Electrochemical sensor
DC CAFCFirst Claim
1. An electrode strip for use in an electrochemical sensor for measuring a compound in a sample, comprising:
- an electrode support;
a reference or counter electrode disposed on the electrode support;
a working electrode spaced from the reference or counter electrode on the electrode support and comprising an enzyme which catalyzes a reaction involving a substrate for said enzyme or a substrate catalytically reactive with an enzyme and a mediator which transfers electrons between said enzyme-catalyzed reaction and said working electrode to create a current representative of the activity of said enzyme and representative of the compound;
a covering layer defining an enclosed space over the reference and working electrodes, said covering layer having an aperture for receiving a sample into said enclosed space; and
a plurality of mesh layers interposed in said enclosed space between said covering layer and said electrodes.
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Abstract
An electrode strip for use in an electrochemical sensor for measuring a compound in a sample is provided, including an electrode support, a reference or counter electrode disposed on the support, a working electrode spaced from the reference or counter electrode on the support, a covering layer defining an enclosed space over the reference and working electrodes and having an aperture for receiving a sample into the enclosed space, and a plurality of mesh layers interposed in the enclosed space between the covering layer and the support, the covering layer having a sample application aperture spaced from said electrodes and said reference electrode spaced from said working electrode at a position remote from and on the opposite side of said working electrode from said aperture. The working electrode includes an enzyme capable of catalyzing a reaction involving a substrate for the enzyme or a substrate catalytically reactive with an enzyme and a mediator capable of transferring electrons transferred between the enzyme-catalyzed reaction and the working electrode to create a current representative of the activity of the enzyme and representative of the compound.
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Citations
21 Claims
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1. An electrode strip for use in an electrochemical sensor for measuring a compound in a sample, comprising:
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an electrode support; a reference or counter electrode disposed on the electrode support; a working electrode spaced from the reference or counter electrode on the electrode support and comprising an enzyme which catalyzes a reaction involving a substrate for said enzyme or a substrate catalytically reactive with an enzyme and a mediator which transfers electrons between said enzyme-catalyzed reaction and said working electrode to create a current representative of the activity of said enzyme and representative of the compound; a covering layer defining an enclosed space over the reference and working electrodes, said covering layer having an aperture for receiving a sample into said enclosed space; and a plurality of mesh layers interposed in said enclosed space between said covering layer and said electrodes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An electrode strip for use in an electrochemical sensor for measuring a compound in a sample, comprising:
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an elongated electrode support defining a sample transfer path for directional flow of the sample from an application point along said electrode support; a working electrode in said sample transfer path said working electrode comprising an enzyme which catalyzes a reaction involving a substrate for said enzyme or a substrate catalytically reactive with an enzyme and a mediator which transfers electrons between said enzyme-catalyzed reaction and said working electrode to create a current representative of the activity of said enzyme and representative of the compound; a reference or counter electrode in said sample transfer path; and a covering layer defining an enclosed space over the sample transfer path, the reference or counter electrode and said working electrode, said covering layer having an aperture for receiving sample into said enclosed space; said aperture spaced away from and upstream of said electrodes in said sample transfer path and said reference or counter electrode spaced downstream of said working electrode in said sample transfer path. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification