Variable-pulse dynamic fluid flow controller

• US 5,624,409 A
• Filed: 06/10/1994
• Issued: 04/29/1997
• Est. Priority Date: 06/10/1994
• Status: Expired due to Term

• Current Assignee: FluidSense Corporation, Mack Ventures, Inc.
• Original Assignee: FluidSense Corporation
• Inventors: Seale, Joseph B.
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US08/257,872
• Time in Patent Office: 1,054 Days
• Field of Search: 604/65-67, 604/246-247, 604/153, 604/30-34, 604/49-53, 604/118, 604/151, 128/DIG. 13, 128/DIG. 12
• US Class Current: 604/246
• CPC Class Codes: A61M 5/16809 by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: G05D 7/0635 by action on throttling means G05D7/0688, G05D7/0694 take precedence

Abstract

A dynamic controller for quantitative rapid-pulse flow control over a wide dynamic range (1000-to-1) forms a fluid path from a pressurized source to a sink. The fluid path travels, typically in a disposable cassette, from the pressure source via a fast (one millisecond) on-off source control valve into a volume-displacement interface area, thence to a fast on-off load control valve and on to the sink. The load control valve may be replaced by a passive flow restrictor where less dynamic range is required. From the reusable controller side, fast actuators are energized to open the normally-closed valves. A volume sensor mates with the volume-displacement interface area. This sensor uses an incompressible transfer fluid, typically different than and isolated from the deliverable fluid by membranes, to transmit volume displacement change into a transducer area for conversion from volume to a measurable electrical signal, typically a frequency. A known pressure/volume curve for the volume sensor allows pressure monitoring during operation, yielding knowledge of fluid source and load conditions.

A flow control method relies on a combination of very short, variable valve-open pulses and design with comparatively large-diameter fluid passageways into the fluid capacitance of the volume sensor, to achieve flow limited more by inertia than viscosity. Distinct high-flow and low-flow control regimes are used. For high flow, bolus volume is maximized by pulsing for one-half the fluid oscillation period determined by the volume sensor fluid capacitance and the flow inertia of the fluid passageway, shutting off at flow reversal. For low flow, pulses typically below 10% of the high-flow pulse width yield small bolus volumes varying as the square of pulse width, providing control over a wide dynamic range of bolus sizes down to fractions of a microliter, permitting moderately high pulse frequencies even at very low average rates, achieving nearly continuous flow. Design with normally-closed, energize-to-open valves assures flow stop if power is lost. In this context, the large fluid passageways lead to a prescribed volume transfer at low valve-open duty cycle, conserving energy and making battery operation practical.

Claims

1. A system for controlling the flow of a fluid from a source to a sink comprising:

a. a source valve couplable to a fluid source containing a deliverable fluid, wherein said source valve is capable of regulating flow of said deliverable fluid from said source;

b. a fluid pathway connecting said source valve to a sink;

c. a volume displacement sensor couplable to said fluid pathway, wherein said sensor converts displacement into an electrical signal; and

d. controller means responsive to said electrical signal from said sensor, said controller means acting on said source valve so that said source valve delivers a controlled selectable bolus volume of said deliverable fluid to said sink.

2. The system as claimed in claim 1 wherein said source valve is positioned between said fluid source and said volume displacement sensor, said system further comprising a second valve coupled between said volume displacement sensor and said sink with said controller means acting on said second valve so as to aid in the delivery of said controlled selectable volume of said deliverable fluid to said sink.

3. The system as claimed in claim 1 wherein said controller means includes means for delivering said fluid to said sink at a controllable variable bolus frequency so as to provide a variable prescribed average volumetric flow rate of said fluid.

4. The system as claimed in claim 3 wherein said sink is a patient.

5. A system for controlling the flow of a deliverable fluid from a source to a sink, wherein source pressure exceeds sink pressure, comprising:

a. a disposable cassette coupled to said source, said disposable cassette comprising source opening/closing means in contact with a source valve, wherein said source valve is coupled to a deliverable fluid source of said source via a fluid pathway; and

b. a reusable controller section comprising;

i. a volume displacement sensor coupled to said fluid pathway, wherein said sensor converts displacement into an electrical signal; and

ii. controller means responsive to said electrical signal from said sensor, said controller means acting on said source valve so that said source valve delivers a controlled selectable bolus volume of said deliverable fluid to said sink.

