×

Phenyl derivatives useful as tachykinin antagonists

  • US 5,624,947 A
  • Filed: 06/20/1995
  • Issued: 04/29/1997
  • Est. Priority Date: 12/21/1992
  • Status: Expired due to Fees
First Claim
Patent Images

1. A compound of formula (I), or a pharmaceutically acceptable salt or prodrug thereof:

  • ##STR13## wherein R1 is imidazoyl nitro, NRa Rb and NRa CORb, where Ra and Rb each independently represent H, C1-6 alkyl or phenyl optionally substituted by C1-6 alkyl, halo or trifluoromethyl;

    R2 represents H, C1-6 alkyl or C2-6 alkenyl;

    R3 represents C1-3 alkyl substituted by a phenyl group which may itself optionally be substituted by one or more of C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, halo, cyano, nitro, trifluoromethyl and trimethylsilyl;

    R4 represents H, C1-6 alkyl or C2-6 alkenyl;

    each R5 independently represents C1-6 alkyl, C1-6 alkoxy, halo or trifluoromethyl;

    Z represents O or S; and

    m represents 0, 1, 2 or 3.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×