Syringe-cum-container

• US 5,637,100 A
• Filed: 10/03/1995
• Issued: 06/10/1997
• Est. Priority Date: 11/27/1992
• Status: Expired due to Term

• Current Assignee: Daikyo Seiko, Ltd.
• Original Assignee: Daikyo Seiko, Ltd.
• Inventors: Sudo, Morihiro
• Primary Examiner(s): Millin, Vincent
• Assistant Examiner(s): GRING, NOELLE K
• Application Number:
  US08/538,379
• Time in Patent Office: 616 Days
• Field of Search: 604/82, 604/89, 604/90, 604/92, 604/191, 604/218, 604/238, 604/181, 604/187
• US Class Current: 604/238
• CPC Class Codes: A61M 2005/3118 via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
• CPC Class Codes: A61M 2005/3121 via the proximal end of a syringe, i.e. syringe end opposite to needle cannula mounting end
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 2005/3139 Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence

Abstract

An improved syringe is provided which can be used in any step of preparation of a medicament by vacuum freeze-drying, etc., storage of a medicament, mixing of medicaments and dosing of a medicament in a sanitary and stable manner. The syringe comprises a cylinder having a front end part at one end and an opening part at another end and a bypass running in the longitudinal direction near the central position of the cylinder on the inner wall within the cylinder. A first sealing stopper is adapted, at a position toward the opening part of the cylinder from the bypass within the cylinder, to form a first compartment between the front end of the cylinder and the first sealing stopper. A second sealing is stopper adapted, at a position toward the opening part of the cylinder from the first sealing stopper within the cylinder, to form a second compartment between the first sealing stopper and second sealing stopper. One or more bypasses are provided in a concave form on the inner wall surface of the cylinder, and the outer circumference of the cylinder has a smooth cylindrical shape. Further one or more bypasses can be provided in a concave form in two stages on the inner wall surface of the cylinder.

Claims

1. A syringe comprising:

a cylinder having a first end and a second end, said second end being an open end;

first and second sealing stoppers slidably mounted in said cylinder, said first sealing stopper being disposed between said second sealing stopper and said first end of said cylinder, whereby a first compartment is formed between said first sealing stopper and said first end of said cylinder and a second compartment is formed between said first and second sealing stoppers;

at least one longitudinally elongated first bypass formed in an inner wall surface of said cylinder at a location intermediate said first and second ends of said cylinder, said first bypass being formed by a concave groove, and said cylinder having a smooth cylindrical shape at a location of an outer wall surface thereof corresponding to a location of said first bypass formed in said inner wall surface;

at least one longitudinally elongated second bypass formed in an inner wall surface of said cylinder at a location substantially adjacent said second end of said cylinder, said second bypass being formed by a concave groove, and said cylinder having a smooth cylindrical shape at a location of an outer wall surface thereof corresponding to a location of said second bypass formed in said inner wall surface;

wherein said second bypass has a length greater than a longitudinal thickness of said first sealing stopper; and

wherein said cylinder has an uninterrupted uniform outer diameter extending from a position adjacent said first end of said cylinder to an extreme end of said second end of said cylinder.

2. A syringe as recited in claim 1, wherein

said second bypass has a length of one-third to one times a longitudinal thickness of said first sealing stopper.

3. A syringe as recited in claim 1, wherein

said at least one first bypass comprises a plurality of first bypasses;

and

said at least one second bypass comprises a plurality of second bypasses.

4. A syringe as recited in claim 1, wherein

said at least one first bypass comprises a plurality of first bypasses.

5. A syringe as recited in claim 1, further comprising

a removable cap fit over said open second end of said cylinder.

6. A syringe comprising:

a cylinder having a first end and a second end, said second end being an open end;

first and second sealing stoppers slidably mounted in said cylinder, said first sealing stopper being disposed between said second sealing stopper and said first end of said cylinder, whereby a first compartment is formed between said first sealing stopper and said first end of said cylinder and a second compartment is formed between said first and second sealing stoppers;

at least one longitudinally elongated first bypass formed in an inner wall surface of said cylinder at a location intermediate said first and second ends of said cylinder, said first bypass being formed by a concave groove, and said cylinder having a smooth cylindrical shape at a location of an outer wall surface thereof corresponding to a location of said first bypass formed in said inner wall surface;

a finger-engaging flange member removably fit over said open second end of said cylinder, said finger-engaging flange member having a central plunger-receiving opening formed therein;

at least one longitudinally elongated second bypass formed in an inner wall surface of said cylinder at a location substantially adjacent said second end of said cylinder, said second bypass being formed by a concave groove, and said cylinder having a smooth cylindrical shape at a location of an outer wall surface thereof corresponding to a location of said second bypass formed in said inner wall surface;

wherein said second bypass has a length greater than a longitudinal thickness of said first sealing stopper; and

wherein said finger-engaging flange member has a radially inwardly projecting portion, and said cylinder has a recess in the outer wall surface thereof adjacent said second open end, said inwardly projecting portion being engageable in said recess.

7. A syringe as recited in claim 6, further comprising

a removable cap fittable over said open second end of said cylinder when said finger-engaging flange member is removed.

8. A syringe as recited in claim 7, wherein

said removable cap has a radially inwardly projecting portion, said inwardly projecting portion being engageable in said recess.

9. A syringe as recited in claim 6, wherein

said second bypass has a length of one-third to one times a longitudinal thickness of said first sealing stopper.

10. A syringe as recited in claim 6, wherein

said at least one first bypass comprises a plurality of first bypasses;

and

said at least one second bypass comprises a plurality of second bypasses.

11. A syringe as recited in claim 6, wherein

said at least one first bypass comprises a plurality of first bypasses.

12. A syringe comprising:

a cylinder having a first end and a second end, said second end being an open end;

first and second sealing stoppers slidably mounted in said cylinder, said first sealing stopper being disposed between said second sealing stopper and said first end of said cylinder, whereby a first compartment is formed between said first sealing stopper and said first end of said cylinder and a second compartment is formed between said first and second sealing stoppers;

at least one longitudinally elongated first bypass formed in an inner wall surface of said cylinder at a location intermediate said first and second ends of said cylinder, said first bypass being formed by a concave groove, and said cylinder having a smooth cylindrical shape at a location of an outer wall surface thereof corresponding to a location of said first bypass formed in said inner wall surface;

at least one longitudinally elongated second bypass formed in an inner wall surface of said cylinder at a location substantially adjacent said second end of said cylinder, said second bypass being formed by a concave groove, and said cylinder having a smooth cylindrical shape at a location of an outer wall surface thereof corresponding to a location of said second bypass formed in said inner wall surface;

a rubber stopper fit in said first end of said cylinder, said rubber stopper having a central recess opening in a direction away from said second end of said cylinder, such that said rubber stopper has a U-shaped longitudinal cross section; and

wherein said second bypass has a length greater than a longitudinal thickness of said first sealing stopper.

13. A syringe as recited in claim 12, further comprising

a needle-retaining cap fit over an open end of said recess of said rubber stopper.

14. A syringe as recited in claim 13, further comprising

a needle fitting tube interposed between said first end of said cylinder and said needle-retaining cap and connecting said needle-retaining cap to said first end of said cylinder.

15. A syringe as recited in claim 12, wherein

said at least one first bypass comprises a plurality of first bypasses;

and

said at least one second bypass comprises a plurality of second bypasses.