Ventricular defibrillation by coordination of shocks with sensed coarse VF complexes

• US 5,632,766 A
• Filed: 08/11/1995
• Issued: 05/27/1997
• Est. Priority Date: 08/11/1995
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Lin, Yayun, Hsu, William
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US08/513,685
• Time in Patent Office: 655 Days
• Field of Search: 607/4, 607/5
• US Class Current: 607/5
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

A method and system for ventricular defibrillation by coordinating the delivery of defibrillation shocks with sensed ventricular fibrillation complexes in a way which improves the probability of success of the defibrillation shock. Ventricular electrical activity is monitored during VF to detect coarse VF complexes. The defibrillation shock is delivered in coordination with the occurrence of coarse VF complexes, and specifically to occur on the upslope portion thereof, for optimal probability of success. Preferably, DF shock is delivered on the nth occurring coarse VF complex, wherein n is equal to or greater than 2 and less than or equal to about 9.

Claims

1. A method of treating ventricular fibrillation, comprising the steps of:

a) monitoring a signal representative of ventricular electrical activity during a period of ventricular fibrillation;

b) detecting in the monitored signal, the occurrence of coarse VF complexes;

c) analyzing coarse VF to determine upslope; and

d) delivering a DF shock during the upslope portion of a complex.

2. A method according to claim 1, including the step of counting occurrences of coarse VF complexes, and coordinating the delivery of the DF shock with the upslope of a predetermined numbered occurrence of coarse VF complex.

3. The method of claim 1 wherein the step of monitoring comprises monitoring the morphology signal, across proximal and distal shocking coils of an endocardial lead, and wherein the step of delivering a DF shock includes applying a pulse of electrical energy to the endocardial lead.

4. The method of claim 1 wherein the steps of detecting and analyzing the occurrence of a coarse VF complex includes sensing when the amplitude of the VF signal is greater than a predetermined value with a positive slope or rate of change.

5. The method of claim 1 wherein the step of delivering a DF shock includes timing the shock based on when the amplitude of the VF signal is greater than a predetermined value and has a positive slope or rate of change.

6. A method of treating ventricular fibrillation, comprising the steps of:

a) monitoring a signal representative of ventricular electrical activity during a period of ventricular fibrillation;

b) detecting and counting the occurrence of coarse VF complexes; and

c) delivering a DF shock during the nth counted complex, where n is a number greater than or equal to 2 and less than or equal to about 9.

7. The method of claim 6 wherein the step of monitoring comprises monitoring the morphology signal, between proximal and distal shocking coils, of an endocardial lead, and wherein the step of delivering a DF shock includes applying a pulse of electrical energy to the endocardial lead.

8. The method of claim 6 wherein the step of detecting the occurrence of a coarse VF complex includes sensing when the amplitude of the VF signal is greater than a predetermined value with a positive slope or rate of change.

9. The method of claim 6 wherein the step of delivering a DF shock on the nth complex includes timing the shock based on when the amplitude of the VF signal is greater than a predetermined value and has a positive slope or rate of change.

10. A method of treating ventricular fibrillation, comprising the steps of:

a) monitoring a signal representative of ventricular electrical activity during a period of ventricular fibrillation;

b) detecting the occurrence of coarse VF complexes;

c) analyzing coarse VF complexes to determine upslope; and

d) delivering a DF shock during the upslope of the nth counted complex, where n is a number greater than or equal to 2 and less than or equal to about 9.

11. A method according to claim 10 wherein the step of analyzing includes counting coarse VF complexes.

12. The method of claim 10 wherein the step of monitoring comprises monitoring the morphology signal, between proximal and distal shocking coils, of an endocardial lead, and wherein the step of delivering a DF shock includes applying a pulse of electrical energy to the endocardial lead.

13. The method of claim 10 wherein the steps of detecting and analyzing the occurrence of a coarse VF complex includes sensing when the amplitude of the VF signal is greater than a predetermined value with a positive slope or rate of change.

14. The method of claim 10 wherein the step of delivering a DF shock on the nth complex includes timing the shock based on when the amplitude of the VF signal is greater than a predetermined value and has a positive slope or rate of change.

19. A method according to claim 10 further including the step of delivering at least one asynchronous DF shock if the VF is not terminated by the delivery of coordinated DF shocks.

15. A method of determining when to deliver a DF shock to a heart in ventricular fibrillation, comprising the steps of:

a) monitoring a signal representative of ventricular electrical activity during a period of ventricular fibrillation;

b) detecting the occurrence of coarse VF complexes as intervals of increase of the absolute value of the monitored signal; and

c) selecting the time for DF shock delivery based on when the absolute value of the monitored VF signal reaches a predetermined value during a period of increasing rate.

16. A method of determining when to deliver a DF shock to a heart in ventricular fibrillation, comprising the steps of:

a) monitoring a signal representative of ventricular electrical activity during a period of ventricular fibrillation;

b) measuring the amplitude of the monitored signal;

c) determining the rate of change of the amplitude of the monitored signal; and

d) selecting the time for DF shock delivery based on the amplitude of the monitored signal, a predetermined value during fibrillation, and whether the rate of change of the amplitude is positive.

17. A method of claim 16 wherein the step of measuring includes repeated sampling of the monitored signal, and the step of determining rate of change includes comparing samples of the monitored signal over a small increment of time.

18. A method of treating ventricular fibrillation, comprising the steps of:

a) monitoring a heart signal representative of ventricular electrical activity;

b) detecting the presence of ventricular fibrillation

c) during VF, detecting the occurrence of coarse VF complexes by measuring the monitored signal; and

d) for the nth coarse VF complex, where n is greater than or equal to 2 and less than or equal to 9, delivering a coordinated DF shock based on the a predetermined value for the amplitude of the monitored signal, and whether the amplitude has a positive the rate of change.

20. A defibrillator, comprising:

a lead system for placement in electrical contact with the ventricle of the heart;

a sensing system, attached to the lead system for monitoring ventricular electrical activity, which detects the presence of VF, and during VF to detect coarse VF complexes;

a DF control system for controlling delivery of DF shocks through the lead system to the ventricle, the control system responsive to the sensing system to deliver a DF shock when the sensed VF complex increases to a predetermined value with a positive rate of change.

21. The defibrillator according to claim 20 wherein the DF control system comprises a counting subsystem which counts the occurrence of VF complexes, and the DF control system delivers a DF shock coordinated with the nth coarse complex, where n is greater than or equal to 2 and less than or equal to about 9.

22. The defibrillator according to claim 21 wherein the DF control system delivers the coordinated shocks during an interval following onset of VF, and at least one asynchronous DF shock if the VF is not terminated by the coordinated shocks.