Apparatus and method for non-invasively detecting urinary tract infection using ultrasound

• US 5,592,941 A
• Filed: 10/20/1995
• Issued: 01/14/1997
• Est. Priority Date: 10/20/1995
• Status: Expired due to Term

• Current Assignee: Verathon Incorporated (Roper Technologies, Inc.)
• Original Assignee: Diagnostic Ultrasound Corporation (Roper Technologies, Inc.)
• Inventors: McMorrow, Gerald J.
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US08/546,068
• Time in Patent Office: 452 Days
• Field of Search: 128/660.02, 128/660.07, 128/661.02, 128/661.1, 128/662.02, 128/916, 73/610, 73/861.25
• US Class Current: 600/443
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: Y10S 128/916 Ultrasound 3-D imaging

Abstract

An ultrasound signal is transmitted into the center of the bladder. The received backscatter information is gated so that the data which remains is from a sample volume within the bladder and does not include information from the front or back walls and surrounding tissues of the bladder. The backscatter information is then compared with a preestablished threshold value. If the received backscatter is above a threshold value, it is indicative of a possible urinary tract infection, and an alarm is transmitted to the user.

Claims

1. An apparatus for detecting urinary tract infection, comprising:

ultrasound means for transmitting an ultrasound signal into a portion of the bladder;

means for receiving a return signal from the bladder;

means for gating the received signal so that only backscatter values from urine in a sample volume in the bladder remain; and

means for comparing said sample volume backscatter values against a pre-established threshold value, wherein a backscatter value above the threshold is indicative of the presence of elements in the urine which in turn indicate a urinary tract infection.

2. The apparatus of claim 1, including means for securing the ultrasound means to the person of a user.

3. The apparatus of claim 1, including means for determining an approximate centerline of the bladder and for transmitting the ultrasound signal along said centerline.

4. The apparatus of claim 1, wherein the gate signal permits passage of the return signal for a time duration in the range of 5-20 μ

seconds.

5. The apparatus of claim 1, wherein the gate signal begins to permit passage of the return signal at a selected time in the range of 30-50 μ

seconds following initial receipt of the return signal.

6. The apparatus of claim 1, including means for detecting the gated received signal with a synchronous quadrature detector.

7. The apparatus of claim 1, including means for providing an alarm to a user of the apparatus upon the threshold value being exceeded.

8. The apparatus of claim 1, including means for establishing the threshold value in accordance with backscatter values received from the user when there is no infection, wherein the threshold establishing means includes means for accumulating backscatter values over a selected period of time, establishing a mean value for said backscatter values and adding a multiple of a standard deviation value to the mean value.

9. An apparatus of claim 8, wherein the standard deviation is the maximum difference between the threshold establishing backscatter values and the mean value over the selected period of time and the multiple is approximately 2.5.

10. A method for detecting urinary tract infection, comprising:

transmitting an ultrasound signal into a portion of a bladder of a person;

receiving a return signal from the bladder;

gating the received signal so that only backscatter values from urine in a sample volume in the bladder remain; and

comparing the sample volume backscatter values against a pre-established threshold value, wherein a backscatter value above the threshold is indicative of the presence of elements in the urine which in turn indicate a urinary tract infection.

11. The method of claim 10, wherein the transmitted signal is transmitted along a centerline of the bladder and wherein the sample volume is established about said centerline between front and back walls of the bladder.

12. The method of claim 10, including the step of providing an alarm to a user of the apparatus upon the threshold value being exceeded.

13. The method of claim 10, including the step of establishing the threshold value in accordance with backscatter values received from the user when there is no infection, wherein the step of establishing includes the step of accumulating backscatter values over a selected period of time, establishing a mean value for said backscatter values and adding a multiple of a standard deviation value to the mean value.

14. A method of claim 13, wherein the standard deviation value is the maximum difference between the threshold establishing backscatter values and the mean value over the selected period of time and the multiple is approximately 2.5.