Implantable leads incorporating cardiac wall acceleration sensors and method of fabrication

• US 5,628,777 A
• Filed: 07/14/1993
• Issued: 05/13/1997
• Est. Priority Date: 07/14/1993
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Moberg, Sheldon B., Causey, James D. III
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Parker, Marianne
• Application Number:
  US08/091,636
• Time in Patent Office: 1,399 Days
• Field of Search: 128/642, 128/695, 128/714, 128/782, 607/9, 607/19, 607/20, 607/23, 607/24, 607/119, 607/122, 607/129
• US Class Current: 607/122
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/36578 controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

Implantable leads incorporating accelerometer-based cardiac wall motion sensors, and a method of fabricating such leads, are provided. The cardiac wall motion sensors transduce accelerations of cardiac tissue to provide electrical signals indicative of cardiac wall motion to an implantable cardiac stimulating device. The implantable cardiac stimulating device may use the electrical signals indicative of cardiac wall motion to detect and discriminate among potentially malignant cardiac arrhythmias. In response to a detected abnormal cardiac rhythm, the cardiac stimulating device may deliver therapeutic electrical stimulation to selected regions of cardiac tissue.

Claims

1. An implantable lead for use with an implantable cardiac stimulation device, said implantable lead comprising:

cardiac wall acceleration sensing means for providing a signal indicative of acceleration of a cardiac wall;

endocardial carrier means for transvenously positioning said cardiac wall acceleration sensing means with respect to said cardiac wall so that said cardiac wall acceleration sensing means is responsive to said acceleration of said cardiac wall, said endocardial carrier means having a substantially elongated lead body with a distal end for contacting said cardiac wall and a proximal end;

conductor means, within said lead body, for conducting said signal indicative of acceleration of a cardiac wall from said cardiac wall acceleration sensing means to said implantable cardiac stimulation device; and

connector means for electrically interfacing said conductor means at said proximal end of said lead body to said implantable cardiac stimulation device.

2. The implantable lead of claim 1, wherein said cardiac wall acceleration sensing means comprises an accelerometer.

3. The implantable lead of claim 2, wherein said cardiac wall sensing means further comprises local signal processing means for locally processing said signal indicative of said accelerations.

4. The implantable lead of claim 2, wherein said accelerometer comprises means for transducing accelerations of said cardiac wall in directions along two perpendicular axes.

5. The implantable lead of claim 4, wherein said conductor means comprises two wires for conducting said signal indicative of said accelerations to said implantable cardiac stimulation device.

6. The implantable lead of claim 2, wherein said accelerometer comprises:

a mounting surface;

a first cantilever beam having a free end, an end affixed to said mounting surface, and a planar surface, said first cantilever beam comprising a material having an electrical characteristic that varies measurably when a mechanical stress or strain is exerted on said material to provide said signal indicative of said accelerations; and

a first mass disposed on said free end of said first cantilever beam for inducing a mechanical stress or strain in said material of said first cantilever beam when said first mass is accelerated.

7. The implantable lead of claim 6, wherein:

said first mass is disposed on said free end of said first cantilever beam so as to be offset with respect to said planar surface, so that a mechanical stress or strain is exerted on said material in response to accelerations along a first axis extending from said fixed end to said free end of said first cantilever beam and in response to accelerations along a second axis perpendicular to said planar surface of said first cantilever beam; and

said conductor means comprises two wires for conducting said signal to said implantable cardiac stimulation device.

8. The implantable lead of claim 6, wherein said material comprises a piezoelectric material that generates electrical potentials indicative of said accelerations.

9. The implantable lead of claim 6, wherein said accelerometer further comprises:

a second cantilever beam having a free end, an end affixed to said mounting surface, and a planar surface, said second cantilever beam comprising said material having an electrical characteristic that varies measurably when a mechanical stress or strain is exerted on said material to provide said signal indicative of said accelerations, wherein said second cantilever beam is positioned with respect to said first cantilever beam so as to be responsive to accelerations of said cardiac wall to which said first cantilever beam is substantially nonresponsive; and

a second mass disposed on said free end of said second cantilever beam for inducing a mechanical stress or strain in said material of said second cantilever beam when said second mass is accelerated.

10. The implantable lead of claim 9, wherein said second cantilever beam is affixed to said mounting surface so that said planar surface of said second cantilever beam is orthogonal to said planar surface of said first cantilever beam, and said second cantilever beam is responsive to accelerations along a third axis perpendicular to said planar surface of said second cantilever beam.

11. The implantable lead of claim 2, wherein:

said implantable lead further comprises electrode means disposed at said distal end of said lead body, for delivering therapeutic electrical stimulation to cardiac tissue, said implantable lead further comprises fixation means for fixating the electrode means against said cardiac wall;

said conductor means comprises means for conducting stimulation pulses from the implantable cardiac stimulation device to said electrode means and for sensing cardiac electrical activity; and

said accelerometer is disposed at the distal end of said lead body, proximate to said cardiac wall, so that said accelerometer is securely attached to said cardiac wall by said fixation means.

12. The implantable lead of claim 11, wherein said conductor means comprises a wire shared by said electrode means and said accelerometer, for connecting said electrode means and said accelerometer to said implantable cardiac stimulation device.

13. The implantable lead of claim 11, wherein said accelerometer is disposed within a housing at said distal end of said implantable lead.

14. The implantable lead of claim 13, wherein said electrode means comprises a ring electrode and said housing includes said ring electrode.

15. The implantable lead of claim 14, wherein said housing includes a distal end and a proximal end, said housing further comprising:

a plug at said distal end of said housing; and

a hermetic feedthrough at said proximal end of said housing for hermetically sealing said accelerometer within said housing.