6. The system as claimed in claim 5 further comprising a sink valve coupled between said volume displacement sensor and said sink with said controller means acting on said sink valve so that said sink valve aids in the delivery of said controlled selectable volume of said deliverable fluid to said sink, and wherein said disposable cassette includes sink opening/closing means in contact with said sink valve.

7. The system as claimed in claim 6 wherein said source opening/closing means includes a source valve actuator component and said sink opening/closing means includes a sink actuator component, wherein said actuator components open and close said source valve and said sink valve quickly.

8. The system as claimed in claim 5 with said volume displacement sensor comprising a sensor cavity having an incompressible volume transfer fluid contained therein, wherein said incompressible volume transfer fluid is volumetrically displaced by said deliverable fluid when said deliverable fluid moves from said source to said sink.

9. The system as claimed in claim 8 wherein said sensor cavity includes barrier means between said incompressible volume transfer fluid and said deliverable fluid.

10. The system as claimed in claim 9 wherein said barrier means comprises a reusable fluid-impermeable elastic material.

11. The system as claimed in claim 9 with said volume displacement sensor further comprising a volume displacement interface between said barrier means and said deliverable fluid, wherein said volume displacement interface prevents mixing of said incompressible volume transfer fluid and said deliverable fluid.

12. The system as claimed in claim 7 wherein said source actuator and said sink actuator are electrical solenoids.

13. The system as claimed in claim 7 wherein said source actuator and said sink actuator are voice-coil drivers.

14. The system as claimed in claim 7 wherein said source actuator and said sink actuator are piezoelectric transducers.

15. The system as claimed in claim 7 with said controller section further comprising means for determining said timing of the opening and closing of said source and sink valves, said determination means comprising:

a. means for converting said electrical signal into a linear measure of volume;

b. computation means responsive to said linear measure of volume and controlling said timing to achieve a prescribed average volumetric flow rate;

c. as part of said computation means, means for computing from said linear measure a measure of volume transfer from said source to said sink; and

d. as part of said computation means, means for adjusting timing of said source and sink valves, responsive to said measure of volume transfer, and responsive to said prescribed average volumetric flow rate, causing said measure of volume transfer to cumulatively approximate said prescribed average volumetric flow rate.

16. The system as claimed in claim 15 further including, as part of said means for adjusting said timing of said source and sink valves, means for setting valve-open timing periods to yield deliverable fluid flow for approximately half the natural period of oscillation of volume to and from said volume displacement sensor via the open one of said source and sink valves.

17. The system as claimed in claim 15 further including, as part of said means for adjusting said timing of said source and sink valves, means for setting valve-open timing periods to yield deliverable fluid flow for substantially less than half the natural period of oscillation of volume of deliverable fluid to and from said volume displacement sensor via the open one of said source and sink valves.

18. The system as claimed in claim 15 further including means for converting said electrical signal into a linear measure of pressure, and, as part of said computation means, means to determine pressures at said fluid source and said fluid sink.

19. A dynamic system for variably controlling average volumetric flow rate driven by a variable fluid pressure differential from a source to a sink by use of variable valve timing, volume displacement sensing, and flow restriction, including:

a. a fluid source and a fluid sink wherein source pressure exceeds sink pressure;

b. a source valve capable of opening and closing quickly under electronic control, wherein said source valve regulates the flow of deliverable fluid from said source;

c. a volume displacement sensor for receiving said deliverable fluid from said source via said source valve, wherein said volume displacement sensor includes means to convert volume displacement into a quantifiable electrical signal;

d. a flow restrictor between said sensor and said sink, said flow restrictor for regulating flow rate of said deliverable fluid from said sensor in relation to pressure in said sensor and in said sink; and

e. controller means responsive to said electrical signal, wherein said controller means controls the timing of said opening and closing quickly of said source valve to achieve controllable variable fluid bolus size and frequency into said sensor so as to provide a variable prescribed average volumetric flow rate of said deliverable fluid from said sensor via said flow restriction into said sink.

20. A system for controlling the flow of a fluid from a source to a sink comprising:

a. a fluid pathway for coupling said source to said sink;

b. a valve couplable to said fluid pathway, wherein said valve is capable of regulating flow of said deliverable fluid within said fluid pathway;

c. a volume displacement sensor couplable to said fluid pathway, wherein said sensor is capable of converting displacement of said fluid into an electrical signal; and

d. controller means responsive to said electrical signal from said sensor, said controller means capable of acting on said valve so that said valve delivers a controlled selectable bolus volume of said deliverable fluid to said sink.