Non-invasive method and apparatus for monitoring intracranial pressure and pressure volume index in humans
First Claim
1. A method for non-invasive measurement of intracranial pressure and pressure volume index in a patient, comprising the steps of:
- (a) calibrating a measuring device by introducing known changes in intracranial pressure and reading the corresponding pressure changes with the measuring device;
(b) inducing known changes in the volume of the cerebrospinal fluid while measuring the corresponding changes in intracranial pressure with the calibrated measuring device;
(c) obtaining two sets of corresponding values for change in volume and change in intracranial pressure; and
(d) obtaining values for the pressure volume index and the intracranial pressure for the patient based on the values for change in volume and change in intracranial pressure.
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Abstract
Non-invasive measuring devices responsive to changes in a patient'"'"'s intracranial pressure (ICP) can be accurately calibrated for monitoring purposes by providing known changes in ICP by non-invasive methods, such as placing the patient on a tilting bed and calculating a change in ICP from the tilt angle and the length of the patient'"'"'s cerebrospinal column, or by placing a pressurized skull cap on the patient and measuring the inflation pressure. Absolute values for the patient'"'"'s pressure-volume index (PVI) and the steady state ICP can then be determined by inducing two known changes in the volume of cerebrospinal fluid while recording the corresponding changes in ICP by means of the calibrated measuring device. The two pairs of data for pressure change and volume change are entered into an equation developed from an equation describing the relationship between ICP and cerebrospinal fluid volume. PVI and steady state ICP are then determined by solving the equation. Methods for inducing known changes in cerebrospinal fluid volume are described.
128 Citations
9 Claims
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1. A method for non-invasive measurement of intracranial pressure and pressure volume index in a patient, comprising the steps of:
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(a) calibrating a measuring device by introducing known changes in intracranial pressure and reading the corresponding pressure changes with the measuring device; (b) inducing known changes in the volume of the cerebrospinal fluid while measuring the corresponding changes in intracranial pressure with the calibrated measuring device; (c) obtaining two sets of corresponding values for change in volume and change in intracranial pressure; and (d) obtaining values for the pressure volume index and the intracranial pressure for the patient based on the values for change in volume and change in intracranial pressure. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method for calibrating a device for monitoring changes in intracranial pressure in a patient comprising the steps of:
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(a) applying a measuring device to the patient to provide output signals in response to changes in intracranial pressure; (b) inducing a known change in intracranial pressure by placing the patient on a tiltable bed and calculating said known change in intracranial pressure from the length of the patient'"'"'s cerebrospinal system and the tilt angle of the bed; and (c) recording an output signal from said measuring device corresponding to said known change in intracranial pressure.
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9. A method for calibrating a device for monitoring changes in intracranial pressure in a patient comprising the steps of:
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(a) applying a measuring device to the patient to provide output signals in response to changes in intracranial pressure; (b) inducing a known change in intracranial pressure by placing an inflatable cap on the patient'"'"'s skull and inflating said cap to a known pressure; and (c) recording an output signal from said measuring device corresponding to said known change in intracranial pressure.
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Specification