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Oligonucleotides having phosphorothioate linkages of high chiral purity

  • US 5,587,361 A
  • Filed: 06/06/1995
  • Issued: 12/24/1996
  • Est. Priority Date: 10/15/1991
  • Status: Expired due to Term
First Claim
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1. A phosphorothioate oligonucleotide complementary to a sequence of targeted RNA or DNA wherein at least 75% of the nucleoside units of said oligonucleotide are joined together by Sp phosphorothioate 3'"'"' to 5'"'"' intersugar linkages.

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