Non-aqueous emiollient iodophor formulations

• US 5,607,699 A
• Filed: 05/12/1995
• Issued: 03/04/1997
• Est. Priority Date: 05/12/1995
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Khan, Mohammad A., Hoang, Minh Q.
• Primary Examiner(s): Weddington, Kevin E.
• Application Number:
  US08/440,288
• Time in Patent Office: 662 Days
• Field of Search: 424/405, 424/667, 424/669, 424/671, 424/672, 514/458
• US Class Current: 424/672
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 59/12 Iodine, e.g. iodophors; Compounds thereof
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 2800/31 Anhydrous
• CPC Class Codes: A61K 31/355 Tocopherols, e.g. vitamin E
• CPC Class Codes: A61K 33/18 Iodine; Compounds thereof
• CPC Class Codes: A61K 8/02 characterised by special physical form
• CPC Class Codes: A61K 8/20 Halogens; Compounds thereof
• CPC Class Codes: A61K 8/31 Hydrocarbons
• CPC Class Codes: A61K 8/39 Derivatives containing from 2 to 10 oxyalkylene groups
• CPC Class Codes: A61K 8/463 containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
• CPC Class Codes: A61K 8/86 Polyethers
• CPC Class Codes: A61K 8/90 Block copolymers A61K8/89 takes precedence
• CPC Class Codes: A61K 8/922 of vegetable origin
• CPC Class Codes: A61K 8/9794 Liliopsida [monocotyledons]
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: Y02A 50/30 Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Non-aqueous emollient iodophor formulations for use as a skin washing agents, comprising non-ionic surfactants, coconut oil, mineral oil, iodine, sodium iodide and an organic base solvent. The non-aqueous formulations substantially do not irritate the skin and will provide antimicrobial effectiveness to the skin.

Claims

1. An emollient, non-aqueous iodophor formulation comprising:

(a) a non-ionic pluronic surfactant containing 50-70% ethylene oxide in amount from about 10 to 20 weight percent of the total composition;

(b) a nonylphenoxypolyethyleneoxy ethanol in an amount from about 10 to about 20 weight percent of the total composition;

(c) a coconut oil diethanolamine condensate in an amount from about 0.5 to about 2.0 weight percent of the total composition;

(d) a polyoxyethylene 4 lauryl ether in an amount from about 5 to about 15 weight percent of the total composition;

(e) an ethoxylated lanolin in an amount from about 1 to about 5 weight percent of the total composition;

(f) an alkylaryl sulfonate in an amount from about 1 to about 5 weight percent of the total composition;

(g) a mineral oil in an amount from about 1 to about 5 weight percent of the total composition;

(h) iodine crystals in an amount from about 0.5 to about 2.5 weight percent of the total composition;

(i) sodium iodide in an amount from about 0.5 to about 2.0 weight percent of the total composition;

(j) aloe vera in an amount from about 0.1 to about 2.0 weight percent of the total composition; and

(k) propylene glycol in an amount from about 18.0 to about 70.0 weight percent of the total composition.

2. The formulation of claim 1 further comprising:

(1) a fragrance in an amount from about 0.1 to about 1.0 weight percent of the total composition.

3. The formulation of claim 2 further comprising:

(m) vitamin E in an amount from about 0.1 to about 1.0 weight percent of the total composition.