the associated pump driver, said pressure sensor including a member that contacts the elastomeric membrane to transmit force to the pressure sensor that is indicative of the pressure of the fluid discharged from the outlet valve.

12. A method for controlling a flow of a fluid through a disposable cassette, said cassette having a housing in which a fluid path is defined adjacent a surface of an elastomeric membrane, said cassette further including a fluid path along which are disposed an inlet valve that is integral with the elastomeric membrane, a pumping chamber, and an outlet valve that is integral with the elastomeric membrane, comprising the steps of:

a. providing a flow control member on the cassette, said flow control member being selectively moved to a free flow position to apply a force against the elastomeric member, thereby displacing the elastomeric membrane sufficiently to open the outlet valve so that the fluid flows freely through the cassette along the fluid path;

b. enabling the flow control member to be moved to a pressure monitoring position in which the flow control member is in contact with the elastomeric membrane, but does not cause the outlet valve to open; and

c. monitoring a pressure of the fluid discharged from the cassette in response to a force exerted by the fluid against the elastomeric membrane, said force being transmitted through the elastomeric membrane to the flow control member, which is adapted to convey the force to a pressure sensor disposed outside the cassette.