Pressure-driven attachable topical fluid delivery system

• US 5,618,269 A
• Filed: 05/04/1995
• Issued: 04/08/1997
• Est. Priority Date: 05/04/1995
• Status: Expired due to Fees

• Current Assignee: Sarcos Incorporated (Rtx Corporation)
• Original Assignee: Sarcos Incorporated (Rtx Corporation)
• Inventors: Jacobsen, Stephen C., Davis, Clark C., Backman, Kent
• Primary Examiner(s): Rimell, Sam
• Assistant Examiner(s): Racunas, Robert V.
• Application Number:
  US08/435,092
• Time in Patent Office: 705 Days
• Field of Search: 604/4, 604/30, 604/31, 604/33, 604/65, 604/66, 604/67, 604/80, 604/81, 604/93, 604/118, 604/131, 604/132, 604/151, 604/152, 604/153, 222/243, 222/275, 222/409, 222/630, 222/206, 222/207, 222/209, 222/212, 222/213, 222/214, 222/215, 417/378, 417/391, 417/395
• US Class Current: 604/118
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 5/16809 by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142

Abstract

A fluid delivery device for delivering fluid from a fluid reservoir to a patient. The device includes an inlet channel in communication with a fluid reservoir and a dosing chamber, and an outlet channel disposed in communication with the dosing chamber. A reciprocating dosing actuator is moveable in a reciprocating motion between first and second positions for alternately (i) transporting a dose of fluid conveyed by the inlet channel into the intermediate dosing chamber, and (ii) ejecting the dose from the dosing chamber through the outlet channel to the patient, respectively.

Claims

1. A fluid delivery device for delivering fluid to a patient comprising:

a reservoir for containing a supply of the fluid;

an inlet channel disposed in fluid communication with the reservoir;

an outlet channel disposed in series and in fluid communication with the inlet channel such that said inlet channel resides between the reservoir and the outlet channel;

pressure means disposed on the reservoir for exerting a continuous positive pressure within said reservoir;

a housing having interior walls including first and second interior side walls defining an intermediate dosing chamber, said first side wall having an inlet port formed therein and said second side wall having an outlet port and an intermediate port formed therein, the inlet and outlet channels being disposed in communication with the dosing chamber via the inlet port and the outlet port, respectively;

a resilient membrane sealably attached in an expanded configuration along a circumferential portion thereof to the interior walls of the housing to divide the dosing chamber into first and second sections, said membrane having a first side facing the inlet port to define the first section and an opposing second side facing the outlet port and the intermediate port to define the second section, such that elastic memory of the molecular structure of the membrane acts to contract the membrane toward the inlet port, said membrane being alternately expandable toward the outlet port to a diastolic position and contractible toward the inlet port to a systolic position;

guide channel means disposed in communication with the inlet channel, inlet port and intermediate port for channeling fluid between the inlet channel and the inlet port, and between the inlet port and the intermediate port;

dosing actuation means disposed on the guide channel means including a reciprocating portion being movable in a reciprocating motion between second and first positions for respectively (i) releasing fluid flow between the inlet channel and the inlet port while blocking fluid flow between the inlet port and the intermediate port to permit pressure exerted by the pressure means to force a dose of fluid from the reservoir into the first section of the dosing chamber and against the membrane to forcibly expand the membrane into a diastolic position, and (ii) releasing fluid flow between the inlet port and the intermediate port while blocking fluid flow between the inlet channel and the inlet port to thereby shield the membrane from pressure exerted by the pressure means and permit the elastic memory of the membrane to contractably move the membrane toward the inlet port to a systolic position to force the dose of fluid out of the first section of the dosing chamber back through the inlet port toward the intermediate port to thereby force a dose of fluid through the intermediate port into the second section of the dosing chamber, such that when said reciprocating portion of the actuation means is moved into the second position the dose of fluid which is forced into the first section of the dosing chamber and which forcibly expands the membrane toward the outlet port into a diastolic position thereby causes the membrane to eject a previous dose of fluid residing in the second section of the dosing chamber out of the outlet channel to the patient.

2. A fluid delivery device as defined in claim 1, wherein the membrane includes an outer perimeter edge and is continuously sealed to the interior walls of the housing along substantially the entire perimeter edge such that the first and second sections of the dosing chamber are divided by the membrane.

3. A fluid delivery device as defined in claim 1, wherein the expanded configuration of the membrane and the elastic memory of the molecular structure of the membrane co-act to contract the membrane toward the inlet port and against the first interior side wall of the housing to a systolic position when the reciprocating portion of the dosing actuation means is moved to the second position.

4. A fluid delivery device as defined in claim 1, wherein the guide channel means and the dosing actuation means collectively comprise:

first channel means disposed to fluidly connect the inlet channel with the inlet port, said first channel means having a diversion port formed therein at a point between the inlet channel and the inlet port;

second channel means disposed to fluidly connect the diversion port with the intermediate port;

first valve means disposed in the first channel means between the inlet channel and the diversion port for alternately blocking and releasing fluid flow within the first channel means when maneuvered into closed and opened positions, respectively;

second valve means disposed in the second channel means between the diversion port and the intermediate port for alternately blocking and releasing fluid flow within the second channel means when maneuvered into closed and opened positions, respectively; and

reciprocating actuation means movable into a first position for opening the first valve means and closing the second valve means, and into a second position for closing the first valve means and opening the second valve means, such that a distal section of the first channel means between the diversion port and the inlet port alternately channels fluid in first and second opposing directions in that movement of the reciprocating actuation means into the first position causes said distal section to channel fluid in a first direction toward the inlet port into the first section of the dosing chamber, and movement of the reciprocating actuation means into the second position causes said distal section to channel fluid in a second direction away from the inlet port and toward the diversion port and intermediate port into the second section of the dosing chamber.

