Side flow bubble trap apparatus and method

• US 5,591,251 A
• Filed: 12/22/1994
• Issued: 01/07/1997
• Est. Priority Date: 11/29/1993
• Status: Expired due to Term

• Current Assignee: Gambro Renal Products, Inc. (Baxter International Inc.)
• Original Assignee: COBE Laboratories Incorporated (Terumo Corporation)
• Inventors: Brugger, James M.
• Primary Examiner(s): BHAT, NINA NMN
• Application Number:
  US08/362,262
• Time in Patent Office: 747 Days
• Field of Search: 422/44, 422/47, 604/4, 604/408, 604/122, 128/DIG. 3, 96/176, 96/179, 96/180, 210/436, 210/645, 95/242, 95/268
• US Class Current: 95/242
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 2205/7545 for solid matter, e.g. microaggregates

Abstract

An apparatus for trapping bubbles in blood flowing in a circuit, such as an extracorporeal circuit, includes a housing which defines a substantially vertical chamber having an upper subchamber and a lower subchamber. Blood flowing in a substantially downward direction is introduced into the upper subchamber chamber through a delivery port in a direction substantially transverse to a longitudinal axis of the upper subchamber. A substantially frustoconical deflector is positioned in the chamber opposite and spaced apart from the delivery port. The deflector deflects at least a portion of the blood into the upper subchamber above the deflector. Thereafter, the blood is removed from the chamber out an exit port of the chamber. The deflection and redirection of blood within the chamber provide an opportunity for gases in the blood to separate from the blood in the chamber and also helps prevent stagnation of blood in the chamber which might lead to clotting of the blood. A method of removing bubbles from blood flowing in a circuit involves introducing blood into a substantially vertical chamber at an angle substantially transverse to a longitudinal vertical axis of the chamber. At least a portion of the blood is deflected upward in the chamber by contact with a frustoconical deflector to allow gases to separate from the blood. The blood is then removed from the chamber.

Claims

1. A method of removing bubbles from blood flowing through a bubble trap apparatus in an extracorporeal blood treatment circuit, said apparatus including a housing having an upper housing end and a lower housing end, the housing defining a substantially vertical chamber extending substantially along a vertical longitudinal axis between said upper and lower housing ends, said chamber having a substantially cylindrical upper subchamber and a lower subchamber, said upper subchamber being offset from said lower subchamber and having upper and lower level indicator marks formed thereon, said method comprising the steps of:

introducing blood into the upper subchamber substantially transversely to the longitudinal axis of the chamber at a position intermediate between the upper and lower housing ends;

deflecting at least a portion of the blood introduced into the chamber with a frustoconical deflector above the position where the blood is introduced into the chamber to form a pool of blood in the chamber in the upper subchamber in a portion of the upper subchamber having a diameter wider than the diameter of the chamber adjacent the frustoconical deflector;

allowing bubbles in the blood to separate from the blood in the pool;

collecting the separated bubbles;

removing the blood from the chamber after the bubbles have been separated therefrom; and

maintaining an upper blood surface within the chamber between the upper and lower level indicator marks.

2. An apparatus for trapping bubbles in blood flowing in a circuit, said apparatus comprising:

a housing having an upper housing end and a lower housing end, said housing defining a substantially vertical, cylindrical and elongated interior chamber, said housing having a substantially vertical longitudinal axis;

an inlet tube formed in the housing, having an inlet tube diameter and extending into the chamber substantially transversely to the longitudinal axis of the chamber and at a position intermediate between the upper and lower housing ends, said inlet tube opening into the chamber at a delivery port through which blood is introduced into the chamber, said delivery port having an delivery port diameter;

a substantially frustoconical deflector formed in the housing and having a deflector tip, said deflector projecting into the chamber at a position intermediate between the upper and lower housing ends at the level of the delivery port and defining a narrowed channel of the chamber having a channel diameter narrower than a diameter of the chamber above the deflector and narrower than a diameter of the chamber below the deflector, said deflector positioned to deflect blood introduced through the inlet tube into the chamber above the deflector; and

an exit port formed in the housing through which blood is removed from the chamber.

