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Printing molecular library arrays using deprotection agents solely in the vapor phase

  • US 5,599,695 A
  • Filed: 02/27/1995
  • Issued: 02/04/1997
  • Est. Priority Date: 02/27/1995
  • Status: Expired due to Term
First Claim
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1. A method of forming polymers having different monomer sequences on a substrate, said method comprising:

  • providing a substrate comprising a linker molecule layer thereon, said linker molecule layer comprising a linker molecule and a protective group;

    applying a barrier layer overlying said linker molecule layer, said applying step forming selected exposed regions of said linker molecule layer;

    exposing said selected exposed regions of said linker molecule layer to a deprotecting agent solely in a vapor phase, to solely remove the protective group; and

    coupling selected monomers to form selected polymers on the substrate.

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