Method and apparatus for determination of a criterion of activity of a rate modulation parameter sensor in an active implantable medical device

• US 5,622,428 A
• Filed: 12/27/1995
• Issued: 04/22/1997
• Est. Priority Date: 12/30/1994
• Status: Expired due to Term

• Current Assignee: Sorin CRM USA (MicroPort Scientific Corp.)
• Original Assignee: Ela Medical S.A. (LivaNova Plc)
• Inventors: Bonnet, Jean-Luc
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/578,967
• Time in Patent Office: 482 Days
• Field of Search: 607/17, 364/413.01
• US Class Current: 600/300
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: Y10S 128/92 Computer assisted medical diagnostics

Abstract

The process of determining a criterion of activity of a sensor used to measure a parameter of enslavement in an active implantable medical device. The process is characterized by the following steps:

a) acquisition of successive samples of the representative value of the parameter from a signal collected by the sensor,

b) calculation over a first interval of time of a first average value (AVE_-- SENSOR_-- SHORT_-- TERM) of the activity from the samples acquired by the sensor;

c) calculation over a second interval of time, greater than the first, of a second average value (AVE_-- SENSOR_-- 24H) of the activity of the sensor from acquired samples, and

d) determination of a criterion of activity of the sensor, by comparison of the first average value and the second average value, notably by giving to the criterion of activity a first value (Rest) defining a state of rest of the patient if the first average value (AVE_-- SENSOR_-- SHORT_-- TERM) is less than the second average value (AVE_-- SENSOR_-- 24H), and a second value (Non-Rest) defining a state of non-rest of the patient in the opposite case.

Claims

1. A process for determining a criterion of activity of a sensor for measuring a parameter serving to control at least one function in an active implantable medical device, comprising the steps of:

a) acquiring successive samples of a representative value of the parameter from a signal collected by the sensor;

b) calculating over a first interval of time a first average value (AVE_-- SENSOR_-- SHORT_-- TERM) of the activity of the sensor from the samples acquired during said first time interval;

c) calculating over a second interval of time, the second time interval being greater than the first, a second average value (AVE_-- SENSOR_-- 24H) of the activity of the sensor from the samples acquired during said second time interval; and

d) determining a criterion of activity of the sensor based on a comparison of the first average value and the second average value.

2. The process of claim 1, further comprising the step of defining at least one of the first and the second time intervals using an internal clock of the device.

3. The process of claim 1, further comprising the step of defining at least one of the first and second time intervals by counting a number of samples acquired by the sensor.

4. The process of claim 3, further comprising defining the first time interval by counting a number of samples selected from between 1 and 1024 samples.

5. The process of claim 1, further comprising providing the second time interval as a duration of approximately 24 hours.

6. The process of claim 1, further comprising providing the criterion of activity of the sensor as a binary criterion having a first state and a second state (Rest, Non-Rest).

7. The process of claim 6, wherein step d) further comprises setting the criterion of activity to a first value (Rest) defining a state of rest of the patient in response to the first average value (AVE_-- SENSOR_-- SHORT_-- TERM) being less than the second average value (AVE_-- SENSOR_-- 24H), and a second value (Non-Rest) defining a state of non-rest of the patient in response to the second average value being less than the first average value.

8. The process of claim 1, further comprising a step of determining a first value of minimal activity level and a second value of maximal activity level of the sensor as respective functions of the second average value (AVE_-- SENSOR_-- 24H) calculated at step c).

9. The process of claim 8, wherein determining the first value of minimal activity level of the sensor further comprises limiting an excursion of the first value to a range between an upper limit and a lower limit.

10. The process of claim 9, further comprising providing the lower limit by applying a predetermined coefficient (1-THRESH_-- MIN%) to the second average value.

11. The process of claim 10 wherein providing the lower limit further comprises providing an integer coefficient.

12. The process of claim 9, further comprising providing the upper limit by applying a predetermined coefficient (1+THRESH_-- MAX%) to the second average value.

13. The process of claim 12 wherein providing the upper limit further comprises providing a coefficient of approximately 1.5.

14. The process of claim 1, further comprising controlling a function of enslavement of the active implantable medical device by the criterion of activity of the sensor.

15. The process of claim 1, further comprising steps of:

i) providing a lower limit by applying a predetermined coefficient (1-THRESH_-- MIN%) to the second average value;

ii) providing an upper limit by applying a predetermined coefficient (1+THRESH_-- MAX%) to the second average value;

iii) determining a value of minimal activity level of the sensor (REST_-- VAL_-- SENSOR) for the aforementioned control function of the active implantable medical device as a function of the second average value (AVE_-- SENSOR_-- 24H) calculated as step c), and the upper limit and the lower limit; and

iv) limiting an excursion of the value to a range between the upper and lower limits.

16. The process of claim 15 further comprising controlling a function of enslavement of the active implantable medical device by the criterion of activity of the sensor, and providing a value of adjustment of the low point of the calibration of the function of enslavement of the active implantable medical device as the value of the minimal activity level of the sensor (REST_-- VAL_-- SENSOR).

17. Apparatus for determining a criterion of activity of a sensor for measuring a parameter serving to control at least one function in an active implantable medical device, comprising:

a sensor for measuring a device function control parameter;

means, responsive to the sensor, for acquiring successive samples of a representative value of the measured parameter;

first means for calculating a first average value of the activity of the sensor from the samples acquired during a first time interval;

second means for calculating a second average value of the activity of the sensor from the samples acquired during a second time interval, the second time interval being greater than the first; and

means for determining a criterion of activity of the sensor based on a comparison of the first average value and the second average value.

18. The apparatus of claim 17 further comprising an internal clock wherein at least one of the first and the second time intervals is based on the internal clock.

19. The apparatus of claim 17, further comprising a counter having a count corresponding to a number of acquired samples wherein at least one of the first and second time intervals is defined by the counter count reaching a preselected value.

20. The apparatus of claim 19 wherein the first time interval is defined by the counter count reaching a number of samples selected from between 1 and 1024 samples, and wherein the second time interval is a duration of approximately 24 hours.

21. The apparatus of claim 17, wherein the criterion of activity of the sensor is a binary criterion having a first state and a second state.

22. The apparatus of claim 17, wherein the determining means further comprises means for comparing the first average value and the second average value, and the criterion of activity is set to a first value defining a state of rest of the patient in response to the first average value being less than the second average, and a second value defining a state of non-rest of the patient in response to the first average value not being less than the second average value.

23. The apparatus of claim 22 wherein the aforementioned function controlled by the criterion of activity of the sensor is a function of enslavement of the active implantable medical device and the value of the minimal activity level of the sensor further comprises a value of the adjustment of the low point of the calibration of the function of enslavement of the active implantable medical device.

24. The apparatus of claim 17, further comprising means for determining a value of minimal activity level of the sensor for the aforementioned control function of the active implantable medical device as a function of the second average value, wherein the second average value is limited to a value in a range between an upper limit and a lower limit.

25. The apparatus of claim 24, wherein the lower limit is a function of a first predetermined coefficient applied to the second average value, and the upper limit is a function of a second predetermined coefficient applied to the second average value.

26. The apparatus of claim 25 wherein the first predetermined lower limit is an integer coefficient and the second predetermined coefficient is approximately 1.5.

27. The apparatus of claim 17 wherein the aforementioned function controlled by the criterion of activity of the sensor is a function of enslavement of the active implantable medical device.