Methods for reducing blood loss
First Claim
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1. A method of reducing perioperative blood loss in a patient undergoing surgery comprising administering to said patient an effective amount of factor XIII in a biologically compatible vehicle, wherein said factor XIII is substantially free of other blood coagulation factors and wherein said factor XIII is administered to said patient prior to or during said surgery, whereby perioperative blood loss by said patient is reduced.
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Abstract
Blood loss in a patient undergoing surgery, particularly thoracic or abdominal surgery, is reduced by administration of factor XIII. The factor XIII may be administered in combination with aprotinin.
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12 Claims
- 1. A method of reducing perioperative blood loss in a patient undergoing surgery comprising administering to said patient an effective amount of factor XIII in a biologically compatible vehicle, wherein said factor XIII is substantially free of other blood coagulation factors and wherein said factor XIII is administered to said patient prior to or during said surgery, whereby perioperative blood loss by said patient is reduced.
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12. A method of reducing perioperative blood loss in a patient undergoing surgery comprising administering to said patient a composition consisting essentially of factor XIII in a biologically compatible vehicle, wherein said factor XIII is administered to said patient prior to or during said surgery, whereby perioperative blood loss by said patient is reduced.
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