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Polymeric-hydroxyapatite bone composite

  • US 5,626,861 A
  • Filed: 04/01/1994
  • Issued: 05/06/1997
  • Est. Priority Date: 04/01/1994
  • Status: Expired due to Fees
First Claim
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1. A method for making a porous composite for repair or replacement of hone comprising hydroxyapatite mixed with a biodegradable, biocompatible polymer, wherein the pores have a diameter in the range of between approximately 100 and 250 microns comprisingmixing hydroxyapatite particles having a particle size in the range of approximately 10 and 100 microns in diameter with a non-aqueous solution of a biodegradable, biocompatible polymer dissolved in a polymer solvent,suspending particles of an inert leachable material with the hydroxyapatite particles, wherein the particles of inert leachable material have a diameter between approximately 100 and 250 microns and are not soluble in the polymer solvent,removing the polymer solvent, andremoving the inert leachable material to yield a composite having pores with a diameter of at least 100 microns wherein the effective strength of the composite is a function of the hydroxyapatite:

  • polymer ratio.

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