5. A fluid delivery device as defined in claim 4, wherein the reciprocating actuation means further comprises:

support means;

first and second valve pins each including a proximal and a distal end, said first and second valve pins being slidably disposed in the support means and being respectively biased toward the first and second valve means and thereby tending to maintain said first and second valve means in closed positions, such that movement of the valve pins into the support means causes the distal ends of said pins to move into contact with their respective valve means to thereby force said valve means into closed positions;

first and second lever means respectively attached at first portions thereof to the support means and being respectively biased at second opposing portions thereof against proximal ends of the first and second valve pins in first switched positions for exerting pressure upon said valve pins to thereby force said first and second valve pins into contact with the first and second valve means;

rigid shaft means including a shaft body and first and second opposing ends, said shaft means being pivotally mounted to the support means at a pivot point thereof, said first opposing end having first and second opposing sides, said second opposing end including first and second rod members extending laterally outward in opposing directions from the shaft body;

first shape memory means secured at one end thereof to the support means and attached at an opposing end thereof to the first side of the first end of the shaft means;

second shape memory means secured at one end thereof to the support means and attached at an opposing end thereof to the second side of the first end of the shaft means;

means for alternately passing electrical current through the first and second shape memory means to thereby alternately cause the first shape memory means and the second shape memory means to contract in alternating tandem, wherein contraction of the first shape memory means causes the shaft means to pivot about its pivot point in one pivotal direction and wherein contraction of the second shape memory means causes the shaft means to pivot about its pivot point in a second pivotal direction, such that the contraction of the first and second shape memory means in alternating tandem causes the first and second rod members to forcibly push the second portions of the first and second lever means away from the support means into second switched positions to thereby mobilize the first and second valve means into open positions and then slide said rod members away from said first and second lever means to release said lever means back into their natural biased positions against the first and second valve pins in alternating tandem.

6. A fluid delivery device as defined in claim 1, wherein the intermediate dosing chamber comprises a lens-shaped concavo-convex chamber such that the first interior side wall comprises a convex wall and the second interior side wall comprises a concave wall, wherein said convex and concave walls are joined together at their perimeters to form an intermediate circumferential section of the dosing chamber, said resilient membrane being sealably attached in an expanded configuration along a circumferential portion thereof to said intermediate circumferential section of the dosing chamber.

7. A fluid delivery device as defined in claim 1 further comprising pressure varying means connected to the pressure means for selectively varying magnitude of the pressure exerted by the pressure means within the reservoir, to thereby vary the rate of transport of the fluid to and from the dosing chamber.

8. A fluid delivery device as defined in claim 4, wherein the reciprocating actuation means further comprises:

shaft means disposed between the first and second valve means, said shaft means including first and second opposing portions and being pivotally anchored at a pivot point thereof;

first and second shape memory means attached to opposite sides of the second opposing portion of the shaft means, said first shape memory means being operable to move the shaft means away from the first valve means and into contact with the second valve means to thereby close said first valve means and open said second valve means, said second shape memory means being operable to move the shaft means away from the second valve means and into contact with the first valve means to thereby close said second valve means and open said first valve means;

means for alternately passing electrical current through the first and second shape memory means to thereby alternately cause the first shape memory means and the second shape memory means to contract in alternating tandem.

9. A fluid delivery device as defined in claim 1, wherein the outlet means includes a distal end portion configured for attachment to an intravenous needle to thereby permit the fluid delivery device to deliver fluid into a vein of the patient.

10. A fluid delivery device as defined in claim 1 wherein said device is portable and miniaturized and configured for attachment to the patient to thereby enable the device to be carried by the patient.

11. A fluid delivery device as defined in claim 10 wherein said device is dimensioned and sized to be swallowable by the patient to thereby enable said device to deliver fluid within an intracorporeal region of the patient.

12. A fluid delivery device as defined in claim 10 further including attachment means for attaching the device to an exterior portion of the patient to thereby enable the device to deliver the fluid to the patient in a topical manner.

13. A fluid delivery device as defined in claim 1 further comprising control means including timing means, said control means being connected to the dosing actuation means for activating and deactivating said dosing actuation means responsive to a timing signal produced by the timing means.

14. A fluid delivery device as defined in claim 1 further comprising control means including sensing means responsive to physiological conditions of the patient, said control means being connected to the dosing actuation means for activating and deactivating said dosing actuation means responsive to an actuation signal produced by the sensing means.

15. A fluid delivery device as defined in claim 5 wherein the first and second valve means comprise resilient membrane material disposed in the first and second channel means, respectively, such that movement of a valve pin into the membrane material causes said membrane material to block fluid flow within the channel means.

16. A fluid delivery device as defined in claim 5, wherein at least one of the first and second opposing sides of the first opposing end of the shaft means includes a finger member formed thereon, and wherein the attachment of shape memory means to said at least one of the first and second opposing sides comprises said shape memory means being looped around said finger member.