System for analyzing medical images having a particular color and intensity look-up table

• US 5,598,185 A
• Filed: 06/10/1994
• Issued: 01/28/1997
• Est. Priority Date: 06/10/1994
• Status: Expired due to Fees

• Current Assignee: Integrated Image Solutions
• Original Assignee: Integrated Image Solutions
• Inventors: Holmgren, Bengt G.
• Primary Examiner(s): Weinhardt, Robert A.
• Assistant Examiner(s): Thomas, Joseph
• Application Number:
  US08/258,059
• Time in Patent Office: 963 Days
• Field of Search: 364/413.22, 364/413.13, 364/413.14, 382/6, 382/41, 382/54-56, 382/162, 382/164, 382/128, 382/165, 382/132, 348/25, 348/26, 348/27, 348/28, 348/29, 348/30, 395/126, 395/129, 395/131, 395/132, 128/630, 345/147, 345/150, 345/153, 345/199
• US Class Current: 345/593
• CPC Class Codes: G06T 2207/10016 Video; Image sequence
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 30/20 for handling medical images, e.g. DICOM, HL7 or PACS

Abstract

A procedure and device for analyzing the gray scale of mammograms. Mammogram images are digitized and subject to image enhancement by manipulating the gray scale. Each pixel of the digitized mammogram is grouped as to a gray scale interval and those pixels lying in the same gray scale interval are assigned a common display value. The display values are displayed for each pixel location on both a color and monochrome monitor producing a unique pattern giving a finer detailed image of density changes in breast parenchyma. Interpretation of these patterns indicate suspicious areas where immediate magnification of the suspect area can produce a better image of a mass for application of known malignant tumor characteristics.

Claims

1. An apparatus for analyzing a mammogram to identify carcinoma-induced stress in tissue comprising:

a camera for creating a scanned video image from said mammogram;

a video signal digitizing means for creating a digitized image from said scanned video image comprising an array of pixels, each pixel defining a gray scale level for a point on said mammogram representing a tissue density recorded on said mammogram;

a computer including a video memory for storing said array of pixels, said computer being programmed to;

divide the array of pixels into discrete separate groups of pixels forming contiguous ranges of gray scales, each group including pixels having a gray scale value within a range unique to said group;

assigning a single pixel value to each pixel of each group said single pixel value selected so that adjacent groups comprise non-contiguous groups of a single pixel value;

addressing a look-up with each assigned pixel value, to produce a plurality of pixel colors having a saturation and intensity level defined by each assigned pixel value whereby each color includes a range of intensity levels, said intensity level increasing from a black level to a maximum level for increasing assigned pixel values whereby further increases in an assigned pixel value produces another color which increases in intensity level for increasing assigned pixel values; and

a display for displaying an image comprising said pixel colors, wherein pixels lying within each of said groups have the same display value, said image having discrete boundaries defined by non-contiguous pixel values representing a tissue density gradient produced by carcinoma-induced stress.

2. The apparatus according to claim 1 wherein said Look Up Table defines 64 color intensity levels for 256 assigned gray scale values.

3. The apparatus according to claim 1 further comprising means for varying the gray scale of said stored digitized image pixels.

4. A method for detecting stress induced in human tissue during the early stages of a malignant condition comprising:

forming a digital image of said tissue comprising a frame of pixels having a gray scale value representing a tissue density;

translating each pixel gray scale into one of a limited number of discrete gray scale values, so that pixels having a gray scale value which lies within a small gray scale interval have the same gray scale values, and adjacent intervals have non-contiguous gray scale values; and

,

displaying each of said discrete gray scale values at each pixel location, as a distinct color from a look-up table which translates each translated pixel gray scale value into one of a plurality of distinct colors, each color including a range of intensity values, said look up table defining an intensity level for each display color based on a translated pixel gray scale value, said intensity level increasing from a minimum intensity level to a maximum intensity level with increasing translated pixel gray scale values until a boundary is reached with another color, whereby areas of substantially constant tissue density are represented as contours having the same display value, and tissue areas of high stress produce several adjacent bands of different displayed values of a distinctive shape.

5. The method according to claim 4, wherein said boundary between colors is defined by a transition from said maximum intensity level to a black level.

6. The method for detecting stress induced in human tissue during the early stages of a malignant condition of claim 4 wherein said step of forming a digital image comprises:

illuminating a mammogram with a light box;

scanning an image produced by said mammogram to produce a scanned video image; and

digitizing said scanned video image.