Stent capable of attachment within a body lumen

• US 5,593,434 A
• Filed: 06/07/1995
• Issued: 01/14/1997
• Est. Priority Date: 01/31/1992
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Inventors: Williams, Michael S.
• Primary Examiner(s): BRITTINGHAM, DEBRA
• Application Number:
  US08/473,003
• Time in Patent Office: 587 Days
• Field of Search: 623/1, 623/11, 623/12, 604/8, 606/194, 606/195, 600/36
• US Class Current: 128/898
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/92 Stents in the form of a rolled-up sheet expanding after insertion into the vessel , e.g. with a spiral shape in cross-section
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0019 operated at only one temperature whilst inside or touching the human body, e.g. constrained in a non-operative shape during surgery, another temperature only occurring before the operation
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2310/00017 Iron- or Fe-based alloys, e.g. stainless steel
• CPC Class Codes: A61F 2310/00023 Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00131 Tantalum or Ta-based alloys
• CPC Class Codes: A61F 2310/00149 Platinum or Pt-based alloys
• CPC Class Codes: A61F 2310/00155 Gold or Au-based alloys
• CPC Class Codes: A61L 29/02 Inorganic materials
• CPC Class Codes: A61L 29/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence
• CPC Class Codes: Y10S 623/903 Blood vessel

Abstract

An expandable, balloon catheter delivered intravascular stent, especially adapted for cardiovascular applications, having a plurality of protrusions on its outer surface for engaging the artery walls in which it is disposed. The protrusions are formed from the body of the stent in a unitary, one-piece manner. Apertures are formed in the stent body from the space vacated in the body by the material forming the protrusions. When the stent is expanded by the balloon catheter, the protrusions engage both the apertures and the artery walls, to lock the stent into the expanded diameter. In this way axial displacement and radial collapse of the stent is avoided. The protrusions are arranged in a plurality of shapes, sizes and patterns. The stent may be made of a bioabsorbable material and/or a therapeutic drug delivery material.

Claims

1. A method of securing an intravascular stent in a patient'"'"'s vasculature, comprising:

placing an intravascular stent over a balloon catheter, said stent having a length and circumference, a plurality of protrusions projecting from about the length and circumference of said stent, and a plurality of apertures about the length and circumference of said stent;

positioning said intravascular stent in a patient'"'"'s vasculature with said balloon catheter;

expanding said balloon catheter to expand said stent from a reduced diameter to an enlarged diameter form; and

securing said stent in said patient'"'"'s vasculature when said stent is in said enlarged diameter form, said securement occurring through said protrusions engaging said apertures as well as said protrusions engaging said patient'"'"'s vasculature.

2. The method of claim 1, wherein the step of positioning the intravascular stent in the patient'"'"'s vasculature includes the further step of:

percutaneously introducing the stent and balloon catheter into the patient'"'"'s vasculature.

3. The method of claim 2, wherein the step of percutaneously introducing the catheter into the patient'"'"'s vasculature includes the step of:

following the catheter along a previously positioned guidewire in the patient'"'"'s vasculature.

4. The method of claim 2, including the further steps of:

deflating the balloon catheter; and

withdrawing the balloon catheter from the patient'"'"'s vasculature, whereby the intravascular stent remains secured in the patient'"'"'s vasculature.

5. The method of claim 1, including the further step of:

impregnating the intravascular stent with a therapeutic agent to provide localized drug delivery to the patient'"'"'s vasculature.

6. A method of securing a stent within a body lumen, comprising:

placing a stent over an expandable catheter, said stent having a length and circumference, a plurality of protrusions about said length and circumference, and a plurality of apertures about said length and circumference;

introducing the stent and expandable catheter into a body lumen;

positioning said stent at a desired location in the body lumen with said expandable catheter;

expanding said expandable catheter to expand said stent from a reduced diameter to an enlarged diameter form; and

securing said stent in said enlarged diameter form at the desired location in said body lumen, said securement occurring through said protrusions securing said stent in its enlarged diameter form, said protrusions engaging against walls of said body lumen.

7. The method of claim 6, including the further steps of:

deflating the expandable catheter; and

withdrawing the catheter from the body lumen, whereby the stent is left in the desired location in the body lumen.

8. The method of claim 6, including the further step of:

impregnating the stent with a therapeutic agent to provide localized drug delivery to the body lumen.

9. The method of claim 6, including the further step of:

impregnating the stent with a radiopaque material.

10. The method of claim 6, wherein the step of positioning the stent at the desired location includes the further step of:

tracking the location of the stent with a fluoroscope.

11. A method of securing a stent within a body lumen, comprising:

placing a stent over an expandable catheter, said stent having a length and circumference, a plurality of protrusions projecting along said length and circumference, and a plurality of apertures about said length and circumference, said apertures corresponding to the shape of the protrusions;

introducing the stent and expandable catheter into a body lumen;

positioning said stent at a desired location in the body lumen with said expandable catheter;

expanding said expandable catheter to expand said stent from a reduced diameter to an enlarged diameter form;

locking said stent in said .enlarged diameter form, said locking occurring through one or more of the protrusions engaging one or more of the apertures; and

securing said stent at the desired location in said body lumen, said securement occurring through said protrusions engaging against walls of said body lumen.

12. The method of claim 11, including the further steps of:

cutting the protrusions from a generally planar sheet of biocompatible material, the protrusions unitary with and secured to the planar sheet; and

curling the sheet into a cylinder to form said stent.

13. The method of claim 12, wherein the step of cutting the protrusions includes forming apertures in the sheet, said apertures formed in said sheet as a result of the protrusions being cut from the sheet.

14. The method of claim 13, wherein the step of cutting the protrusions includes cutting the protrusions in a substantially "V" shape.

15. The method of claim 12, wherein the step of cutting the protrusions includes dispersing the protrusions on the sheet in a random pattern.

16. The method of claim 12, wherein the step of cutting the protrusions includes spacing the protrusions from one another in a substantially uniform manner to form rows of protrusions.

17. The method of claim 12, wherein the sheet has at least two ends, the method including the further step of:

beveling one or more ends of the sheet.