Nozzle assembly having a frangible plunger

• US 5,643,211 A
• Filed: 02/29/1996
• Issued: 07/01/1997
• Est. Priority Date: 02/29/1996
• Status: Expired due to Fees

• Current Assignee: Antares Pharma Incorporated
• Original Assignee: Medi-Ject Corporation
• Inventors: Sadowski, Peter, Mulhauser, Paul, Schiff, David
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US08/608,799
• Time in Patent Office: 488 Days
• Field of Search: 604/110, 604/187, 604/218, 604/228
• US Class Current: 604/110
• CPC Class Codes: A61M 2005/31516 reducing dead-space in the syringe barrel after delivery
• CPC Class Codes: A61M 2005/5073 by breaking or rupturing the connection parts
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/31515 Connection of piston with piston rod
• CPC Class Codes: A61M 5/5066 Means for preventing re-use by disconnection of piston and piston-rod

Abstract

A nozzle assembly adapted for an injector, includes a frangible plunger. The plunger has a first driving member and a second driving member connected to the first driving member and spaced apart therefrom by a predetermined gap using a frangible bridge. When a predetermined force is applied to the second driving member, it breaks the frangible bridge and moves the second driving member across the gap. This causes the second driving member to ram into the first driving member driving fluid out of the nozzle. Thereafter, as the second driving member is separated from the first driving member, the first driving member remains stuck in the chamber preventing reuse of the nozzle assembly.

Claims

1. A nozzle assembly adapted for use with an injector device comprising:

a chamber for holding a fluid and having first and second ends with an orifice at the first end for passage of the fluid and being open at the second end; and

a plunger slidingly received in said chamber for expelling fluid out of or drawing fluid into the chamber by moving the plunger relative to the chamber, the plunger comprising first and second driving members which include respective end and base portions retained in spaced relation by a frangible connection therebetween, with the second driving member being spaced apart from the first driving member by a gap, such that when a force sufficient to break the frangible connection is applied to the second driving member in a direction toward the first driving member, the frangible connection is broken and the second driving member moves across said gap toward the first driving member, the frangible connection is broken and the second driving member moves across said gap toward the first driving member for urging the first driving member towards the chamber orifice to expel fluid therefrom, and when the second driving member is thereafter moved away from the first driving member, the first driving member remains in the chamber to prevent reuse of the nozzle assembly.

2. The nozzle assembly according to claim 1, wherein the frangible connection has a smaller cross-sectional area than either of the first and second driving members.

3. The nozzle assembly according to claim 1, wherein the first driving member has a seal in contact with an inner wall of the chamber to prevent fluid from exiting the chamber around the first driving member and through the open end.

4. The nozzle assembly according to claim 1, wherein the chamber includes a connector adapted for connecting the nozzle to the injector.

5. The nozzle assembly according to claim 1, wherein the frangible connection is disposed perpendicular to the longitudinal axis of the end portions of the first and second driving members.

6. The nozzle assembly of claim 1 wherein the second driving member includes an end post which can be grasped to move the second driving member in a direction away from the chamber orifice to either draw fluid into the chamber or to remove the second driving member from the chamber.

7. The nozzle assembly of claim 1 wherein the chamber includes a tapered portion adjacent the orifice and the first driving member includes a tapered cone which conforms to the tapered portion of the chamber.

8. The nozzle assembly of claim 1 wherein the first and second driving members are cylindrical and have D-shaped end portions which face each other and are joined by the frangible connection.

9. The nozzle assembly of claim 8 wherein the frangible connection is a rectangular bridge connecting straight sides of the D-shaped portions of the first and second driving members.

10. A nozzle assembly adapted for use with an injector device comprising:

a chamber for holding a fluid and having first and second ends with an orifice at the first end for passage of the fluid and being open at the second end; and

a plunger slidingly received in said chamber for expelling fluid out of or drawing fluid into the chamber by moving the plunger relative to the chamber, the plunger comprising first and second driving members and a frangible connection therebetween, with the second driving member being spaced apart from the first driving member by a gap, such that when a force sufficient to break the frangible connection is applied to the second driving member in a direction toward the first driving member, the frangible connection is broken and the second driving member moves across said gap toward the first driving member, the frangible connection is broken and the second driving member moves across said gap toward the first driving member for urging the first driving member towards the chamber orifice to expel fluid therefrom, and when the second driving member is thereafter moved away from the first driving member, the first driving member remains in the chamber to prevent reuse of the nozzle assembly,

wherein the chamber includes external ridges or threads for connection to an injection device.

11. A nozzle assembly adapted for use with an injector device comprising:

a chamber for holding a fluid and having first and second ends with an orifice at the first end for passage of the fluid and being open at the second end; and

a plunger slidingly received in said chamber for expelling fluid out of or drawing fluid into the chamber by moving the plunger relative to the chamber, the plunger comprising first and second driving members which include respective end and base portions retained in spaced relation by a frangible connection therebetween, with the second driving member being spaced apart from the first driving member by a gap, such that when a force sufficient to break the frangible connection is applied to the plunger, the frangible connection is broken and the second driving member moves across said gap toward the first driving member with the end portion of the second driving member contacting the base portion of the first driving member as the end portion of the first driving member is contacted by the base portion of the second driving member for urging the first driving member towards the chamber orifice to expel fluid therefrom.

12. The nozzle assembly of claim 11, wherein the plunger is substantially cylindrical, and each of the end portions is configured and dimensioned to occupy less than half the cross-sectional area of the plunger, wherein the first and second end portions are positioned in subjacent relation after the second member moves across the gap.

13. The nozzle assembly according to claim 11, wherein the frangible connection has a smaller cross-sectional area than either of the first and second driving members.

14. The nozzle assembly according to claim 11, wherein the first driving member has a seal in contact with an inner wall of the chamber to prevent fluid from exiting the chamber around the first driving member and through the open end.

15. The nozzle assembly according to claim 11, wherein the chamber includes a connector adapted for connecting the nozzle to the injector.

16. The nozzle assembly according to claim 11, wherein the frangible connection is disposed perpendicular to the longitudinal axis of the end portions of the first and second driving members.

17. The nozzle assembly according to claim 11 wherein the second driving member includes an end post which can be grasped to move the second driving member in a direction away from the chamber orifice to either draw fluid into the chamber or to remove the second driving member from the chamber.

20. The nozzle assembly according to claim 11 wherein the nozzle is color coded with a specific color corresponding to a predetermined width of said gap.

18. A nozzle assembly adapted for use with an injector device comprising:

a chamber for holding a fluid and having first and second ends with an orifice at the first end for passage of the fluid and being open at the second end; and

a plunger slidingly received in said chamber for expelling fluid out of or drawing fluid into the chamber by moving the plunger relative to the chamber, the plunger comprising first and second driving members and a frangible connection therebetween, with the second driving member being spaced apart from the first driving member by a gap, such that when a force sufficient to break the frangible connection is applied to the plunger, the frangible connection is broken and the second driving member moves across said gap toward the first driving member for urging the first driving member towards the chamber orifice to expel fluid therefrom,

wherein the first and second driving members are cylindrical and have substantially D-shaped end portions which face each other and are joined by the frangible connection.

19. The nozzle assembly according to claim 18 wherein the frangible connection is a rectangular bridge connecting straight sides of the D-shaped portions of the first and second driving members.