Tissue implant systems and methods for sustaining viable high cell densities within a host
First Claim
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1. A method of implanting cells comprising the steps ofproviding a wall comprising a porous boundary, wherein the wall defines a chamber for holding cells for implantation and the porous boundary has a given area (A);
- placing within the chamber a given number of cells (N) such that the quantity A/N is less than about 200 μ
m2 /cell; and
embedding the chamber within host tissue.
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Abstract
A method for implanting cells is disclosed which employs a chamber having a wall forming porous boundary between the host and implanted cells. According to the method, a given number of cells (N) is placed within the porous boundary of a given area (A) such that the quantity A/N is less than about 200 μm2 /cell. The porous boundary has a pore size, an ultimate strength, and a metabolic transit value that assures the survival of the cells during the critical ischemic period and afterward.
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6 Claims
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1. A method of implanting cells comprising the steps of
providing a wall comprising a porous boundary, wherein the wall defines a chamber for holding cells for implantation and the porous boundary has a given area (A); -
placing within the chamber a given number of cells (N) such that the quantity A/N is less than about 200 μ
m2 /cell; andembedding the chamber within host tissue. - View Dependent Claims (2, 3, 4, 5, 6)
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Specification