16. The implantable lead of claim 15, wherein:

said accelerometer has an output terminal and a ground terminal;

said ground terminal of said accelerometer being electrically connected to said ring terminal;

said conductor means comprises a first and a second wire for connecting the output and ground terminals, respectively, of said accelerometer to said implantable cardiac stimulation device; and

said hermetic feedthrough comprises a terminal for connecting said first wire to said accelerometer.

17. The implantable lead of claim 1, wherein:

said cardiac wall acceleration sensing means comprises a plurality of accelerometers for providing a plurality of signals indicative of accelerations of said cardiac wall; and

said conductor means comprises means for conducting said plurality of signals indicative of accelerations of said cardiac wall to said implantable cardiac stimulation device.

18. A method of fabricating an implantable lead incorporating a cardiac wall acceleration sensor that provides a signal indicative of cardiac wall acceleration, said method comprising the steps of:

providing an endocardial lead body for transvenous attachment to a cardiac wall;

disposing said cardiac wall acceleration sensor within a distal end of said endocardial lead body so that said cardiac wall acceleration sensor responds to acceleration of said cardiac wall and provides said signal indicative of cardiac wall acceleration;

attaching a connector to said endocardial lead body to permit said endocardial lead body to be connected to an implantable cardiac stimulation device; and

electrically connecting said cardiac wall acceleration sensor to said connector.

19. The method of claim 18, wherein:

said method further comprises the step of mounting a ring electrode to a distal end of said substantially elongated lead body; and

said disposing step further comprises disposing said accelerometer within said ring electrode.

20. The method of claim 19, further comprising the step of hermetically sealing said accelerometer in a housing formed by said ring electrode, a plug disposed at a distal end of said ring electrode, and a hermetic feedthrough disposed at a proximal end of said ring electrode.

21. An implantable endocardial lead for use with an implantable cardiac stimulation device, said implantable lead comprising:

acceleration sensing means for providing acceleration signals;

an elongated lead body having a distal end for contacting the cardiac muscle tissue and a proximal end, said lead body having a connector at said proximal end for interfacing with said implantable stimulation device, said lead body further having said acceleration sensing means disposed within said distal end; and

conductor means, within said lead body, for conducting said acceleration signal from said acceleration sensing means to said implantable cardiac stimulation device;

whereby when said elongated lead body is transvenously implanted said acceleration sensing means is positioned so as to be responsive to accelerations of the cardiac muscle tissue corresponding to cardiac mechanical activity.

22. The implantable lead of claim 21, further comprising:

electrode means, disposed at said distal end of said lead body, for delivering stimulation pulses to cardiac tissue and for sensing cardiac electrical activity;

said conductor means further including means for conducting stimulation pulses from and receiving cardiac electrical signals to said implantable cardiac stimulation device.

23. The implantable lead of claim 21, wherein said acceleration sensing means comprises means for transducing accelerations of the cardiac muscle tissue in directions along two perpendicular axes.

24. The implantable lead of claim 21, wherein said acceleration sensing means comprises:

a mounting surface;

a first cantilever beam having a free end, an end affixed to said mounting surface, and a planar surface, said first cantilever beam comprising a material having an electrical characteristic that varies measurably when a mechanical stress or strain is exerted on said material to provide said signal indicative of said accelerations; and

a first mass disposed on said free end of said first cantilever beam for inducing a mechanical stress or strain in said material of said first cantilever beam when said first mass is accelerated.

25. The implantable lead of claim 24, wherein:

said first mass is disposed on said free end of said first cantilever beam so as to be offset with respect to said planar surface, so that a mechanical stress or strain is exerted on said material in response to accelerations along a first axis extending from said fixed end to said free end of said first cantilever beam and in response to accelerations along a second axis perpendicular to said planar surface of said first cantilever beam; and

said conductor means comprises two wires for conducting said signal to said implantable cardiac stimulation device.

26. The implantable lead of claim 25, wherein said material comprises one of a piezoelectric material or a piezoresistive material.

27. The implantable lead of claim 25, wherein said acceleration sensing means further comprises:

a second cantilever beam having a free end, an end affixed to said mounting surface, and a planar surface, said second cantilever beam comprising said material having an electrical characteristic that varies measurably when a mechanical stress or strain is exerted on said material to provide said signal indicative of said accelerations, wherein said second cantilever beam is positioned with respect to said first cantilever beam so as to be responsive to accelerations of said cardiac muscle tissue to which said first cantilever beam is substantially nonresponsive; and

a second mass disposed on said free end of said second cantilever beam for inducing a mechanical stress or strain in said material of said second cantilever beam when said second mass is accelerated.

28. The implantable lead of claim 27, wherein:

said second cantilever beam is affixed to said mounting surface so that said planar surface of said second cantilever beam is orthogonal to said planar surface of said first cantilever beam, and said second cantilever beam is responsive to accelerations along a third axis perpendicular to said planar surface of said second cantilever beam.

29. The implantable lead of claim 21, wherein said conductor means comprises a wire shared by said electrode means and said accelerometer, for connecting said electrode means and said acceleration sensing means to said implantable cardiac stimulation device.

30. The implantable lead of claim 29, wherein:

said electrode means includes a tip and a ring electrode;

said accelerometer has an output terminal and a ground terminal, said ground terminal being electrically connected to said ring electrode;

said conductor means comprises a first, a second, and a third wire for connecting the output and ground terminals, respectively, of said accelerometer to said implantable cardiac stimulation device, said second wire being the shared wire between the ring electrode and the ground terminal of said accelerometer; and

said hermetic feedthrough comprises a terminal for connecting said first wire to said accelerometer.