3. The apparatus of claim 2 wherein the blood has an upper blood surface and the apparatus further comprises:

an upper subchamber of the chamber defined at its lower extreme by the channel and its upper extreme by the upper housing end, for mixing the deflected blood and collecting bubbles which have separated from the blood, said upper subchamber having a first longitudinal axis; and

a lower subchamber of the chamber defined at its upper extreme by the channel and at its lower extreme by the lower housing end, through which blood flows before removal out the exit port, said lower subchamber having a second longitudinal axis.

4. The apparatus of claim 3 further comprising:

a collar formed in the housing and surrounding the exit port; and

a filter having a rim, said filter positioned in the lower subchamber with the filter rim abutting the collar, to filter blood in the lower subchamber before removal of the blood out the exit port.

5. The apparatus of claim 4 further comprising:

a first aperture formed in the housing for removing bubbles from the chamber; and

a second aperture formed in the housing for adding fluid and materials to the blood in the chamber.

6. The apparatus of claim 3 further comprising:

an upper blood level indicator mark formed on the housing of the upper subchamber and a lower blood level indicator mark formed on the housing of the upper subchamber at a level intermediate the upper blood level indicator mark and the deflector edge, to provide guidelines between which to maintain the upper blood surface.

7. The apparatus of claim 3 wherein the inlet tube diameter is substantially the same length as the delivery port diameter.

8. The apparatus of claim 3 wherein the channel diameter is greater than the lower subchamber diameter.

9. The apparatus of claim 3 wherein the channel diameter is greater than the diameter of the lower subchamber and the inlet tube diameter is substantially the same length as the delivery port diameter.

10. The apparatus of claim 3 wherein the first longitudinal axis is parallel to and offset from the second longitudinal axis.

11. The apparatus of claim 2 wherein:

the blood flowing in the circuit has a range of flow rates of 50 ml/min to 700 ml/min; and

the product of the square of the delivery port diameter multiplied by the channel port diameter is between 185 mm³ and 450 mm³ inclusive.

12. A blow-molded apparatus for trapping bubbles in blood flowing in a circuit, said apparatus comprising:

a housing having an upper housing end and a lower housing end and defining a substantially vertical elongated chamber having a substantially cylindrical upper subchamber and a lower subchamber, said upper subchamber extending along a first longitudinal axis between the upper and lower housing ends and said lower subchamber extending along a second longitudinal axis between the upper and lower housing ends, said first longitudinal axis being parallel to and offset from said second longitudinal axis;

an inlet tube formed integrally with the housing and extending into the upper subchamber of the chamber at a delivery port located at and above a point intermediate between the upper and lower housing ends in a direction substantially transverse to the first longitudinal axis of the upper subchamber for introducing blood into the chamber at a position intermediate between the upper and lower housing ends in a flow direction substantially transverse to the first longitudinal axis, said inlet tube having an inlet tube diameter and said delivery port having a delivery port diameter;

a substantially frustoconical deflector positioned in the chamber adjacent to and spaced apart from the position at which the inlet tube introduces blood into the chamber, the deflector deflecting at least a portion of the blood into the chamber above the deflector, said deflector defining a neck of the housing above which is located the upper subchamber and below which is located the lower subchamber, said chamber having a channel diameter at the level of the neck, wherein said channel diameter is narrower than a diameter of the upper subchamber and narrower than a diameter of said lower subchamber; and

an exit port formed in the housing to allow blood to exit the chamber.

13. The apparatus of claim 12 wherein the inlet tube diameter is substantially the same as the delivery port diameter.

14. The apparatus of claim 13 wherein the channel diameter is greater than the diameter of the lower subchamber.

15. The apparatus of claim 14 further comprising:

a collar formed in the housing and surrounding the exit port; and

a filter having a rim, said filter positioned in the lower subchamber with the filter rim abutting the collar, to filter blood in the lower subchamber before removal of the blood out the exit port.

16. The apparatus of claim 14 further comprising:

a first aperture formed in the upper end of the housing for removing bubbles from the chamber; and

a second aperture formed in the housing at the upper housing end for adding fluid and materials to the blood in the chamber.

17. The apparatus of claim 12 wherein:

the blood flowing in the circuit has a range of flow rates of 50 ml/min to 700 ml/min; and

the product of the square of the delivery port diameter multiplied by the channel port diameter is between 185 mm³ and 450 mm³ inclusive.