Method for generating gas to deliver liquid from a container

• US 5,588,556 A
• Filed: 06/05/1995
• Issued: 12/31/1996
• Est. Priority Date: 08/06/1993
• Status: Expired due to Term

• Current Assignee: Alisanae Group Limited
• Original Assignee: River Medical, Inc. (Envision Healthcare Corporation)
• Inventors: Sancoff, Gregory E., Doyle, Mark C., Field, Frederic P.
• Primary Examiner(s): Shaver, Kevin P.
• Application Number:
  US08/461,871
• Time in Patent Office: 575 Days
• Field of Search: 222/1, 222/386, 222/386.5, 222/394, 222/396, 222/397, 222/399, 222/389, 604/145, 239/322, 239/323, 169/33, 169/85, 424/44, 422/305
• US Class Current: 222/1
• CPC Class Codes: A61M 2005/1404 Keep vein-open rate [KVO], i.e. low flow rate
• CPC Class Codes: A61M 2005/14204 with gas-producing electrochemical cell
• CPC Class Codes: A61M 5/1409 in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems needle sets A61M5/162
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure
• CPC Class Codes: A61M 5/1483 using flexible bags externally pressurised by fluid pressure
• CPC Class Codes: A61M 5/155 pressurised by gas introduced into the reservoir
• CPC Class Codes: B01J 7/02 by wet methods
• CPC Class Codes: B65D 83/625 the propellant being generated by a chemical or electrochemical reaction for pressure gas in portable fire extinguishers A62C13/02

Abstract

The present invention relates to chemical reactants, compositions, methods to manufacture reactants, and apparatus for the generation of a gas pressure to drive a fluid from an infusion pump at controlled flow rates.

Claims

1. In an apparatus for the delivery of a liquid from a container, of the type wherein the apparatus includes a first and a second chemical, the first and second chemical being reactive to generate carbon dioxide gas, with the first chemical being disposed in solid form and the second chemical being disposed as a liquid, the improvement comprising:

the first chemical being admixed with a rate limiting amount of a rate controlling moiety and formed into a solid mass.

2. A method to generate carbon dioxide gas for the controlled delivery of a liquid from a container, comprising:

providing a first and a second chemical, said first and second chemicals being reactive to generate carbon dioxide gas upon contact therebetween at a substantially constant rate, said chemicals being initially separated from one another;

allowing said first and second chemicals to come into contact and react to generate the gas; and

communicating said gas to means operative to drive the liquid from the container,

wherein, the gas generating reaction is continued for a sufficient length of time to deliver the liquid from the container and the liquid is driven from the container at a substantially constant flow rate.

3. A method to generate carbon dioxide gas for the controlled delivery of a liquid from a container, comprising:

providing an alkali metal carbonate formed into a tablet and a liquid chemical that is reactive with the carbonate to generate carbon dioxide gas, said chemicals being initially separated from one another, and wherein said tablet is at least partially coated with a barrier that is at least partially insoluble in the liquid chemical;

allowing said first and second chemicals to come into contact and react to generate the gas at a substantially constant rate; and

communicating said gas to means operative to drive the liquid from the container at a substantially constant flow rate.

4. A method to generate carbon dioxide gas for the controlled delivery of a liquid from a container, comprising:

providing a first and a second chemical, said first and second chemicals being reactive to generate a gas upon contact therebetween, said chemicals being initially separated from one another;

allowing said first and second chemicals to come into contact and react to generate a gas such that upon attainment of the predetermined pressure within the first container, the container is maintained at said predetermined pressure through pressure maintenance means; and

communicating said gas to means operative to drive a liquid from said container at a substantially constant flow rate.

5. The method of claim 4, wherein said pressure maintenance means is a pressure relief valve in fluid communication with said container.

6. The method of claim 4, further comprising controlling the reaction rate between said first and second chemicals by admixing au least one of said chemicals with a rate limiting amount of a rate controlling moiety.

7. The method of claim 4, wherein said second chemical is a liquid and said first chemical is a tablet at least partially coated with a barrier that is at least partially insoluble in the liquid chemical, and said method further comprises controlling the reaction rate between said first and second chemicals by the amount of barrier coated onto said tablet.