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Multifunctional organic polymers

  • US 5,627,233 A
  • Filed: 06/06/1995
  • Issued: 05/06/1997
  • Est. Priority Date: 10/15/1990
  • Status: Expired due to Term
First Claim
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1. A method for making a biocompatible polymeric material the method comprisingforming a biocompatible copolymer which is selected from the group consisting of copolymers having the formulas (A)x(B)y;

  • (A)x(B)y(A)z;

    (B)x(A)y(B)z; and

    a brush copolymer (A)x-(B)y having bristles of poly(A);

    wherein (A)x, (A)y and (A)z are biocompatible synthetic polymers and mixtures of polymers that form a region which is polynonionic at a pH of between 6.5 and 8.5 and does not bind tissue; and

    wherein (B)y, (B)x, and (B)z are biocompatible, water-soluble synthetic polymers or mixture of polymers that form a region which is polycationic at a pH of between 6.5 and 8.5 and binds to tissue; and

    wherein x is an integer of greater than or equal to 5, y is an integer of greater than or equal to 3, and z is an integer of greater than or equal to 0;

    wherein the polymer has a molecular weight of at least 300 g/mole.

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