Apparatus for collection washing and reinfusion of shed blood

• US 5,643,193 A
• Filed: 12/13/1995
• Issued: 07/01/1997
• Est. Priority Date: 12/13/1995
• Status: Expired due to Term

• Current Assignee: Haemonetics Corporation
• Original Assignee: Haemonetics Corporation
• Inventors: Pages, Etienne, Papillon, Jean
• Primary Examiner(s): Weiss, John G.
• Assistant Examiner(s): O YONG, KI
• Application Number:
  US08/571,496
• Time in Patent Office: 566 Days
• Field of Search: 604/4, 604/5, 604/6
• US Class Current: 604/6.07
• CPC Class Codes: A61M 1/0209 Multiple bag systems for separating or storing blood components
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/3692 Washing or rinsing blood or blood constituents
• CPC Class Codes: A61M 1/3693 using separation based on different densities of components, e.g. centrifuging
• CPC Class Codes: A61M 1/3696 with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
• CPC Class Codes: A61M 1/604 Bag or liner in a rigid container, with suction applied to both
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3351 Controlling upstream pump pressure
• CPC Class Codes: A61M 2205/3393 by weighing the reservoir
• CPC Class Codes: B04B 2005/0478 with filters in the separation chamber

Abstract

An integrated, vacuum-driven shed blood processing system that collects, dilutes, filters and washes postoperatively shed blood and concentrates red blood cells for reinfusion to the patient. The location of the centrifuge bowl between the surgical site and the vacuum source used to clean the site allows the immediate collection of shed blood in the bowl without an intermediate reservoir or an additional pump. In conjunction with a modified centrifuge bowl having a sealed aperture in its floor that permits reinfusion directly from the bowl without an additional reinfusion bag or reverse pump, this configuration processes blood for reinfusion using fewer steps and components yet without loss of functionality. Dilution of the blood upon its introduction into the system reduces the tendency to coagulate and allows the use of lower bowl rotation speeds. Slower rotation reduces red blood cell damage and lowers power requirements, which improves portability.

Claims

1. An apparatus for processing blood from a surgical site on a patient, the apparatus comprising:

a. a centrifuge, for separating the blood into a plurality of components and isolating at least one of the components, the centrifuge comprising

i. a centrifuge bowl having an inlet port, a floor, a separation chamber, and an outlet port through which fluid exits the centrifuge bowl; and

ii. means for rotating the centrifuge bowl;

b. a receptacle for receiving fluid from the outlet port;

c. a first conduit for conveying blood from the site to the inlet port;

d. a second conduit for conveying fluid from the outlet port to the receptacle; and

e. a vacuum source, coupled to the separation chamber through the interior of the receptacle.

2. The apparatus of claim 1 wherein the centrifuge bowl comprises a filter positioned between the inlet port and the separation chamber.

3. The apparatus of claim 1 further comprising:

a. a source of washing solution; and

b. a third conduit, fluidly coupled to the first conduit, for conveying the washing solution from the source of washing solution into the first conduit so as to dilute the blood therein before the blood enters the centrifuge bowl.

4. The apparatus of claim 3 wherein the third conduit is configured to convey washing solution to the first conduit so that washing solution and blood are present in the first conduit at a volume ratio of at least 1.5 to 1.

5. The apparatus of claim 3 further comprising a flow restricter disposed in the third conduit.

6. The apparatus of claim 3 wherein the washing solution contains an anticoagulant.

7. The apparatus of claim 1 wherein the floor is constructed so as to allow the optional formation of an aperture therein for extraction of a blood component from the separation chamber.

8. The apparatus of claim 7 further comprising means for returning the blood from the aperture to the patient.

9. The apparatus of claim 3 wherein the means for rotating the centrifuge bowl is configured to operate the centrifuge bowl at a rate lower than 4000 rpm.

10. The apparatus of claim 3 wherein the first conduit has a length and the washing solution and the blood enter the first conduit at the same point along the length.

11. The apparatus of claim 1 further comprising a controller for operating at least one of the centrifuge and the vacuum source on the basis of at least one of:

a. negative pressure in the first or second conduit or in the receptacle;

b. weight of the receptacle;

c. volume of red blood cells in the separation chamber; and

d. presence or absence of red blood cells in the second conduit.

12. The apparatus of claim 9 wherein the means for rotating the centrifuge bowl is configured to operate the bowl at a rate between 2000 and 3000 rpm.

13. The apparatus of claim 2 wherein the centrifuge bowl further comprises an inlet tube extending into the bowl from the inlet port, the inlet tube supporting the filter.

14. The apparatus of claim 4 further comprising a flow restricter disposed in the third conduit, whereby the third conduit is configured to convey washing solution to the first conduit so that washing solution and blood are present in the first conduit at the ratio.