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Smooth muscle chemical pacemaker

  • US 5,591,445 A
  • Filed: 10/10/1995
  • Issued: 01/07/1997
  • Est. Priority Date: 12/09/1992
  • Status: Expired due to Fees
First Claim
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1. A porous biocompatible matrix comprising an interspersed neuroactive agent forming a shaped solid element, wherein the neuroactive agent has a therapeutic effect on a disorder associated with smooth muscle function in an organ peripheral to the central nervous system and wherein the concentration of the neuroactive agent is about 1 to 30% by weight of the element, so that localized drug delivery to those in need thereof is provided through a thin film of fluid which forms when the matrix is contacted with an organ surface in vivo.

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