Method and apparatus for ultrasonic medical treatment with optimum ultrasonic irradiation control

• US 5,643,179 A
• Filed: 12/28/1994
• Issued: 07/01/1997
• Est. Priority Date: 12/28/1993
• Status: Expired due to Term

• Current Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Original Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: Fujimoto, Katsuhiko
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): MANTIS MERCADER, ELENI M
• Application Number:
  US08/365,149
• Time in Patent Office: 916 Days
• Field of Search: 128/660.03, 601/2, 601/3, 601/4, 607/97
• US Class Current: 601/2
• CPC Class Codes: A61B 2017/00106 ultrasonic
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

An ultrasonic medical treatment scheme for optimally controlling the irradiation energy of the intense ultrasonic waves. In this scheme, an ultrasonic energy of the ultrasonic waves irradiated at a tissue boundary surface such as a body surface is obtained, and at least one of the driving power and the irradiation time of the ultrasonic wave generation source in the applicator is controlled such that the ultrasonic energy at the tissue boundary surface becomes less than a prescribed threshold which is determined in view of an influence on the tissue boundary surface due to the ultrasonic waves. In addition, the ultrasonic energy of the ultrasonic waves irradiated at a focal point of the ultrasonic waves can also be obtained and the applicator can be controlled such that the ultrasonic energy at the focal point becomes greater than another prescribed threshold determined in view of a medical treatment effect at the focal point due to the ultrasonic waves at the same time.

Claims

1. An ultrasonic medical treatment apparatus, comprising:

an applicator having an ultrasonic wave generation source for irradiating ultrasonic waves to a treatment target portion within a body to be examined;

energy obtaining means for obtaining an ultrasonic energy of the ultrasonic waves irradiated at a tissue boundary surface of the body to be examined; and

control means for controlling the applicator such that the ultrasonic energy at the tissue boundary surface obtained by the energy obtaining means becomes less than a prescribed threshold.

2. The apparatus of claim 1, wherein the control means uses the prescribed threshold which is determined in view of an influence on the tissue boundary surface due to the ultrasonic waves.

3. The apparatus of claim 2, wherein the control means uses the prescribed threshold which is determined as a limit for causing a damage on the tissue boundary surface due to heating by the ultrasonic waves.

4. The apparatus of claim 1, wherein the energy obtaining means obtains the ultrasonic energy of the ultrasonic waves irradiated at the tissue boundary surface which is a body surface of the body to be examined.

5. The apparatus of claim 1, wherein the control means controls the applicator by controlling at least one of a driving power and an ultrasonic wave irradiation time of the ultrasonic wave generation source in the applicator.

6. The apparatus of claim 1, wherein the tissue boundary surface is a body surface of the body to be examined, and the control means controls the applicator by controlling at least one of a driving power and an ultrasonic wave irradiation time of the ultrasonic wave generation source in the applicator to satisfy the following condition:

space="preserve" listing-type="equation">I.sub.S ×

t.sub.S ×

f<

124 [MHz·

J/cm.sup.2 ]

where I_S is an ultrasonic wave intensity at the body surface, t_S is the ultrasonic wave irradiation time, and f is a frequency of the ultrasonic waves irradiated from the applicator.

7. The apparatus of claim 1, wherein the energy obtaining means calculates the ultrasonic energy irradiated at the tissue boundary surface according to a focusing level, a frequency, and a focal point depth with respect to the tissue boundary surface of the ultrasonic waves irradiated from the applicator.

8. The apparatus of claim 1, wherein the energy obtaining means also obtains an ultrasonic energy of the ultrasonic waves irradiated at a focal point of the ultrasonic waves, and the control means controls the applicator such that the ultrasonic energy at the tissue boundary surface obtained by the energy obtaining means becomes less than a first the prescribed threshold and the ultrasonic energy at the focal point obtained by the energy obtaining means becomes greater than another prescribed threshold.

9. The apparatus of claim 8, wherein the control means uses the prescribed threshold which is determined in view of an influence on the tissue boundary surface due to the ultrasonic waves and the another prescribed threshold which is determined in view of a medical treatment effect at the focal point due to the ultrasonic waves.

10. The apparatus of claim 9, wherein the control means uses the prescribed threshold which is determined as a limit for causing a damage on the tissue boundary surface due to heating by the ultrasonic waves, and the another prescribed threshold which is determined as a limit for achieving a sufficient medical treatment effect on the treatment target portion located at the focal point of the ultrasonic waves.

11. A method of ultrasonic medical treatment, comprising the steps of:

irradiating ultrasonic waves from an applicator having an ultrasonic wave generation source to a treatment target portion within a body to be examined;

obtaining an ultrasonic energy of the ultrasonic waves irradiated at a tissue boundary surface of the body to be examined; and

controlling the applicator such that the ultrasonic energy at the tissue boundary surface obtained at the obtaining step becomes less than a prescribed threshold.

12. The method of claim 11, wherein the prescribed threshold is determined in view of an influence on the tissue boundary surface due to the ultrasonic waves.

13. The method of claim 12, wherein the prescribed threshold is determined as a limit for causing a damage on the tissue boundary surface due to heating by the ultrasonic waves.

14. The method of claim 11, wherein the tissue boundary surface is a body surface of the body to be examined.

15. The method of claim 11, wherein the controlling step controls the applicator by controlling at least one of a driving power and an ultrasonic wave irradiation time of the ultrasonic wave generation source in the applicator.

16. The method of claim 11, wherein the tissue boundary surface is a body surface of the body to be examined, and the controlling step controls the applicator by controlling at least one of a driving power and an ultrasonic wave irradiation time of the ultrasonic wave generation source in the applicator to satisfy the following condition:

space="preserve" listing-type="equation">I.sub.S ×

t.sub.S ×

f<

124 [MHz·

J/cm.sup.2 ]

where I_S is an ultrasonic wave intensity at the body surface, t_S is the ultrasonic wave irradiation time, and f is a frequency of the ultrasonic waves irradiated from the applicator.

17. The method of claim 11, wherein the obtaining step calculates the ultrasonic energy irradiated at the tissue boundary surface according to a focusing level, a frequency, and a focal point depth with respect to the tissue boundary surface of the ultrasonic waves irradiated from the applicator.

18. The method of claim 11, wherein the obtaining step also obtains an ultrasonic energy of the ultrasonic waves irradiated at a focal point of the ultrasonic waves, and the controlling step controls the applicator such that the ultrasonic energy at the tissue boundary surface obtained at the obtaining step becomes less than the prescribed threshold and the ultrasonic energy at the focal point obtained at the obtaining step becomes greater than another prescribed threshold.

19. The method of claim 18, wherein the first prescribed threshold is determined in view of an influence on the tissue boundary surface due to the ultrasonic waves while the another prescribed threshold is determined in view of a medical treatment effect at the focal point due to the ultrasonic waves.

20. The method of claim 19, wherein the prescribed threshold is determined as a limit for causing a damage on the tissue boundary surface due to heating by the ultrasonic waves, while the another prescribed threshold is determined as a limit for achieving a sufficient medical treatment effect on the treatment target portion located at the focal point of the ultrasonic waves.